Clinical trials: Long-term Care
Prurigo Nodularis
A Non-interventional Study to Describe the Dupilumab Long-term Treatment, Safety and Patient Reported Outcomes in Chronic Nodular Prurigo (Prurigo Nodularis) in Clinical Routine
Prurigo nodularis (PN) is a skin disease characterized by the presence of single to multiple symmetrically distributed, intensively itching nodules.
- Trial name
- CLEAR PN (NCT06087627)
- Testing
- Dupilumab SAR231893 (REGN668)
- Where
- 11 sites in Germany
- Volunteers
- 110 people
- Sponsor
- Sanofi
Thalassemia Major
Long Term Outcomes in β Thalassemia Major
Beta thalassemia (β-thalassemia) is the most common genetic disease worldwide. Individuals with thalassemia are born with a defect in hemoglobin.
- Trial name
- NCT02307786
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Critical Illness
Being Awake, Upright and Moving as the Basis for Early ICU Physiotherapy
Patients who have been admitted to Intensive Care Units (ICU) and are intubated and mechanically ventilated for longer than 48 hours have impaired physical, psychological and social health and well-being six to twelve months…
- Trial name
- NCT02301273
- Testing
- Usual Physiotherapy, Enhanced Physiotherapy
- Where
- Iceland
- Volunteers
- 60 people
- Sponsor
- Landspitali University Hospital
Atopic Dermatitis
Real-world Effectiveness Study of Long-term Treatment With Dupilumab in Participants ≥6 Years With Atopic Dermatitis
This is a Prospective, non-interventional (NIS) observational study in patients (≥6 years) with atopic dermatitis (AD) receiving dupilumab for the prospective evaluation of signs and symptoms, quality of life and disease control.
- Trial name
- PROTYPE2 (NCT06039241)
- Where
- 55 sites in Germany
- Volunteers
- 572 people
- Sponsor
- Sanofi
Infections
Echinacea Safety Study
Extracts produced from Echinacea purpurea are traditionally used for the prevention and the acute treatment of influenzal infections like the common cold.
- Trial name
- NCT01021995
- Testing
- echinacea
- Where
- United Kingdom
- Volunteers
- 757 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Chronic Non-Cancer Pain, Opioid Use Disorder
Long-Term Opioid Therapy in Chronic Non-Cancer Pain: Risks and Benefits
The study investigates long-term opioid treatment in patients with chronic non-cancer pain (CNCP). The study aims to prospectively identify predictive factors for work ability and for developing opioid use disorder (according to…
- Trial name
- NCT06063902
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Uppsala University
Caregiver, Disabled Veterans
Helping Invested Families Improve Veterans Experiences Study
The purpose of this study is to evaluate a caregiver skill training program (HI-FIVES), offered as a part of a randomized control trial to caregivers of Veterans referred to home and community-based long-term care.
- Conditions
- Caregiver, Disabled Veterans, Referred to Long-term Care, Residing at Home
- Trial name
- HI-FIVES (NCT01777490)
- Testing
- Helping Invested Families Improve Veterans Experiences - Control, Helping Invested Families Improve Veterans Experiences - HI FIVES
- Where
- United States
- Volunteers
- 484 people
- Sponsor
- VA Office of Research and Development
CHRONIC HEPATITIS B
Treatment on HBeAg Positive or HBeAg Negative in Chronic Hepatitis B
Phyllanthus Urinaria - Adenosma Glutinosum - Eclipta Prostrata - Ascorbic Acid combination plus Tenofovir in treatment of acute and chronic hepatitis B.
- Trial name
- HBV (NCT01198860)
- Testing
- CTH Chronic Hepatitis B
- Where
- 2 sites in United States, Vietnam
- Sponsor
- Nguyen Thi Trieu, MD
Lung Diseases, Interstitial
A Study to Evaluate Long-term Safety of Nintedanib in Children and Adolescents With Interstitial Lung Disease (InPedILD®-ON)
This study is open to children and adolescents with interstitial lung disease (ILD) that causes lung fibrosis. This is a study for people who took part in a previous study called InPedILD (study 1199-0337) and for people who are…
- Trial name
- NCT05285982
- Testing
- Nintedanib (Ofev®)
- Where
- 28 sites in United States, Argentina and 15 more
- Volunteers
- 54 people
- Sponsor
- Boehringer Ingelheim
Chronic Obstructive Pulmonary Disease
Long-term Maintenance Benefits of a Pulmonary Rehabilitation Program Using a Mobile Digital Solution: a Prospective, Randomized, Controlled, Multicenter Study in a Population of COPD Patients
Chronic obstructive pulmonary disease (COPD) is a public health problem: high prevalence; increasing morbidity and mortality; impact on health costs.
