Clinical trials: Low-Level Laser Therapy
Knee Osteoarthritis
Immediate Effects of High-intensity Laser Therapy on Knee Joint Position Sense and Knee Muscle Strength in Patients with Knee Osteoarthritis
The goal of this clinical trial is to compare whether HILT versus Sham-HILT is effective to reduce pain, improve knee joint position sense, and knee muscle strength.
- Trial name
- HILT on KOA (NCT06632119)
- Testing
- high-intensity laser therapy
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Melasma, Post-acne Hyperpigmentation
Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES
The goal of this clinical trial is to evaluate the efficacy and safety of a combination serum containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES when used as a moisturizer after QS-Nd:YAG 1064 nm low-fluence laser…
- Trial name
- NCT07121439
- Testing
- a combination serum containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES, 2% hydroquinone cream
- Where
- Indonesia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Injectable Plasma-rich Fibrin Versus Low-Level Laser Therapy on Othodontic Movement
Assessment of Different Orthodontic Tooth Movements Assisted With Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
The present prospective clinical study will be undertaken for assessment of the effect of application of Injectable plasma-rich fibrin versus Low-Level Laser Therapy onthe rate of different orthodontic tooth movements,
- Trial name
- NCT05966987
- Testing
- Low-level Laser Therapy vs. Injectable Platelets-rich Fibrin
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Sensitivity, Tooth Bleaching
Photobiomodulation Before or After Tooth Whitening
The objective is to evaluate the effect of photobiomodulation (PBM) applied before or after in-office tooth whitening in reducing tooth sensitivity (TS) and color change.
- Conditions
- Tooth Sensitivity, Tooth Bleaching, Laser Therapy
- Trial name
- NCT06518629
- Testing
- Photobiomodulation with low power laser
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Hydration, Carbon-dioxide Laser
Effectiveness and Safety of a Hydrating Gel Containing Polyvinyl Pyrrolidine, Algin and Hyaluronic Acid Applied After and Without Fractional CO₂ Laser Therapy
The purpose of this interventional study is to evaluate the effectiveness and safety of a hydrating gel containing aqua, carrageenan, polyvinyl pyrrolidone, algin, gellan gum, and hyaluronic acid.
- Conditions
- Hydration, Carbon-dioxide Laser, Laser Therapy, Hydrogel
- Trial name
- NCT07639151
- Testing
- CO2 Fractional Laser, Hydrogel
- Where
- Indonesia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Postoperative Pain
Evaluation the Effect of Using Preoperative Ibuprofen Versus Low Level Laser Therapy on Inferior Alveolar Nerve Block
Acute apical periodontitis (AAP) is an inflammatory condition of the periapical tissues of the periodontium, usually resulting from irreversible pulpitis and pulpal necrosis.
- Trial name
- NCT05479175
- Testing
- Ibuprofen, Diode laser, Nonactive Diode laser
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Shoulder Pain, Neck Pain
Low Level Laser Light Therapy and Chronic Neck and Shoulder Pain
The purpose of this study was to determine whether the application of low level laser light therapy to the neck and shoulder region is effective in reducing chronic neck and shoulder pain of musculoskeletal origin.
- Conditions
- Shoulder Pain, Neck Pain, Musculoskeletal Pain, Musculoskeletal Strain
- Trial name
- NCT00929305
- Testing
- Erchonia PL2000
- Volunteers
- 100 people
- Sponsor
- Erchonia Corporation
Vein, Varicose
Effect of Walking to the Operating Room on Preoperative Anxiety
The operating room environment can be a source of anxiety for the patient, including in the context of outpatient surgery for which anxiolytic medication is rarely used.
- Trial name
- NCT04908527
- Testing
- Walking to OR
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- University of Liege
Peri-implant Mucositis
Adjunctive Diode Laser Therapy for Peri-Implant Mucositis
Peri-implant mucositis is an inflammatory condition affecting the soft tissues surrounding dental implants. Conventional non-surgical treatment is primarily based on mechanical removal of bacterial biofilm, although complete and…
- Trial name
- NCT07895667
- Testing
- Conventional Non-Surgical Treatment, FOX III Diode Laser Therapy
- Volunteers
- 144 people
- Sponsor
- Universidad Europea de Valencia
Benign Solitary Solid, Cystic Thyroid Nodules
Laser Therapy of Benign Thyroid Nodules
Nodular goitre is common in the general population and less than 5% of the patients who undergo surgery for solitary thyroid nodules have cancer, in absence of clinical suspicion.
