Clinical trials: Locoregional Anaesthesia
Urinary Catheters, Retention, Urinary
Evaluation of a Novel Medical Device to Facilitate Gel Instillation During Change of Long-term Urinary Catheters
A randomized, open label, controlled, parallel group study to investigate difference between regional standard procedure and a novel modified procedure (using an additional novel device to facilitate gel installation) for…
- Conditions
- Urinary Catheters, Retention, Urinary, Incontinence, Urinary, Anesthesia, Local
- Trial name
- NCT03289117
- Testing
- Novel gel installation device procedure, Standard procedure
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Region Skane
Herniated Disk Lumbar
Lumbar Spine Surgery: Regional vs. General Anaesthesia
Background: Lumbar spine surgery can be performed using different anaesthetic techniques such as general endotracheal anaesthesia (GA) or spinal-based regional anaesthesia (RA), that have different side effect profiles (e.g.
- Trial name
- NCT03300089
- Testing
- General anaesthesia, Regional anaesthesia
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- St. Anna Clinic Luzern
Anesthesia, Local
Study of Two-step Anesthesia in Posterior Vitrectomy
A prospective, randomised, single-masked comparison of local anaesthetic approaches including topical anesthesia combined sub-conjunctival anesthesia(two-step anesthesia) for minimally invasive vitrectomy（TAMIV）vs peribulbar…
- Trial name
- NCT03577574
- Testing
- retrobulbar anesthesia, peribulbar anesthesia, two step anesthesia
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Chest Pain, Pain, Procedural
Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure.
Our study consists of a combination of regional blockade ('local' anesthesia) of the anterior and lateral chest wall in the form of a thin needle prick and the supply of local anesthetic drugs to the area of the relevant chest…
- Conditions
- Chest Pain, Pain, Procedural, Pain, Postoperative, Analgesia
- Trial name
- NCT06520150
- Testing
- Regional anaesthetic combined fascial plane block, Ropivacaine 0.125% Injectable Solution +Lignocaine 0,25% Injectable Solution
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Adult Patient Undergoing Elective Surgery With Spinal Anesthesia
Comparison Between Vapocoolant Spray and Eutectic Mixture of Local Anesthetics in Reducing Pain From Spinal Injection
This study aimed to evaluate the effect of vapocoolant spray and EMLA in reducing pain from spinal injection
- Trial name
- NCT03134391
- Testing
- Vapocoolant spray, EMLA
- Where
- Indonesia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Adrenal Cortex Hormones, Arthroplasty, Replacement, Knee
Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty
This study aims to compare the efficacy of different doses of glucocorticoids in local infiltration analgesia (LIA) during total knee arthroplasty (TKA) through a prospective single-center randomized controlled trial, and to…
- Conditions
- Adrenal Cortex Hormones, Arthroplasty, Replacement, Knee, Anesthesia, Local
- Trial name
- NCT07337772
- Testing
- LIA with different doses of Diprospan
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
PLEURA DISEASE
Ultrasound Guided Erectror Spinae Block Versus Intracavitary During Medical Thoracoscopy
The primary aim: is to compare the effect of US guided ESP block at two levels versus intracavitary blockade in medical thoracoscopy on total peri-procedural (intraoperative and post-operative 12 hours) nalbuphine consumption…
- Trial name
- ESPB (NCT07572019)
- Testing
- ultrasound-guided erector spinae plane block in medical pleuroscopy, Intracavitary anaesthesia ICA
- Volunteers
- 100 people
- Sponsor
- Kafrelsheikh University
Long-Eye Surgeries
Remifentanil and Remimazolam to Limit Patient Movement
Local anesthetics (LA) may be administered by injection (retrobulbar, peribulbar, subconjunctival, lid, or facial block) or by instillation (topical anesthesia), Considerable drawbacks of local anesthesia in these patients…
- Trial name
- NCT06583811
- Testing
- Remifentanil
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Egymedicalpedia
Pain, Postoperative
Transversus Abdominis Plane Block Versus Quadratus Lumborum Block in The Pediatric Population Undergoing Orchiopexy
Transversus abdominis plane (TAP) and Quadratus lumborum (QL) blocks are used for the management of acute pain treatment, especially after the lower and upper abdominal surgeries.
- Trial name
- NCT03969316
- Testing
- Transversus abdominis plane block, Quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Istanbul University - Cerrahpasa
Hand Surgery, Quality of Recovery
Local Anesthesia With Minimal Sedation and Brachial Plexus Block in Hand Surgery
A major innovation in hand surgery in the last decade is the popularization of Wide Awake Hand Surgery (WAHS). This technique consists of numbing the surgical area with local anesthesia with epinephrine and allowing the patient…
- Conditions
- Hand Surgery, Quality of Recovery, Hand Injuries, Hand Fracture
- Trial name
- NCT03632304
- Testing
- Local anesthesia with minimal sedation
- Where
- 2 sites in Canada
- Volunteers
- 105 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Delivery
Compared Efficacy of Patient-controlled Epidural Analgesia With or Without Automatic Boluses
Epidural analgesia is a significant feature of the everyday experience of the delivery room. Its benefits on the maternal experience and in terms of security has been widely demonstrated.
- Trial name
- FREE BOLI (NCT03407209)
- Testing
- consumption of local anesthetic measurement
- Where
- France
- Volunteers
- 462 people
- Sponsor
- University Hospital, Caen
Anesthetics, Local, Nerve Block
Thermal QST for Interscale Block Evaluation
Thermal quantitative sensory testing (QST) is a method to evaluate peripheral nerve blocks in a quantitative way. It assesses the neurosensory effects of local anesthetics, like nerve block intensity, duration, recovery…
- Trial name
- NCT02271867
- Testing
- Interscalene block
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- University Hospital, Antwerp
Regional Anesthesia
Comparison of Caudal Block and Retrolaminar Block for Circumcision
Primary Outcome: Analgesic Efficiency: The primary outcome is the comparison of the analgesic efficacy of the retrolaminar block (RL) versus caudal block (CB) based on postoperative pain scores measured by the FLACC score.
- Trial name
- NCT06584292
- Testing
- caudal block, Retrolaminar block
- Where
- Turkey (Türkiye)
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Anesthesia, Spinal Puncture
Intravenous Fentanyl or Local Anesthetic Infiltration for Pain Reducing During Spinal Needle Insertion
Background and Objectives: Spinal puncture is painful procedure which may cause patient refusal of spinal anesthesia in future surgery.
- Trial name
- NCT01157247
- Testing
- Comparison of intravenous fentanyl and local anesthetic infiltration in pain reducing during spinal needle puncture
- Where
- Croatia
- Volunteers
- 88 people
- Sponsor
- Croatian Society of Regional Anesthesia and Analgesia
Symptomatic Irreversible Pulpitis
Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis
The purpose of this study is to determine whether one type of anesthetic (numbing medicine) will work better at numbing the nerve in a tooth than using a different type of anesthetic.
- Trial name
- NCT05227300
- Testing
- Onset Sodium Bicarbonate Inj., 8.4%, USP Neutralizing Additive Solution, 2% lidocaine with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
Thoracic Paravertebral Block
Thoracic Paravertebral Catheters
Thoracic operations are known to be painful and requiring an adequate postoperative pain therapy. A well documented technique to achieve postoperative analgesia is the use of paravertebral catheters.
- Trial name
- NCT01009398
- Testing
- Fluoroscopic examination
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain
Efficacy of Repeated Locoregional Anesthetics Blocks With Bupivacaine in Patients Suffering of Chronic Dentoalveolar Pain.
The aim of this study is to evaluate the efficacy of anesthetic blocks repeated with bupivacaine in the management of patients with persistent dentoalveolar pain.
- Trial name
- BADDAP (NCT04207411)
- Testing
- Bupivacaine, Lidocaine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Brachial Plexus Block, Anesthetics, Local
Analgesic Duration of Long Acting Local Anesthetics for Low Volume Ultrasound-guided Interscalene Brachial Plexus Block
Severe pain following shoulder surgery is common and remains a major challenge. The interscalene nerve block is well suited for operations on the shoulder or upper arm, for providing surgical anesthesia as well as prolonged…
- Trial name
- NCT02643563
- Testing
- Ropivacaine 0.5%, Ropivacaine 1%, Bupivacaine 0.5% + epinephrine 1:200,000
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Anesthesia, Conduction, Nerve Block
Neurologic Complications in Peripheral Regional Anesthesia - An Evaluation Based on a Standardized Protocol
To evaluate the incidence of neurologic complications as a consequence of peripheral regional anesthesia, all patients receiving peripheral nerve blocks will be evaluated according to a standardized protocol screening pain…
- Conditions
- Anesthesia, Conduction, Nerve Block, Adverse Effects
- Trial name
- NCT00445016
- Testing
- peripheral regional anesthesia
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- BG Unfallklinik Murnau
Pain, Postoperative
Popliteal Plexus Block for Total Knee Arthroplasty
This study aims to assess the analgesic effect of the popliteal plexus block as a supplement to a femoral triangle block in patients undergoing total knee arthroplasty
- Trial name
- NCT03439787
- Testing
- Bupivacaine-EPINEPHrine 0.5%-1:200,000 Injectable Solution, Sodium Chloride 0.9 %
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
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