Clinical trials: Long Term Pain
Conventional Radiofrequency Thermocoagulation Application to the Articular Branches of the Femoral and Obturator Nerve, Chronic Hip Pain
Long-Term Follow-up of Radiofrequency to Articular Branches of the Femoral and Obturator Nerve in Chronic Hip Pain
It has been observed that the deterioration in the physical performance of the hip, the medical need before the specialist consultation and the deterioration in the health status can progress treatment[3].
- Trial name
- NCT06751472
- Testing
- VPS (Verbal Pain Score), WOMAC (Western Ontario and McMaster Universities Arthritis Index) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Aydin Adnan Menderes University
Pain
Study of Embeda (Kadian NT, ALO-01) in Subjects With Chronic Moderate to Severe Nonmalignant Pain
Open-Label, Safety Study to evaluate the long-term safety of Kadian NT (ALO-01) administered for up to 12 months.
- Trial name
- NCT00415597
- Testing
- ALO-01 (Morphine Sulfate Plus Naltrexone Hydrochloride ER)
- Where
- 58 sites in United States
- Volunteers
- 467 people
- Sponsor
- Pfizer
Diabetic Neuropathy, Painful
A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to assess the safety and efficacy of the long-term use of pregabalin at doses up to 600 mg/day in patients with painful diabetic peripheral neuropathy who have completed 13 weeks of dosing in Study…
- Trial name
- NCT00553280
- Testing
- pregabalin
- Where
- 27 sites in Japan
- Volunteers
- 123 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Diabetes, Chronic Pain
iCBT for Long-term Conditions in IAPT
SilverCloud provides internet-delivered interventions for depression and anxiety in NHS Mental Health Services. The interventions have proved successful in the management of depression and anxiety for clients presenting to mental…
- Conditions
- Diabetes, Chronic Pain, COPD, CHD - Coronary Heart Disease
- Trial name
- NCT03068286
- Testing
- Space in Diabetes, Space in COPD, Space in Chronic Pain
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Derek Richards
Pain, Chronic Pain
Efficacy and Tolerability of Lidocaine Plaster for Treatment of Long-term Local Nerve Pain
The purpose of this trial is to investigate the efficacy and safety of lidocaine 5% medicated plaster in localized chronic post-operative neuropathic pain in comparison to placebo plaster.
- Conditions
- Pain, Chronic Pain, Neuropathic Pain, Postoperative Pain
- Trial name
- NCT01752322
- Testing
- Lidocaine 5% medicated plaster
- Where
- 42 sites in Austria, Belgium and 6 more
- Volunteers
- 444 people
- Sponsor
- Grünenthal GmbH
Low Back Pain
Cost of Long Term Disability in Patients With Chronic Non-Specific Low Back Pain
The purpose of the study was to determine the cost-effectiveness of a function-centred treatment (FCT) compared with a pain-centred treatment (PCT) in patients with chronic low back pain (LBP) in an in-patient setting.
- Trial name
- NCT00652236
- Testing
- Physiotherapy
- Where
- Switzerland
- Volunteers
- 174 people
- Sponsor
- Klinik Valens
Traumatic Brain Injury (TBI)
Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation
Persistent headache is one of the most common debilitating symptoms in military personnel suffering from mild traumatic brain injury (MTBI).
- Trial name
- NCT03314584
- Testing
- Transcranial Magnetic Stimulation, Magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- VA Office of Research and Development
Low Back Pain
Specific or Non-Specific Manipulation for Patients With Back Pain
We aim to evaluate the long-term effects of 10 sessions of spinal manipulative therapy applied in a vertebral region-specific or region nonspecific level immediately after treatment and 3 and 6 months after randomization.
- Trial name
- NCT02883634
- Testing
- Specific manipulation, Non-specific manipulation
- Where
- Brazil
- Volunteers
- 148 people
- Sponsor
- Universidade Cidade de Sao Paulo
Chronic Pain
Lichtenstein Patch or Prolene Hernia System (PHS) for Inguinal Hernia Repair
This randomised prospective study was designed to compare the convalescence and the long-term sequelae in inguinal hernia repair with either a bilayer mesh as devised by Gilbert (Prolene Hernia System®) or an onlay mesh applied…
- Trial name
- NCT01070693
- Testing
- Open mesh inguinal hernia repair, Prolene Hernia System, Lichtenstein technique
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Helsinki University Central Hospital
Chronic Low-back Pain
The ECEALT Chronic Low Back Pain Study
The primary objective of this double-blind randomized control trial (RCT) is to evaluate the clinical effectiveness of LLLT as adjunctive therapy to standard exercise treatment in patients with non-specific chronic LBP.