- Trial name
- NCT00150150
- Testing
- Interstitial laser photocoagulation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Odense University Hospital
Episiotomy; Complications, Laceration
Comparison Low-Level Laser Therapy With Cryotherapy in Parturients With Laceration and/or Episiotomy on Pain Reduction
The changes that occur during pregnancy can lead to symptoms and complaints for women. Vaginal delivery has several benefits for both the mother and baby; however, during labor, some injuries may occur, such as lacerations and…
- Trial name
- CL (NCT06370910)
- Testing
- Low-Level Laser Therapy
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Pain, Perineal Healing
Low-level Laser Therapy in Pain and Perineal Healing in the Immediate Postpartum Period: a Randomized Clinical Trial.
This randomized clinical trial aims to evaluate the effectiveness of low-level laser therapy compared with sham treatment on pain intensity and perineal wound healing quality in the immediate postpartum period.
- Trial name
- LaserPerineal (NCT07480083)
- Testing
- low-level laser therapy
- Where
- Brazil
- Volunteers
- 206 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Thumb Osteoarthritis, Hand Injuries
High-Energy Laser in the Conservative Treatment of Rhizarthrosis
Osteoarthritis (OA) is a degenerative joint disease that can affect the hands and is particularly debilitating when it involves the trapeziometacarpal joint (rhizarthrosis).
- Conditions
- Thumb Osteoarthritis, Hand Injuries, Laser, Exercise
- Trial name
- HLEX-TO (NCT07566507)
- Testing
- THEAL:Ixyon XP (Mectronic, Bergamo, Italy)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Ischemic Stroke
Effectiveness and Safety Trial of a New Ischemic Stroke Treatment Within 24 Hours From Stroke Onset (NEST-2)
The purpose of this pivotal study is to demonstrate safety and effectiveness of the NeuroThera® Laser System (referred to hereafter as NTS) in the treatment of Subjects diagnosed with acute ischemic stroke.
- Trial name
- NCT00419705
- Testing
- NeuroThera® Laser System
- Where
- 58 sites in United States, Germany and 2 more
- Volunteers
- 660 people
- Sponsor
- PhotoThera, Inc
Carpal Tunnel Syndrome
The Effect of High-intensity Laser Therapy in Patients With Carpal Tunnel Syndrome.
The aim of this study is to evaluate the effects of high intensity laser therapy (HILT) on pain, functional status, hand grip strength and median nerve cross-sectional area in ultrasonography in patients with carpal tunnel…
- Trial name
- NCT05678595
- Testing
- high-intensity laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Necmettin Erbakan University
Male Pattern Baldness, Androgenetic Alopecia
Assessing the Safety and Efficacy of a Novel Microneedling and Laser Device for Male Pattern Hair Loss
The purpose of this 24-week study is to see if the SAGA-001 device is safe and effective at helping people with male pattern hair loss. Two different device configurations are being explored as part of this study.
- Conditions
- Male Pattern Baldness, Androgenetic Alopecia, Hair Loss/Baldness, Hair Loss
- Trial name
- CS-SAGA-001 (NCT05970809)
- Testing
- SAGA-001 (A), SAGA-001 (B)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- StimuSIL
Myofacial Pain Syndrome
The Effect of Low Level Laser Therapy (LLLT) in Myofacial Pain Syndrome
Temporomandibular disorders (TMDs) are the major cause of non-dental pain in orofacial area. Laser therapy can be considered as one of the most recent treatment approaches in the field of physiotherapy.
- Trial name
- NCT01417637
- Testing
- Low level laser therapy
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Hidradenitis Suppurativa (HS)
A Single-center, Prospective, Self-controlled, Observational Real-world Study of the Efficacy and Safety of Anti-IL-17A/F Monoclonal Antibody Combined With Non-ablative Dot Laser for the Treatment of Mild to Moderate Hidradenitis Suppurativa
The goal of this clinical trial is to learn if combining an IL-17A/F monoclonal antibody with non-ablative fractional laser therapy works and is safe in patients with mild to moderate hidradenitis suppurativa (HS).
- Trial name
- NCT07554014
- Testing
- IL-17A/F mAb + NAFL
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Melasma, Lichen Planus Pigmentosus
Efficacy of Red Light in the Treatment of Pigmentary Disorders
Pigmentary disorders such as melasma, lichen planus pigmentosus and vitiligo can significantly affect patients' quality of life. Treatment responses are usually slow and typically have limited efficacy.
- Conditions
- Melasma, Lichen Planus Pigmentosus, Vitiligo
- Trial name
- NCT04308421
- Testing
- Red light
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- University of British Columbia
Low Back Pain
High-intensity Laser Therapy and Mulligan Mobilization for Patients With Chronic Nonspecific Low Back Pain
The goal of this clinical trial is to evaluate whether combining high-intensity laser therapy with Mulligan mobilization techniques can effectively treat chronic non-specific low back pain in adult patients aged 18-60 years…
- Trial name
- NCT07556926
- Testing
- High-intensity laser therapy and Mulligan mobilization, Mulligan Mobilization
- Where
- Jordan
- Volunteers
- 50 people
- Sponsor
- Anas Radi Hassan Alashram