Clinical trials: Locoregional Anaesthesia
Intracranial Aneurysm
General Anesthesia vs Local Anesthesia for Endovascular Treatment in Patients With Unruptured Intracranial Aneurysm Using Flow Diverter
The prevalence of unruptured intracranial aneurysm (UIA) in the population is about 2%-7%, and once it ruptures and bleeds, the rate of disability and death is extremely high, with 10%-15% of patients dying suddenly before they…
- Trial name
- GALA-FD (NCT06416657)
- Testing
- Different anesthesia methods, namely local anesthesia and general anesthesia
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Ming Lv
Assessing the Effect of Acupoint Massage on Pain and Anxiety in Patients Undergoing Surgery Under Local Anesthesia
The Effectiveness of Acupressure on the Physiological and Psychological Improvement of Patients Undergoing Local Anesthesia
Background: Local anaesthesia surgeries are outpatient procedures that allow patients to go home the same day. However, these surgeries often cause pain and anxiety for patients.
- Trial name
- LA (NCT06681519)
- Testing
- Experimental Group 1 - Acupoint Pressure Experimental Group 2 - Pressure Ball Control Group - Conventional Treatment
- Where
- 2 sites in Taiwan
- Volunteers
- 120 people
- Sponsor
- Yu-Jui Feng
Haemophilia A, Haemophilia B
Safety of Intraosseous Anaesthesia in Children With Haemophilia
Effective local anaesthesia is essential for safe and comfortable dental treatment in children with haemophilia. However, conventional nerve block techniques, particularly inferior alveolar nerve block, carry an increased risk of…
- Conditions
- Haemophilia A, Haemophilia B, Dental Caries
- Trial name
- NCT07916467
- Testing
- Intraosseous Anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ankara Yildirim Beyazıt University
Clavicle Fracture, Clavicle Injury
US Guided WALLANT vs CPB Block for Clavicle Surgery
The clavicle is frequently fractured bone. regional anesthesia (RA) for clavicle surgery is always challenging due t complex innervation from the two plexuses (cervical and brachial).
- Trial name
- WALANT-CPB (NCT06106399)
- Testing
- WALLANT
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Al-Azhar University
Knee Arthropathy, Postoperative Pain
Optimization of a Fast-track Concept for Knee Joint Replacement
In an estimated 150,000 patients, a knee joint replacement is performed in Germany every year. The perioperative care of the patients aims at an optimal surgical technique, which leads to a high functionality in the joint, and…
- Conditions
- Knee Arthropathy, Postoperative Pain, Postoperative Complications
- Trial name
- KneeOptOut2 (NCT03920930)
- Testing
- Late local infiltration analgesia, Early local infiltration analgesia
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Charite University, Berlin, Germany
Molar-Incisor Hypomineralization, Molar-Incisor Hypomineralization (MIH)
Comparison of Computer-Assisted and Conventional Local Anesthesia in Children With Molar-Incisor Hypomineralization
The main questions this study aims to answer are: Does computer-controlled local anesthesia cause less pain and anxiety than conventional local anesthesia in children with molar-incisor hypomineralization (MIH)? Is there a…
- Conditions
- Molar-Incisor Hypomineralization, Molar-Incisor Hypomineralization (MIH), Computer-Controlled Local Anesthesia
- Trial name
- NCT07733011
- Testing
- Computer-Controlled Local Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Marmara University
Anesthesia, Conduction, Arthroplasty, Replacement, Knee
Concentration Effect of Local Anesthetics on Femoral Nerve Block Efficiency
US-guided femoral nerve block is used effectively in post-operative pain management in the surgical treatment of the lower extremity.
- Conditions
- Anesthesia, Conduction, Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- NCT03623230
- Testing
- Ultrasound Guided Femoral Nerve Block, Dressing, Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Bozyaka Training and Research Hospital
Thoracic Paravertebral Block
Thoracic Paravertebral Catheters
Thoracic operations are known to be painful and requiring an adequate postoperative pain therapy. A well documented technique to achieve postoperative analgesia is the use of paravertebral catheters.
- Trial name
- NCT01009398
- Testing
- Fluoroscopic examination
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Complication of Surgical Procedure, Acute Respiratory Failure, Adult
Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric…
- Conditions
- Complication of Surgical Procedure, Acute Respiratory Failure, Adult, Postoperative Respiratory Complications, Pulmonary Failure
- Trial name
- PERISCOPE (NCT01346709)
- Where
- 63 sites in Albania, Belgium and 19 more
- Volunteers
- 5,450 people
- Sponsor
- European Society of Anaesthesiology
Knee Osteoarthritis (OA), Postoperative Pain
Effect of Adding a Biceps Femoris Short Head Block to Adductor Canal Block for Analgesia After Total Knee Arthroplasty
Total knee arthroplasty (TKA) is frequently associated with moderate to severe postoperative pain, which may delay mobilization, increase opioid consumption, and impair functional recovery.