- Trial name
- m-Rehab COPD (NCT04550741)
- Testing
- telerehabilitation
- Where
- 2 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Hypertension
The Effect of the Patient Activation Measure on Chronic Care
We will test - in a chronically ill managed long term care population - the effectiveness of an intervention that provides nurse Care Managers with an inventory of evidence-based practices tailored to patients with different…
- Trial name
- NCT00299468
- Testing
- Patient Activation Measure Intervention Package
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- Weill Medical College of Cornell University
Alzheimer Disease, Dementia
Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease
This study seeks to evaluate the utility and efficacy of the Non-Contact Sleep Quality Monitor System when used to monitor the sleep quality of individuals living in long-term care (LTC) with either Alzheimer's Disease (AD) or…
- Conditions
- Alzheimer Disease, Dementia, Sleep Disturbance
- Trial name
- NCT06045988
- Testing
- Non-Contact Sleep Quality Monitor System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Stomach Ulcer, Duodenal Ulcer
Efficacy and Safety of Lansoprazole on Gastric and Duodenal Ulcers in Patients Taking Nonsteroidal Anti-Inflammatory Drugs
The purpose of this study is to determine whether AG-1749 (lansoprazole), once daily (QD), is effective in preventing the recurrence of gastric and duodenal ulcers in patients receiving long term treatment with nonsteroid…
- Trial name
- NCT00787254
- Testing
- Lansoprazole, Gefarnate
- Where
- 68 sites in Japan
- Volunteers
- 366 people
- Sponsor
- Takeda
Neurodevelopmental Disorders
Long-term Consequences of Admission for Pediatric Intensive Care Before One Year of Age
This study is a retrospective cohort study. The PICU children will include all surviving children who were admitted to the PICU of Copenhagen University Hospital between 1st of January 2002 and 31st of December 2016.
- Trial name
- NCT04562935
- Testing
- admission to pediatric intensive care with mechanical ventilation
- Where
- Denmark
- Volunteers
- 330 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Recurrent Low Back Pain, Persistent Low Back Pain
Chiropractic Maintenance Care of Persistent or Recurrent Low Back Pain
As low back pain is often a recurrent and sometime persistent problem, research into prevention is important. Chiropractors have traditionally treated patients with maintenance care, which means that patients are seen on a…
- Conditions
- Recurrent Low Back Pain, Persistent Low Back Pain, Chronic Low Back Pain
- Trial name
- NCT01539863
- Testing
- maintenance care, Treatment as needed
- Where
- Sweden
- Volunteers
- 328 people
- Sponsor
- Karolinska Institutet
Lupus Nephritis
A Study to Evaluate the Safety and Efficacy of Tacrolimus for Lupus Nephritis Under Actual Use Situations
To evaluate the safety and efficacy of tacrolimus for lupus nephritis under actual-use.
- Trial name
- TRUST (NCT01410747)
- Testing
- Tacrolimus
- Where
- 8 sites in Japan
- Volunteers
- 1,484 people
- Sponsor
- Astellas Pharma Inc
Spontaneous Subarachnoid Hemorrhage
Long-term Effects of Time to Treatment in Subarachnoid Haemorrhage
For patients with spontaneous subarachnoid haemorrhage, it remains to be investigated if there is an association between the time from patients call the Emergence Medical Coordination Center to neurosurgical admission and…
- Trial name
- NCT04377347
- Testing
- Time
- Where
- Denmark
- Volunteers
- 537 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Migraine
A Study to Evaluate the Tolerability of Botox and Topiramate or Botox and Placebo and Effect on Cognitive Efficiency
The purpose of this study is to evaluate sustained tolerability, quality of life, and change in cognitive efficiency following treatment with OnabotulinumtoxinA and daily topiramate vs.
- Trial name
- NCT01700387
- Testing
- onabotulinumtoxinA, Topiramate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cady, Roger, M.D.
Diabetes
Patient Provider Partnership: Improving Diabetes Care in the Community
With the advent of managed care, increasing responsibility for the care of patients with diabetes is being placed on primary care physicians.
- Trial name
- NCT00167284
- Testing
- physician and patient education; physician practice redesign
- Volunteers
- 270 people
- Sponsor
- University of Pittsburgh
Preterm Birth, Premature Birth
Exposure to Plasticisers in the Neonatal Intensive Care Unit
Neonatal intensive care relies on indwelling plastic medical devices fundamental in respiratory support, intravenous catheterization, and nutrition.
- Conditions
- Preterm Birth, Premature Birth, Neurodevelopmental Disorders, Pulmonary Disease
- Trial name
- PLASTIC-NICU (NCT05404815)
- Where
- Belgium
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp