Clinical trials: Low Back
Non Specific Low Back Pain
AI-Enhanced Telerehabilitation Program Using Automated Video Analysis and Personalized Feedback on Pain, Disability, Mobility, Endurance, for Chronic Non-Specific Low Back Pain in College Students.
This study tests whether an artificial intelligence (AI)-enhanced telerehabilitation program can effectively treat chronic non-specific low back pain in college students.
- Trial name
- NCT07145996
- Testing
- AI Based Exercises, Standard Telerehabilitation
- Where
- India
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Nonspecific Chronic Low Back Pain
Body and the Brain: Cortical Reactivity and Cognitive-Affective Regulation to Experimental Pain.
The purpose of this cross-sectional study is to compare cortical reactivity and cognitive-affective regulation in response to experimental pain between healthy controls and individuals with non-specific chronic low back pain.
- Trial name
- NCT07896785
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Low Back Pain
Alberta Back Care Pathway (ABCp)
Every year, the pain, disability, addiction, and expense associated with LBP increase in Alberta. This escalation is largely because most people with LBP seek care from family physicians who are unable to provide effective…
- Trial name
- ABCp (NCT05452876)
- Testing
- ABCp, Usual Care
- Where
- Canada
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Low Back Pain, Mechanical, Chronic Pain
The Long Term Effects of Online Therapeutic Neuroscience Education in Patients With Chronic Low Back Pain
This study aims to evaluate the effects of online Therapeutic Neuroscience Education (TNE) combined with a 6-week conventional physiotherapy program on pain, disability, kinesiophobia, functionality, treatment expectations, and…
- Trial name
- NCT06847763
- Testing
- Therapeutic Neuroscience Education, Conventional Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Chronic Low Back Pain (CLBP), Physical Therapy
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
The purpose of this research study is to investigate whether a single administration of psilocybin can improve interoceptive awareness (awareness of bodily sensations) in individuals with chronic low back pain undergoing physical…
- Conditions
- Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
- Trial name
- NCT07306364
- Testing
- Psilocybin 10 mg, Psilocybin 25 mg, Niacin 100 mg
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yale University
Low Back Pain, Recurrent, Healthy
Effects of Sleep Disruption on Drug Response
The central scientific premise of the proposed study is that sleep disruption (SD) will influence individuals' subjective response to blinded medication administration.
- Trial name
- NCT03680287
- Testing
- Within-Subject test of blinded study medication
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Low Back Pain, Spondylolisthesis
Evaluation of Balance Using the Biodex Balance System Among Different Subcategories of Low Back Pain
this study aims to evaluate balance using the biodex balance system among patients with spondylosis, spondylolisthesis, and lumber disc prolapse.
- Conditions
- Low Back Pain, Spondylolisthesis, Spondylosis Lumbar, Balance Assessment
- Trial name
- Biodex (NCT07242976)
- Testing
- Assessment of balance will be measured by The Biodex Balance System (BBS) which computes Postural Stability key indices: the medial-lateral stability index (MLSI), anterior-posterior stability index
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Migraine, Musculoskeletal Pain
Overlapping Pain Trajectory Study
The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1.
- Conditions
- Migraine, Musculoskeletal Pain, Functional Abdominal Pain Disorders, Chronic Pain
- Trial name
- COPC (NCT05752396)
- Testing
- Conditioned Pain Modulation, Offset Analgesia, Spatial Summation
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Low Back Pain
The Effect of Exercise on Motion Perception and Fear in Low Back Pain
Nonspesific low back pain (NLBP), which negatively affects functionality, activity participation, and financial situation, is now one of the leading causes of disability in the world.
- Trial name
- NCT05433311
- Testing
- Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Low Back Pain, Healthy Volunteer
Evaluation of the Comfort Increase Provided by an Additional Foam Pad on a Lumbar Belt and Its Biophysical Impact
The spine is the central musculoskeletal system of the back. It carries and supports a major part of the body weight and ensures simultaneously the trunk's mobility, particularly the mobility of the lumbar spine and the head's…
- Trial name
- CONFORT (NCT07355790)
- Testing
- MRI, MRI evening 2, MRI evening 1
- Where
- France
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Low Back Pain
Multi-Omics Characterization of Percutaneous Electrolysis in Low Back Pain
Low back pain is a highly prevalent musculoskeletal condition and is frequently associated with structural and functional alterations of the lumbar multifidus muscle.
- Trial name
- MOPE-LBP (NCT07524010)
- Testing
- Percutaneous electrolysis
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Low Back Pain, Pregnancy
The Effect of Kinesio Taping During Labor on Low Back Pain, Vaginal Birth Self-Efficacy, Postpartum Comfort Perception, and Newborn Apgar Scores
The Kinesio Taping® technique and Kinesio Tex® tape were invented by Japanese chiropractor and acupuncturist Dr. in 1973. Developed by Kenzo Kase.
- Conditions
- Low Back Pain, Pregnancy, Midwifery, Birth Self-efficacy
- Trial name
- kinesio tape (NCT07459231)
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ege University
Low Back Pain, Musculoskeletal Pain
Soft Active Back Exosuit to Reduce Workplace Back Pain
The goal of this clinical trial is to determine if a wearable back exosuit can make it safer and easier for workers who bend, lift, and lower objects in an industrial setting.
- Conditions
- Low Back Pain, Musculoskeletal Pain, Low Back Injury
- Trial name
- NCT05802914
- Testing
- Back Exosuit
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Wyss Institute at Harvard University
Low Back Pain, Neck Pain
Wearable Spine Assessment in Adults With and Without Low Back or Neck Pain
This is a single-site, prospective, observational, single-visit feasibility and validity study. Adult participants with and without low back or neck pain will be screened, consented, and enrolled to undergo a structured…
- Trial name
- AxiSens-01 (NCT07643207)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Ashkan Vaziri
Low Back Pain
Back Beliefs Among the General Population
In the current study we aim to evaluate the effects of a short educational video on improving the belief that "the back is fragile and needs to be protected" among the German speaking Swiss general population.
- Trial name
- NCT06104995
- Testing
- Interventional video, Control video
- Where
- Switzerland
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Bern University of Applied Sciences
Non-specific Chronic Low Back Pain
Relationships Between Muscle Activity, Soft Tissue Changes, and Movement Strategies in Individuals With Chronic Low Back Pain
This study aims to explore, in patients with chronic non-specific low back pain (cnsLBP), the relationships between lumbar muscle activity, structural and morphological characteristics of the paraspinal muscles, and movement…
- Trial name
- E-LBP (NCT07806253)
- Testing
- Supervised Progressive Walking Test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Discogenic Pain, Back Pain
VIA Disc NP Registry
Registry is to observe and trend patterns of care and outcomes for patients treated with VIA Disc NP.
- Conditions
- Discogenic Pain, Back Pain, Back Pain, Low
- Trial name
- NCT04652687
- Testing
- VIA Disc NP (HCT/P)
- Where
- 32 sites in United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
Chronic Low-back Pain, Myofascial Pain
Ultrasound Imaging for Myofascial Pain
The goal of this observational study is to develop and validate a biomarker for lumbar myofascial pain (MP) based on ultrasound obtained measurements of the lumbar muscles and fascia.
- Trial name
- NCT05928884
- Testing
- There is no intervention. It is a phenotyping study only
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Low Back Pain, Low Back Pain, Mechanical
Effects of Mental Participation During Lumbar Stabilization and Neuromuscular Electrical Stimulation in Chronic Non-Specific Low Back Pain
This study was conducted to investigate the effects of incorporating synchronized voluntary muscle activation and active motor engagement during neuromuscular electrical stimulation (NMES) into a lumbar stabilization exercise…
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, NMES, Mental Perception
- Trial name
- NCT07857642
- Testing
- Exercise + NMES, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Back Pain, Back Pain Lower Back
Use of Ultrasound Imaging in Confirming Osteopathic Spinal Diagnosis
In the field of Osteopathic Medicine, diagnosis of potential areas of dysfunction are diagnosed by the physician using their hands and expertise in noticing subtle differences in symmetry, tone, swelling etc..
- Conditions
- Back Pain, Back Pain Lower Back, Back Pain Lower Back Chronic, Back Pain With Radiation
- Trial name
- NCT07858071
- Testing
- Spinal Ultrasound
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System