Clinical trials: Loop Ileostomy
Incisional Hernia
Efficacy of an Onlay Mesh for Prevention of Incisional Hernia After Loop Ileostomy Closure
The aim of the present study is to determine the efficacy of the placement of an onlay mesh to prevent incisional hernia after loop ileostomy closure in patients with a prior rectal resection for cancer
- Trial name
- ILEOMESH (NCT02896686)
- Testing
- Control CT, Clinical Follow Up, Reinforcement with Light Polypropylene Mesh
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Joan XXIII de Tarragona.
Rectal Neoplasms
Defunctioning Cannula Ileostomy After Lower Anterior Resection of Rectal Cancer
Most surgeons suggest the use of fecal diverting to address the high morbidity and mortality associated with anastomotic leakage (AL) in patients with high risk factors on AL who are undergoing anterior resections.
- Trial name
- NCT01980238
- Testing
- cannula ileostomy, loop ileostomy, LAR
- Where
- China
- Volunteers
- 300 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Ileostomy; Complications
"Dumpling Suture Method" Versus Traditional Suture Method of Protective Loop Ileostomy in Laparoscopic Anterior Rectal Resection With Specimen Extraction Via Stoma: a Retrospective Comparative Study
Natural Orifice Specimen Extraction Surgery (NOSES), which involves obtaining specimens from the abdominal cavity without any incisions, has attracted much attention in recent years, and it has been widely popularized in the…
- Trial name
- NCT06010043
- Testing
- Suturing of ileostomy using "Dumpling suture method", Suturing of ileostomy using Traditional suture method
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Ileostomy; Complications
Stimulation of Efferent Loop Prior to Ileostomy Closure
The aim of this study is to compare postoperative ileus between stimulated and unstimulated patients prior to ileostomy closure.
- Trial name
- NCT01881594
- Testing
- Procedure/Surgery
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Surgical Site Infection (SSI), Ileostomy Closure
Linear Versus Purse String Skin Closure at Loop Ileostomy Reversal.
This study is a randomized controlled trial designed to compare two commonly used skin closure techniques-linear closure and purse-string closure-after loop ileostomy reversal surgery.
- Conditions
- Surgical Site Infection (SSI), Ileostomy Closure, Surgical Technique Comparison
- Trial name
- NCT07573423
- Testing
- Linear Skin Closure, Purse-String Skin Closure
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Ileostomy, Ileostomies
B-suture Ileostomy in Clinical Practice: a Retrospective, Single-center, Propensity Score-matched Study
OBJECTIVE: The purpose of this study was to introduce a new temporary ileostomy modality, the B-suture ileostomy, and to compare its technical advantages in comparison with conventional ileostomy.
- Conditions
- Ileostomy, Ileostomies, Loop Ileostomies
- Trial name
- NCT05915052
- Testing
- B-type suture ileostomy, the traditional ileostomy
- Where
- China
- Volunteers
- 185 people
- Sponsor
- Northern Jiangsu People's Hospital
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Loop Ileostomy, Colorectal Disorders
Quadratus Lumborum Block : Local Anesthesia Versus Placebo
Opioid analgesics have many side effects. Quadratus lumborum (QL) block is one kind of regional nerve block that can reduce the side effects of opioid analgesics.
- Trial name
- NCT03411096
- Testing
- Quadratus lumborum block using ropivacaine, Quadratus lumborum block with normal saline
- Where
- South Korea
- Volunteers
- 57 people
- Sponsor
- Kyungpook National University Hospital
Ileostomy - Stoma, Ileostomy; Complications
Stimulation of the Efferent Loop Before Loop Ileostomy Closure
The purpose of the study is to determine the impact of the efferent loop stimulation of a loop ileostomy prior to closure on postoperative complications such as ileus and hospital stay
- Conditions
- Ileostomy - Stoma, Ileostomy; Complications, Stoma Ileostomy, Ileus Paralytic
- Trial name
- NCT03424447
- Testing
- efferent limb stimulation
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Hospital de Basurto
Ileostomy
Early Temporary Stoma Closure After Proctectomy
We conducted a prospective randomized study to evaluate the results of early closure of temporary loop ileostomy at eight days in comparison with late closure at two months, after elective rectal resection with low pelvic…
- Trial name
- NCT00428636
- Testing
- ileostomy
- Where
- 3 sites in France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Incisional Hernia, Surgical Site Infection
Prophylactic Mesh Reinforcement for Stoma Closure
In the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection …
- Conditions
- Incisional Hernia, Surgical Site Infection, Postoperative Pain, Hospital Stay, Length of Stay in Hospital From Surgery to Discharge
- Trial name
- OASIS (NCT06157645)
- Testing
- Prolene mesh
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Ileostomy - Stoma
Loop Ileostomy Closure as a 23-hour Stay Procedure, a Multi-center Randomized Controlled Trial
The purpose of this study is to assess the safety and feasibility of ileostomy closure performed in a 23 hours hospitalization setting, using a multi-center, open-label, randomized controlled trial comparing patients being…
- Trial name
- ILEO (NCT03941522)
- Testing
- Early discharge from hospital
- Where
- 2 sites in Canada
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Diverticular Disease of Colon, Colostomy - Stoma
ARES Trial: Approach to Resection and Evaluation in Severe Diverticulitis
This observational study was conducted across five surgical centers in Italy, including both academic and community hospitals, from January 2017 to December 2022.
- Conditions
- Diverticular Disease of Colon, Colostomy - Stoma, Loop Ileostomies
- Trial name
- ARES (NCT07094594)
- Where
- Italy
- Volunteers
- 578 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Ileostomy; Complications
The Protective Role of GABA Stimulation Before Ileostomy Closure
The goal of this clinical trial is to explore whether preoperative stimulation of the distal limb of the ileostomy loop with gamma aminobutyric acid (GABA) could effectively reduce the incidence of complications after ileostomy…
- Trial name
- NCT05905393
- Testing
- preoperative stimulation of the efferent loop with GABA before ileostomy closure surgery, preoperative stimulation of the efferent loop with only physiological saline
- Volunteers
- 80 people
- Sponsor
- Qilu Hospital of Shandong University
Rectal Cancer
Efficacy of Stimulation of the Efferent Loop and Rehabilitation of the Pelvic Floor in the Quality of Life of Patients Who Underwent Anterior Resection of the Rectum (ENESP): Randomized Clinical Trial
Many of the patients operated with sphincter preservation will present an alteration of bowel function and defecation. This dysfunction is variable in its symptoms and severity, and manifests itself in the form of urgency…
- Trial name
- ENESP (NCT04569331)
- Testing
- Stimulation of efferent loop, Rehabilitation pelvic floor
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Althaia Xarxa Assistencial Universitària de Manresa
Loop Ileostomy
Prevention of Hernia After Loop Ileostomy Reversal
PHaLIR is a prospective, double-blinded randomized study in which patients planned for stoma reversal after rectal cancer surgery are randomized between retro muscular mesh Ultrapro Advanced or standard treatment without mesh.
- Trial name
- PHaLIR (NCT03720262)
- Testing
- Mesh reinforcement, No reinforcement
- Where
- 4 sites in Sweden
- Volunteers
- 208 people
- Sponsor
- Karolinska Institutet
Ileostomy - Stoma, Ileus
Efferent Loop Stimulation Previous to Ileostomy Closure. Ileostim Trial.
The loop ileostomy is an effective method used to bypass faecal contents and reduce the sequelae of possible anastomotic leakage.
- Conditions
- Ileostomy - Stoma, Ileus, Rectal Cancer, Surgical Complication
- Trial name
- Ileostim (NCT05302557)
- Testing
- Ileostomy stimulation
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Universidad de León
Rectal Neoplasms
Virtual Ileostomy Versus Conventional Loop Ileostomy
This study aimed at comparing the Comprehensive Complication Index (CCI), readmission rates, postoperative hospitalization days, duration of bearing the stoma (months), hospitalization costs, the number of hospitalizations with…
- Trial name
- NCT05985252
- Testing
- Virtual ileostomy, Diverting ileostomy
- Where
- 2 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Rectal Neoplasm
Loop Ileostomy Closure:Stapled or Hand-sewn Anastomoses? Suture or Mesh Closure of the Stoma Site?
There are severel problems associated with the closing of a temporary loop-ileostomy after surgery for rectal cancer. The purpose of this study is to answer two questions: 1.
- Trial name
- LISTO (NCT02669992)
- Testing
- Stapled or Hand-sewn anastomosis, Mesh or suture stoma site closure
- Where
- 11 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska University Hospital
Postoperative Ileus, Colorectal Cancer Control and Prevention
Implementation of an Efferent Loop Stimulation Protocol Prior to Ileostomy Closure at La Paz University Hospital
Stoma creation is a common surgical procedure, employed in certain contexts within general surgery, particularly in colorectal and emergency surgery.
- Conditions
- Postoperative Ileus, Colorectal Cancer Control and Prevention, Stoma - Ileostomy
- Trial name
- NCT06974500
- Testing
- Daily efferent limb stimulation for at least two weeks prior to surgery using saline solution and a thickering agent
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- Hospital Universitario La Paz