- Trial name
- NCT05040633
- Testing
- BTL 4110 Smart Laser Therapy Equipment (BTL Industries Ltd, United Kingdom (UK)), Standard Exercise Therapy
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Health Rehab and Research Clinic
Anesthesia, Local, Pain, Postoperative
Pain Management After TKA: Comparison of Short- and Long-term Nerve Blocks
The purpose of this study is to determine if there is any significant difference between using a short-term ON-Q nerve block (which is applied prior to surgery and maintained in place until the medication in the initial balls…
- Trial name
- NCT03245359
- Testing
- Short-term ON-Q, Long-term ON-Q
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- AdventHealth
Partial Pneumonectomy Under Lateral or Posterolateral Thoracotomy.
Effects of Perioperative Systemic Ketamine on Development of Long-term Neuropathic Pain After Thoracotomy
Lung surgery under thoracotomy is known to induce long-term pain which can be considered as neuropathic in many patients concerned [1,2]. The suspected origin of neuropathy is a direct traumatism of intercostal nerve(s) [3].
- Trial name
- NCT00313378
- Testing
- Hypothetica
- Where
- France
- Volunteers
- 78 people
- Sponsor
- University Hospital, Clermont-Ferrand
Failed Back Surgery Syndrome
Objective Data on Daily Activity in Patients Treated with SCS: the Intellis Study
In spinal cord stimulation (SCS), most outcome data are based on patient questionnaires. The lack of tools for objective evaluation of the effects of SCS on chronic pain has posed a barrier for providing solid proof of the…
- Trial name
- NCT04710355
- Testing
- Spinal cord stimulation
- Where
- 7 sites in Belgium, Denmark and 2 more
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Patellofemoral Pain Syndrome
Efficacy Analysis in Long Term of Radiofrecuency Combined vs. T.E. in the Treatment of Patellofemoral Pain Syndrome.
The present study aims to promote research in the field of Physiotherapy, focusing on a health problem of maximum relevance, such as patellofemoral pain syndrome.
- Trial name
- NCT04462718
- Testing
- Radiofrecuency, Therapeutic Exercise
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- University of Seville
Fibromyalgia, Transcranial Direct Current Stimulation
Long Term Home Based tDCS in Fibromyalgia
Fibromyalgia(FM) is a widespread musculoskeletal pain syndrome characterized by fatigue, sleep disorders, cognitive impairment, depressive symptoms and neuro-vegetative symptoms.
- Trial name
- NCT03843203
- Testing
- Transcranial Direct Current Stimulation - tDCS
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Myocardial Infarction, Death
Association of Endothelial Function and Clinical Outcomes in Subjects Admitted to Chest Pain Unit
It is recognized that endothelial dysfunction is a major factor contributing to the atherogenic process. Abnormal function of the endothelium is detectable prior to obvious intimal lesions in patients with risk factors for…
- Conditions
- Myocardial Infarction, Death, Cerebrovascular Accident, Congestive Heart Failure
- Trial name
- NCT01618123
- Where
- 2 sites in United States, Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Sacral Tarlov Cysts, Symptomatic Sacral Cysts
Long-Term Outcomes of Different Surgical Techniques for Sacral Tarlov Cysts: A Prospective Cohort Study
Brief Summary The goal of this observational study is to evaluate the long-term outcomes of different surgical techniques for sacral Tarlov cysts in adult patients aged 18-75 years diagnosed with symptomatic sacral Tarlov cysts.
- Conditions
- Sacral Tarlov Cysts, Symptomatic Sacral Cysts, Chronic Pain Related to Sacral Cysts, Neurological Dysfunction Associated With Tarlov Cysts
- Trial name
- NCT06756984
- Testing
- Partial Cyst Wall Resection with Nerve Root Sleeve Plasty, Partial Cyst Wall Resection with Nerve Root Sleeve Reinforcement and Reconstruction:, Autologous Fat/Muscle with Fibrin Glue Microscopic Cyst Filling
- Volunteers
- 150 people
- Sponsor
- Beijing Jishuitan Hospital
Chronic Stable Angina Pectoris
Outcome Research to Confirm the Anti-anginal Effect of T89 in Patients With Stable Angina
This is a multi-center, double-blind, randomized, placebo-controlled, parallel-group phase 3 clinical study to confirm the safety and efficacy of T89 in patients with stable angina pectoris, with an extended open-label period to…
- Trial name
- NCT03789552
- Testing
- T89 capsule
- Where
- United States
- Volunteers
- 765 people
- Sponsor
- Tasly Pharmaceuticals, Inc.
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization
Hip Osteoarthritis
Hip Osteoarthritis: Effects of Exercise Programs on Pain and Disability
Osteoarthritis is the most common form of arthritis in the United States. It is estimated that 20 million Americans have arthritis, and the annual societal cost is $95 billion.
- Trial name
- NCT00682617
- Testing
- Structured exercise program, Waitlist, delayed intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University