Clinical trials: Long-term Outcome
Transposition of Great Vessels
Comprehensive Long-term Follow up of Adults With Arterial Switch Operation
Background: Long-term outcomes in adults with prior arterial switch operation (ASO) have not yet been well defined. The aim of this study is to elucidate incidence and predictors of adverse cardiac outcomes in a prospectively…
- Trial name
- EPOCH-ASO (NCT04335448)
- Testing
- No intervention is planed
- Where
- 11 sites in Austria, France and 3 more
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Peripheral Neuropathy
Long Term Outcome After Serial Lidocaine Infusion in Peripheral Neuropathic Pain
The purpose of this study to evaluated Long term outcome after serial Lidocaine infusion when compared with placebo in peripheral neuropathic pain patients in acute stage (less than 6 months) at 3 months after first time of…
- Trial name
- NCT02217267
- Testing
- Lidocaine
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Adrenal Hyperplasia, Congenital
Determining the Long-Term Effects of Prenatal Dexamethasone Treatment in Children With 21-Hydroxylase Deficiency and Their Mothers
Congenital adrenal hyperplasia (CAH) is a genetic disorder that affects the amount of steroids that the body forms. The most common form of CAH is 21-hydroxylase deficiency (21OHD), which leads to cortisol deficiency and causes…
- Trial name
- NCT00617292
- Where
- 4 sites in United States, Brazil and 1 more
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Office of Rare Diseases (ORD)
Multiple Sclerosis
Motor Training and White Matter in Multiple Sclerosis (MS)
In the current study the researchers will firstly investigate whether a bimanual coordination training protocol (20 min/day, for 8 consecutive weeks) correlates with changes in white matter architecture and improved upper-limb…
- Trial name
- NCT01279655
- Testing
- tDCS, Bimanual Training
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hasselt University
COVID-19
This Study Investigate the Impact of Maternal COVID-19 Infection During Birth on the Childrens' Physical and Mental Development.
This study investigates the impact of the maternal COVID infection during birth on the children's development: physical and mental outcomes.
- Trial name
- Coronababies (NCT05430594)
- Where
- Hungary
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Apneas of Prematurity
The Effect of Stimulating Substances on Brain Activity of Preterm Infants
Introduction: Methylxanthines and doxapram have been widely used for the treatment of apneas of prematurity. Both substances have effects on the central nervous system.
- Trial name
- NCT01344317
- Where
- 2 sites in Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Central Nervous System Infection
Long Term Outcomes of EV71 CNS Infection
Our study involved 142 children with EV71 CNS infections that included 61 (43%) with viral meningitis, 53 (37%) with severe CNS involvement including encephalitis, polio-like syndrome and encephalomyelitis, and 28 (20%) with…
- Trial name
- NCT00172393
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Glaucoma, Glaucoma, Open-Angle
Long Term Outcome of Combined Phacoemulsification and Excisional Goniotomy With the Kahook Dual Blade
Purpose: Characterize changes in intraocular pressure (IOP), IOP-lowering medications, and visual acuity (VA) through 3 years in patients undergoing combined phacoemulsification and excisional goniotomy with the Kahook Dual Blade…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, Cataract, Angle Closure Glaucoma
- Trial name
- NCT04476810
- Testing
- kahook dual blade
- Where
- Saudi Arabia
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Ahmed Al Habash
Preterm Birth, Premature Birth
Exposure to Plasticisers in the Neonatal Intensive Care Unit
Neonatal intensive care relies on indwelling plastic medical devices fundamental in respiratory support, intravenous catheterization, and nutrition.
- Conditions
- Preterm Birth, Premature Birth, Neurodevelopmental Disorders, Pulmonary Disease
- Trial name
- PLASTIC-NICU (NCT05404815)
- Where
- Belgium
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Severe Sepsis With Septic Shock, Severe Sepsis Without Septic Shock
Long-term Cognitive and Cerebral Changes in Sepsis Survivors and Their Predictors
The main goals of this study are to provide a cognitive, neurological, brain morphological, and serological profile of sepsis survivors in order to make long-term prognosis of recovery and estimate the need for rehabilitation…
- Trial name
- BonSEP (NCT02339649)
- Testing
- Blood Sample, Neurocognitive Assessment, Resting State EEG
- Where
- 2 sites in Germany
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Myocardial Infarction
Anxiety, Stress and Pain & Myocardial Infarction
People often experience the acute phase of a myocardial infarction as a stressful and traumatic event that seems lifethreatening.
- Trial name
- NCT04130269
- Testing
- No intervention
- Where
- Austria
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Oral Health, Old Age; Dementia
Evaluation of the Use of a Novel Oral Health Screening Instrument by Caregivers in Nursing Homes
BACKGROUND: Oral health of nursing home residents is often poor. Oral health is related to general health, quality of life and well-being.
- Conditions
- Oral Health, Old Age; Dementia, Long-Term Care, Nursing Homes
- Trial name
- OHS-interRAI (NCT06536322)
- Testing
- OHS-interRAI
- Where
- Belgium
- Volunteers
- 462 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Puberty, Precocious, Adiposity
Long-term Outcome of GnRH Analogues Treatment of Children With Idiopathic Central Precocious Puberty
This study evaluates the influence of early adiposity rebound, genetic polymorphisms and GnRHa treatment on long-term outcome of girls with idiopathic central precocious puberty.
- Trial name
- NCT02790112
- Testing
- GnRHas
- Where
- Belgium
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Growth Failure, Adiposity
Optimal Growth of Preterm Infants With Growth Restriction
In this prospective randomized controlled multi center trial the investigators stratify "Very Low Birthweight " (VLBW)-infants with growth retardation in small for gestational age (SGA) or intrauterine growth restricted (IUGR) …
- Conditions
- Growth Failure, Adiposity, Diabetes, Neurologic Deficits
- Trial name
- OPTIGROW (NCT02999945)
- Testing
- SGA-enhanced nutrients, IUGR-enhanced nutrients, SGA-standard nutrients
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Chronic Periodontitis, Generalized, Moderate
Er:YAG Laser Treatment of Moderate Chronic Periodontitis
The Er:YAG laser possesses specific characteristics allowing to be used in non-surgical periodontal treatment. The aim of the resent study was to evaluate the long-term clinical effectiveness of Er:YAG laser monotherapy in the…
- Trial name
- NCT05217823
- Testing
- Er:YAG laser, hand instruments
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Asphyxia Neonatorum
Biomarkers And Neurological Outcome in Neonates (BANON)
Validation of biomarkers in a human population for their ability to diagnose the severity of neonatal asphyxia. These biomarkers linked to asphyxia have been identified in animal studies and a preliminary human study.
- Trial name
- NCT03357250
- Where
- 11 sites in Germany
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Life Science Inkubator
Inflammatory Bowel Disease
Long-term Functional Outcome of Children With Inflammatory Bowel Disease
Inflammatory bowel diseases (IBD) are group of immune system disorders characterized by a chronic course with remission and relapses.
- Trial name
- NCT02152241
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Maternal Health Services, Outcome Assessment
Long Term Effects Of a Maternal Cash Transfer Experiment
This is a follow-on study to a cluster randomized trial of maternal conditional incentives conducted in Nigeria. This study found that cash transfers, conditional on women obtaining facility-based prenatal, delivery, and…
- Trial name
- NCT05709457
- Testing
- Cash transfer in prior study
- Where
- Nigeria
- Volunteers
- 18,131 people, healthy volunteers welcome
- Sponsor
- RAND
Oppositional Defiant Disorder, Conduct Disorder
Resources to Enhance the Adjustment of Children (REACH)
This continuation study evaluates the long-term outcomes of multimodal, modular interventions with early-onset behavior disordered children and innovative methods to promote the maintenance and extension of treatment effects…
- Conditions
- Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- REACH (NCT00820001)
- Testing
- Booster Treatment, No-Booster, No intervention
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh