Clinical trials: Low-level Light Therapy
Myeloablative Allogeneic Hematopoietic Cell Transplantation, Intraoral Photobiomodulation Therapy
Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation
This is a single center pilot study evaluating intraoral photobiomodulation for the prevention of oral mucositis in patients undergoing myeloablative allogeneic hematopoietic cell transplantation (alloHCT).
- Conditions
- Myeloablative Allogeneic Hematopoietic Cell Transplantation, Intraoral Photobiomodulation Therapy, Oral Mucositis, Mucosal Ulcer
- Trial name
- NCT05335434
- Testing
- THOR LX2.3 with LED Lollipop
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dana-Farber Cancer Institute
Photobiomodulation Therapy
Photobiomodulation and Implant Stability
Objective: The aim of the present study was to address the following questions: does photobiomodulation therapy (PBMT) improve implant stability and affect microbiota around dental implants in the early stage of osseointegration.
- Trial name
- low-laser (NCT04495335)
- Testing
- photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- T.C. Dumlupınar Üniversitesi
Defective; Circulation
Study of Low Level Laser Light Therapy to Improve Blood Circulation in People With Chronic Heel Pain
The purpose of this study is to determine whether low level laser light therapy is effective in increasing local blood circulation in people with chronic heel pain arising from plantar fasciitis.
- Trial name
- NCT01882725
- Testing
- Erchonia HP Scanner (HPS)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Erchonia Corporation
Diabetic Peripheral Neuropathy, Diabetes Mellitus Type 2
Photobiomodulation for Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is a common complication of long-term diabetes, affecting approximately 50 percent of patients.
- Trial name
- PBMT-DPN (NCT07613489)
- Testing
- Photobiomodulation Therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Faisalabad
Diabetes Mellitus, