Clinical trials: Low Cost
Cleft Lip Repair
Pilot Study of Smartphone -Based AI Assisted Ultrasound Guided Infraorbital Nerve Block in Pediatric Cleft Lip Repair
It's prospective single blinded randomized multi-center trial of 120 infant scheduled for primary unilateral cleft lip repair .
- Trial name
- NCT07232914
- Testing
- Infraorbital Nerve Block
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Yaws; Cutaneous, Cutaneous Ulcer
An Accessible Low-cost Plant Treatment for Cutaneous Ulcers
In a search for accessible treatment options, plant medicines used by different communities in Papua New Guinea have been tested to identify the sap of the tree, Ficus septica, as a promising antibacterial agent in vitro.
- Conditions
- Yaws; Cutaneous, Cutaneous Ulcer, Yaws
- Trial name
- NCT04453124
- Testing
- Topical antiseptic treatment
- Where
- 2 sites in Papua New Guinea
- Volunteers
- 150 people
- Sponsor
- Oriol Mitja
Multiple Sclerosis
Virtual Reality for Upper Limb Rehabilitation in Multiple Sclerosis
This study is aimed to test the efficacy and feasibility of an immersive virtual reality (VR) rehabilitation programs to improve upper-limb motor functions in 24 patients with multiple sclerosis (pwMS), characterized by moderate…
- Trial name
- NCT04027491
- Testing
- Virtual Reality
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- University of Cagliari
Cognitive Dysfunction, Dementia
ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings
Our study objective is to widely implement and evaluate a user-centered, scalable, electronic health record (EHR)-linked strategy for the routine detection of cognitive decline among diverse primary care settings.
- Trial name
- NCT04852601
- Testing
- ToolboxDetect
- Where
- United States
- Volunteers
- 35,403 people
- Sponsor
- Northwestern University
HIV-1-infection
Kenya HIV Self-Testing in PrEP Delivery
In a three-arm, randomized trial, the investigators will test the use of HIV-1 self-testing to decrease the frequency and burden of clinic visits for PrEP while resulting in equivalent PrEP adherence and HIV testing.
- Trial name
- NCT03593629
- Testing
- 6-month PrEP + blood-based HIV self-test, 6-month PrEP + oral fluid HIV self-test
- Where
- Kenya
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University of Washington
Tobacco Smoking, Alcohol-Related Disorders
Intervention to Increase Intention to Change Alcohol/Tobacco Use in Veterans With Chronic Disease
Many Veterans who have chronic conditions like cardiovascular disease or diabetes smoke or drink too much alcohol, which can worsen the condition.
- Trial name
- MINDSET (NCT07039175)
- Testing
- MINDSET, Usual Care
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- VA Office of Research and Development
Newborn Hypothermia
Efficacy of Celsi Warmer for the Management of Hypothermic Newborns
The purpose of the study is to evaluate the efficacy of a novel low-cost warming device to provide thermal care for newborn babies with hypothermia in low-resource hospitals.
- Trial name
- NCT06000826
- Testing
- Celsi Warmer
- Where
- Tanzania
- Volunteers
- 90 people
- Sponsor
- William Marsh Rice University
Low Back Pain
Cost- Effectiveness of a Face-to-Face Rehabilitation Program vs an Telemedicine Program in Chronic Low Back Pain
Perform a cost-utility analysis in patients with chronic low back pain through electroanalgesia treatment and exercises administered by telemedicine program versus face-to-face program
- Trial name
- NCT04266366
- Testing
- Face-to-Face Rehabilitation program, Telemedicine program
- Where
- Spain
- Volunteers
- 540 people
- Sponsor
- Universidad de Almeria
Cancer, Thrombosis
Anticoagulation Length in Cancer Associated Thrombosis
This is a two year, multicentre, mixed methods feasibility study including a randomised controlled two-arm interventional trial, a nested qualitative study, focus groups and a United Kingdom (UK) wide survey exercise.
- Conditions
- Cancer, Thrombosis, Venous Thromboembolism, Deep Vein Thrombosis
- Trial name
- ALICAT (NCT01817257)
- Testing
- Low Molecular Weight Heparin (LMWH)
- Where
- 5 sites in United Kingdom
- Volunteers
- 2 people
- Sponsor
- Cardiff University
Oral Cancer
Low-cost Enabling Technology for Image-guided Photodynamic Therapy (PDT) of Oral Cancer Cancer.
Oral cancer in India affects mostly those from the lower socioeconomic groups, due to a higher exposure to risk factors such as the use of tobacco, zarda, khaini, chewing gutka, mawa, and kharra, which are all dry mixtures of…
- Trial name
- UH3-India (NCT03638622)
- Testing
- Photodynamic Therapy
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Postpartum Hemorrhage
Kenya: The Barriers and Facilitators of Scaling up the Ellavi UBT for Postpartum Hemorrhage
The purpose of this implementation research study is to generate evidence that informs the successful uptake and adoption of the Ellavi Uterine Balloon Tamponade (UBT) within Kenyan postpartum hemorrhage (PPH) management…
- Trial name
- NCT04502173
- Testing
- Ellavi UBT
- Where
- Kenya
- Volunteers
- 200 people
- Sponsor
- PATH
Simulation Based Medical Education, Tracheal Intubation
Low-Cost Model Versus Airway Part-Task Trainer for Flexible Bronchoscope-Guided Tracheal Intubation Training
Background: Awake flexible bronchoscope-guided tracheal intubation (FBTI) is crucial in managing challenging airway situations. As the gold standard for difficult airway management, FBTI is essential for anesthesiologists to…
- Conditions
- Simulation Based Medical Education, Tracheal Intubation, Medical Residents
- Trial name
- RAN (NCT06959953)
- Testing
- Low-cost model, Airway Part-task Trainer
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Lebanese American University
Low Back Pain
The Costs and Effectiveness of Cognitive Functional Therapy for People with Persistent Low Back Pain in Coventry.
Previous studies have shown Cognitive Functional Therapy (CFT) results in sustained clinically important improvements compared to a variety of interventions for persistent low back pain (LBP).
- Trial name
- NCT06161753
- Testing
- Cognitive Functional Therapy
- Where
- United Kingdom
- Volunteers
- 61 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Sickle Cell Disease, Sickle Cell Trait
Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada
Sickle cell disease (SCD) is an inherited blood disorder associated with acute illness and organ damage. In high resource settings, early screening and treatment greatly improve quality of life.
- Conditions
- Sickle Cell Disease, Sickle Cell Trait, Beta-Thalassemia, Sickle Cell-Beta Thalassemia
- Trial name
- NCT05506358
- Testing
- High performance liquid chromatography, Automated sickling test, HbS solubility test
- Where
- 3 sites in Canada, Nepal
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Childhood Immunization Completion, Childhood Immunization Dropout
Low Cost Interventions to Improve Adherence to Childhood Immunization Schedule
The objective of the study was to assess the effect of 1) redesigned immunization card, 2) center-based education to mothers, and 3) redesigned card with center-based education to mothers, provided at DPT1, on DPT3 completion in…
- Conditions
- Childhood Immunization Completion, Childhood Immunization Dropout, Immunization Card, Center Based Education
- Trial name
- NCT00602056
- Testing
- Redesigned immunization card, Center based education to mothers/caregivers, Redesigned immunization card with center based education to mother/caregivers
- Where
- Pakistan
- Volunteers
- 1,506 people
- Sponsor
- University of Alabama at Birmingham
Optical Coherence Tomography of Retina
Comparative Study of High Performance Low-Cost Optical Coherence Tomography
The purpose of this study is to complete performance testing of our custom optical coherence tomography (OCT) device to verify it can deliver retinal images of similar quality to a commercial OCT device.
- Trial name
- NCT05530460
- Testing
- retinal imaging with low-cost OCT device, retinal imaging with commercial OCT device
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Duke University
Colostomy Stoma, Ileostomy - Stoma
Needle-Aspirated Compression Dressing Following Ostomy Reversal
Negative pressure wound dressings have been studied and shown to have applications in decreasing rates of surgical wound infections.
- Conditions
- Colostomy Stoma, Ileostomy - Stoma, Surgical Site Infection, Wound Complication
- Trial name
- NCT03703661
- Testing
- Needle-Aspirated Negative Pressure Dressing, Control
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Low Back Pain
FAcet-joint Injection Clinical and Cost-effective Trial
Lumbar facet-joints are small, paired joints in the low back that provide stability, integrity and flexibility of movement to the spine.
- Trial name
- FACET (NCT03339362)
- Testing
- Active Procedure
- Where
- 3 sites in United Kingdom
- Volunteers
- 9 people
- Sponsor
- Barts & The London NHS Trust
Open Tibia Fracture
Low-cost Negative Pressure Wound Therapy vs Standard Dressings for Gustilo IIIb Tibial Fractures (Bukavu Pilot RCT)
Negative-pressure wound therapy (NPWT) is widely used in the management of acute and chronic wounds, but commercial systems are costly and may be inaccessible in low-resource settings.
- Trial name
- BukavuNPWTRC (NCT07790991)
- Testing
- intervention2: standard wound dressing, Intervention1: Low-cost NPWT
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 66 people
- Sponsor
- Université Catholique de Bukavu
Depression
LTP Plus Dads-Partner Inclusive Intervention for Depressed Fathers in Pakistan
The aim of this study is to support and equip fathers and mothers with cognitive behavioral tools and knowledge about child development to be effective in their role as co-parent and partner, leading to improvement in paternal…
- Trial name
- LTP+Dads (NCT05036720)
- Testing
- LTP+Dads, LTP+ Optional mother component
- Where
- Pakistan
- Volunteers
- 2,884 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Living and Learning