Clinical trials: Long Term Pain
Dentine Hypersensitivity
The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over an eight week treatment period.
- Trial name
- NCT01592864
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Chronic Low-back Pain
The ECEALT Chronic Low Back Pain Study
The primary objective of this double-blind randomized control trial (RCT) is to evaluate the clinical effectiveness of LLLT as adjunctive therapy to standard exercise treatment in patients with non-specific chronic LBP.
- Trial name
- NCT05040633
- Testing
- BTL 4110 Smart Laser Therapy Equipment (BTL Industries Ltd, United Kingdom (UK)), Standard Exercise Therapy
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Health Rehab and Research Clinic
Hip Osteoarthritis
Hip Osteoarthritis: Effects of Exercise Programs on Pain and Disability
Osteoarthritis is the most common form of arthritis in the United States. It is estimated that 20 million Americans have arthritis, and the annual societal cost is $95 billion.
- Trial name
- NCT00682617
- Testing
- Structured exercise program, Waitlist, delayed intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Low Back Pain
Assessment of LTP-like Pain Amplification in Chronic Low Back Pain Patients
The present study is aimed to assess the LTP-like pain amplification in chronic low back pain patients to explore the central and peripheral effect for pain LTP.
- Trial name
- NCT03362827
- Testing
- Chronic low back pain patients, Subjects without chronic low back pain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Chronic Pain, Pain, Musculoskeletal
Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment
This study will use multiple methods to assess the feasibility of conducting a fully powered multisite clinical trial to test the effectiveness of integrating mindfulness-based interventions into physical therapy for patients…
- Conditions
- Chronic Pain, Pain, Musculoskeletal, Opioid Use, Physical Therapy
- Trial name
- PT-IN-MIND (NCT05875207)
- Testing
- Mindfulness based practice, Control/Standard Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Utah
Lateral Epicondylitis
Immediate and Longterm Effects of Mulligan Mobilization With and Without Myofascial Release on Pain,Grip Strength and Function in Patients With Lateral Epicondylitis
This study will help to determine the immediate and long term effects of Mulligan mobilization with and without myofascial release on pain, grip strength and function in patients with lateral epicondylitis
- Trial name
- NCT05566418
- Testing
- mulligan mobilization, myofascial release
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Development of Computational Models to Predict the Short-, Medium- and Long-term Cartilage Degeneration and Pain for Patients With Early-stage Osteoarthritis or Anterior Cruciate Ligament Injury
Knee osteoarthritis is a complex condition, and selecting effective non-drug treatments like orthoses or exercise is often difficult and imprecise.
- Trial name
- MathKOA (NCT07134244)
- Where
- 2 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Oxidative Stress, Inflammation
Oxidative Stress and Nutritional Supplementation Intervention Study
A major means whereby oxidative stress promotes aging-related disease is by activating inflammatory pathways. Decreasing oxidative stress and inflammation should ameliorate many of the problems associated with aging, including…
- Conditions
- Oxidative Stress, Inflammation, Aging, Dementia
- Trial name
- Oxi-Stress (NCT01234506)
- Testing
- secoisolariciresinol diglucoside
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Vestibular Disease, Musculoskeletal Pain
Musculoskeletal Pain in Long-term Dizziness
This project is aimed at patients with dizziness believed to be due to conditions in the balance organ in the inner ear (vestibular diseases).
- Conditions
- Vestibular Disease, Musculoskeletal Pain, Rehabilitation
- Trial name
- MUPID (NCT04241822)
- Testing
- Vestibular exercises combined with body awareness exercises and cognitive therapy, Exergaming
- Where
- Norway
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Western Norway University of Applied Sciences
Pain, Pain, Chronic
Long Term Use of a High Energy Pulsed Heating Device in the Management of Chronic Pain
The purpose of this study is to evaluate the Soovu Labs pain Relief System in a group of users that represent people most likely to purchase and use the units. This study is called an In Home Users Trial (IHUT).
- Conditions
- Pain, Pain, Chronic, Pain, Back
- Trial name
- NCT04407884
- Testing
- Soovu Labs Inc. Pain Relief System
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Soovu Labs Inc.
Dentin Sensitivity
A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.
This will be a single center, eight week, randomized, double blind, three treatment arm, parallel design, stratified (by mean baseline Schiff Sensitivity Score of the two selected test teeth) study in healthy participants.
- Trial name
- NCT02651467
- Testing
- Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0), Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pain, Postoperative, Neural Therapy of Huneke
Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation
The aim of this study was to explore the effect of neural therapy on postoperative pain and discomfort such as abdominal swelling; and gynecologic symptoms such as dysmenorrhea, dyspareunia, amount of menstrual bleeding and…
- Conditions
- Pain, Postoperative, Neural Therapy of Huneke, Dysmenorrhea, Dyspareunia
- Trial name
- NCT03761862
- Testing
- Neural Therapy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Chronic Pain, Pain
Classifying and Predicting Long-term Pain and Function in Older Adults
This project will use novel methods to detect clinically meaningful subgroups of older adults based on long-term trajectories of bothersome pain and function.
- Trial name
- NCT04864223
- Where
- United States
- Volunteers
- 6,783 people, healthy volunteers welcome
- Sponsor
- University of Washington
Stress Urinary Incontinence, Postsurgical Pain
The Follow-up After Shorter Tapes Study. Effectiveness and Safety of Shorter Trans-obturator Tapes.
Urinary incontinence after pregnancy and labor affects 1 in 3 women and has a negative impact on quality of life (QOL), limiting women's physical activity and impairing sexual function.
- Conditions
- Stress Urinary Incontinence, Postsurgical Pain, Follow-Up Studies
- Trial name
- FAST (NCT06731985)
- Where
- Norway
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Training, Quality of Care
Training and Support Programme on Data-driven Quality Development for Swiss Long-Term Care Facilities (NIP-Q-UPGRADE Subaim 2.6)
Since 2019, long-term care facilities (LTCFs) in Switzerland have been required by the Federal Insurance Law (KVG, Art. 59a) to report data for the calculation and public reporting of medical quality indicators (MQIs) in four…
- Conditions
- Training, Quality of Care, Quality Indicators, Health Care, Long Term Care
- Trial name
- NCT07068009
- Testing
- Training and Support Programme on Data-driven Quality Development
- Where
- 3 sites in Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Institut et Haute Ecole de la Santé la Source
Training, Exercise
Hypoalgesic Effects of Exercise and Training of Different Modalities
Further research is needed to explore the analgesic effects of post-acute and chronic exercise and if effects are partially dependent on lower H-reflex/V-wave inhibition by group III and IV muscle afferents desensitization.
- Conditions
- Training, Exercise, Fatigue, Occlusion
- Trial name
- NCT07105410
- Testing
- Aim #1: The effect of post-exercise circulatory occlusion on H-reflex and V-wave, Aim #2: The hypoalgesic effects of acute exercise of different modalities, Aim #3: The hypoalgesic effects of chronic training of different modalities
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Peripheral Neuropathy
Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain
The purpose of this study to evaluated Long term outcome after serial Lidocaine infusion when compared with placebo in peripheral neuropathic pain patients in acute stage (less than 6 months) at 3 months after first time of…
- Trial name
- NCT02217267
- Testing
- Lidocaine
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pain, Traumatic Memory
Traumatic Long-term Memory of Pain in Humans
Few studies have focused on understanding the mechanisms underlying pain memory in humans. Thus, this project aims to investigate the link between pain memorisation and memorisation of the associated context by addressing the…
- Trial name
- TRAUMADOL (NCT04189965)
- Testing
- Validation of virtual environment and auditive stimulation with virtual reality glasses (Pilot phase), Electrical cutaneous stimulation and auditive stimulation (Principal Experimental phase), Electrical cutaneous stimulation and auditive stimulation (Secondary Experimental phase)
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative
Persistent Postoperative Pain Incidence With Gabapentin Used
The study's objective will be to evaluate the gabapentine efficiency in orally and long term used after painfully surgeries.
- Trial name
- PPP (NCT02693821)
- Testing
- Gabapentin
- Where
- Argentina
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Osteoarthritis
Synvisc-One for Younger, Active Patients With Osteoarthritis
This study aims to study use of viscosupplementation as a treatment of pain for young individuals who are active. Typically viscosupplementation is considered an intervention for knee osteoarthritis often for older patients who…
- Trial name
- SYNVISC-ONE (NCT01625013)
- Testing
- Synvisc-One (G-F 20)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Anthony Luke