Clinical trials: Low Vision Blindness
Cortical Visual Impairment, Visual Function
Exosomes Effect on Visual Function in CVI
The goal of this observational study is to learn about the effects of nazally applied exosome treatment on visual functions in children with Phase 1 Cerebral visual impairment (CVİ).
- Trial name
- NCT07492966
- Testing
- Molecularly matched therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Hatice Semrin Timlioglu İper
Cerebral Palsy, Cortical Visual Impairment
Cortical Visual Impairment and Visual Attentiveness
This study will investigate the effect of enhanced visual and cross-modal environments upon the visual attentiveness of multiply handicapped children diagnosed with Cerebral Palsy (CP) and Cortical Visual Impairment (CVI).
- Trial name
- NCT00342108
- Testing
- cross-modal sensory stimulation
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Trauma, Infections
Ophthalmological Emergencies and COVID-19 Pandemia
To analyze how the COVID 19 pandemia has affected the patient's accesses to the Ophthalmological Emergency Department of a tertiary referral center in northern Italy, during the lockdown period.
- Conditions
- Trauma, Infections, Vision; Loss, Both Eyes
- Trial name
- NCT05065788
- Testing
- data collection
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Università degli Studi dell'Insubria
Cortical Blindness
Multisensory Rehabilitation of Vision Loss After Cortical Damage
Damage to visual cortex on one side of the brain frequently produces a profound and permanent blindness in contralesional space (hemianopia), a debilitating condition that causes enormous suffering for patients and their families.
- Trial name
- NCT07659691
- Testing
- Multisensory Rehabilitation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Macular Degeneration, Wet Macular Degeneration
Aflibercept After Ranibizumab in Exudative Age-related Macular Degeneration
The purpose of the current study is to evaluate the ability of Eylea to induce a regression of PED height on patients previously extensively treated by Lucentis.
- Conditions
- Macular Degeneration, Wet Macular Degeneration, Retinal Degeneration, Retinal Diseases
- Trial name
- ARI2 (NCT02157077)
- Testing
- Aflibercept
- Where
- 9 sites in France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Disabilities, Visual Impairment and Blindness (Excl Colour Blindness)
Study Protocol: The Jerte Valley as an Inclusive Outdoor Classroom. Smart and Active Tourism.
To promote the inclusion of people with disabilities, an outdoor intervention will be conducted involving physical activities with adolescents with and without disabilities.
- Trial name
- NCT07609459
- Testing
- Rafting, canoeing and kayaking, Divulgation
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Extremadura
Anterior Ischemic Optic Neuropathy
PDE5 Inhibitor Use and Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)
The primary objective of this study is to determine whether the use of PDE5 inhibitors (vardenafil, sildenafil, or tadalafil) increases the risk for the development of NAION.
- Trial name
- NCT00867815
- Testing
- Diagnostic procedures
- Where
- 13 sites in United States, Australia and 1 more
- Volunteers
- 10 people
- Sponsor
- Bayer
Vision Loss Partial, Hemianopia
Effect of Visual Retraining on Visual Loss Following Visual Cortical Damage
This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and…
- Conditions
- Vision Loss Partial, Hemianopia, Hemianopia Homonymous, Quadrantanopia
- Trial name
- NCT05098236
- Testing
- Training in the Blind Field, Training in the Sighted Field
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Low Vision
Wearable Echolocation Aids Using Parametric Sound
The objective of this study is to study a novel device designed to aid patients with impaired vision to safely navigate their environment.
- Trial name
- NCT07218991
- Testing
- Wearable Echolocation Device
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cerebral Visual Impairment
Neurodevelopmental Outcomes in Cerebral Visual Impairment
Cerebral visual impairment (CVI) is one of the leading causes of pediatric visual impairment and negatively impacts the development of motor, language, and cognitive skills.
- Trial name
- CVI-ND (NCT07212010)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Homonymous Hemianopsia
Ongoing Effect of Expansion Prisms Following the Discontinuation of Use on Visual Field Enlargement and Retrograde Ganglion Cell Degeneration in Homonymous Hemianopia Patients
The goal of this observational study is to learn about the long-term effects of Pelli prism in Hemianopia patients who take Prisms for awareness of the area they cannot see.