- Trial name
- BiFeS-TKA (NCT07803887)
- Testing
- Ultrasound-Guided Adductor Canal Block, Ultrasound-Guided Biceps Femoris Short Head Block
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Antalya Training and Research Hospital
Inferior Alveolar Nerve Injuries
Risk of Nerve Damage After Administration of Local Anesthesia
This research aims to evaluate of the risk of nerve damage following the administration of articaine 4% and lidocaine 2% for Inferior Alveolar nerve Block (IANB).
- Trial name
- NCT06564987
- Testing
- 4% Articaine with 1:200,000 epinephrine, 2% lidocaine with 1:100,000 epinephrine
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Oxidative Stress
Comparison of Oxidants and Antioxidants in Breastmilk Under Different Anesthesia Protocols
The goal of this observational study is to determine in women undergoing cesarean section if total oxidant status and total antioxidant status in breastmilk taken at the 6th hour postoperatively changes between general and…
- Trial name
- NCT06811714
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Duzce University
Pacemaker, Artificial
A Pilot Study on Pacemaker Interference From Peripheral Nerve Stimulator for Regional Anesthesia
In this prospective pilot study, we proposed to evaluate the effects of left interscalene stimulation on cardiac pacemaker function.
- Trial name
- NCT00586248
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nerve Block, Regional Anesthesia
Classic Versus Interfascial Axillary Block in Hand, Wrist, and Forearm Surgery
Hand, wrist, and forearm surgeries are commonly performed procedures with significant postoperative pain potential. Regional anesthesia of the brachial plexus via the axillary approach is one of the gold-standard techniques for…
- Conditions
- Nerve Block, Regional Anesthesia, Upper Extremity Surgery
- Trial name
- NCT07823738
- Testing
- Classic Axillary Block, Interfascial Axillary Block
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Regional Anesthesia Morbidity
Effect of Modified 45-degree Head-up Tilt Position in Cesarean Operation to the Success of Spinal Anesthesia
The success of the application of spinal block in 3 different application as the sitting position, side decubitus position and 45 degrees head upside side decubitus position will be evaluated.
- Trial name
- cesarean (NCT03740399)
- Testing
- spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Trakya University
Pain, Procedural Pain
E-MOHS Trial of TENS and Vibration During Local Anesthesia
The E-MOHS Trial is a randomized controlled trial evaluating whether active vibration plus transcutaneous electrical nerve stimulation reduces pain during local anesthetic infiltration in adults undergoing Mohs micrographic…
- Conditions
- Pain, Procedural Pain, Local Anesthesia, Mohs Surgery
- Trial name
- E-MOHS (NCT07852455)
- Testing
- Active Vibration:TENS
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Minnesota
Diabetes Mellitus Type 2
Intraseptal and Periodontal Ligament Anaesthesia for Tooth Extraction in Patients With Type 2 Diabetes
The goal of this clinical trial is to compare two local anesthesia techniques, intraseptal anesthesia (ISA) and periodontal ligament anesthesia (PLA), in patients with controlled type 2 diabetes mellitus undergoing tooth…
- Trial name
- NCT07647406
- Testing
- Intraseptal anaesthesia (ISA), Periodontal ligament anaesthesia (PLA)
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- University of Business Academy in Novi Sad, Serbia
Achilles Entesopathy
Resistance Training and Injection Treatment for Achilles Enthesopathy
Achilles enthesopathy is a common and often long-lasting injury among exercising individuals. Very little is known regarding the effect of different treatment strategies.
- Trial name
- NCT04232358
- Testing
- Corticosteroid injection, Local anesthesia injections
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Bispebjerg Hospital
Anesthesia, Local, Shoulder Surgery
The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine
This study will test the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia, and that the magnitude of the effect differs among the two local anaesthetics..
- Trial name
- NCT00801138
- Testing
- saline, Dexamethasone, ropivacaine
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- The Cleveland Clinic
Anesthesia, Anxiety
Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia
The present study will evaluate the effectiveness of Buzzy Bee in reducing pain and physiological responses during maxillary buccal infiltration in children aged 5-7 years compared with a conventional injection protocol.
- Conditions
- Anesthesia, Anxiety, Pain, Children
- Trial name
- NCT07886333
- Testing
- Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.