- Trial name
- NCT06674369
- Testing
- Peli prism for hemianopia
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Okan University
Blindness, Visual Impairment
The Impact of the Years of Blindness on Sleep and Dreaming Processes and the Relationships With Spatial Abilities
This study aims to assess the impact of blindness on sleep and dreaming processes and the relationship with spatial perceptual performance, examining the link with clinical and psychological indices, neurobiological features, and…
- Trial name
- NCT06631807
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istituto Italiano di Tecnologia
Diabetic Retinopathy, Blindness
Diabetic Retinopathy Study (DRS)
To determine whether photocoagulation helps prevent severe visual loss from proliferative diabetic retinopathy. To determine whether a difference exists in the efficacy and safety of argon versus xenon photocoagulation for…
- Trial name
- NCT00000160
- Testing
- Xenon Photocoagulation, Argon Photocoagulation, Photocoagulation
- Sponsor
- National Eye Institute (NEI)
Cerebral Visual Impairment, Refractive and Accommodative Disorders
Babies in Glasses; a Feasibility Study.
This is a feasibility study to begin investigating the possibility that early use of near vision glasses will improve vision in infants at risk of Cerebral Visual Impairment (CVI), leading to further improvement in other areas of…
- Conditions
- Cerebral Visual Impairment, Refractive and Accommodative Disorders, Hypoxic-Ischemic Encephalopathy, Premature Birth
- Trial name
- BiG (NCT05048550)
- Testing
- Near vision spectacles
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Blindness and Low Vision
A Pilot Study Comparing Performance of Blind Participants on 12 Tasks, With and Without the ARIA Device
Summary The environment in which we live, play and travel is primarily built by and for people with sight. Navigating the sighted world with blindness can be exhausting, as it involves disorientation, social isolation, increased…
- Trial name
- NCT06477809
- Testing
- ARIA Glasses ( Augmented Reality in Audio )
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- ARIA Research Pty Ltd
Low Vision, Central Visual Impairment
Vision Rehabilitation Training With Multimodal Feedback in Central Vision Loss
Central vision loss from macular degeneration creates blind spots that impair reading, face recognition, and navigation. Individuals must learn to use peripheral vision, requiring retraining of eye movements.
- Conditions
- Low Vision, Central Visual Impairment, Macular Degeneration
- Trial name
- NCT07577219
- Testing
- eccentric viewing training with biofeedback
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- New England College of Optometry
Dry Age-related Macular Degeneration, Vision Impairment and Blindness
Vision Improvement for Legally Blind Dry AMD Patients
This retrospective observational study is intended to assess the feasibility of using a nonsignificant risk device for vision improvement for legally blind dry AMD patients.
- Trial name
- NCT04875234
- Testing
- Clear-K Low Vision Aid Treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Optimal Acuity Corporation
Cataract
China OLIMPICS: China Ophthalmic Learning and Improvement Initiative in Cataract Surgery Trial
This is a prospective, investigator-masked randomised controlled education-intervention trial of intense simulation-based surgical education plus conventional training versus a current six-week standard training course.
- Trial name
- NCT03458442
- Testing
- Simulation-based surgical training, Standard surgical training
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Sun Yat-sen University
Central Visual Impairment
Peripheral Reading
The purpose of this study is to evaluate reading performance in the visual periphery by simulating central vision loss using a computer-controlled gaze-contingent display with an eye tracker.
- Trial name
- NCT03640130
- Testing
- Gaze-contingent text enhancement
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Houston
Low Vision Blindness
Audio-guided Home Physical Activity to Support People With Low Vision: Physical Performance and Quality of Life
The aim of the project is to investigate the effectiveness of a home training managed through audio-guides in comparison to a classic supervised training on the physical and psychological parameters of patients with severe low…
- Trial name
- NCT05956730
- Testing
- Physical Activity (AUD), Physical Activity (SUP)
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA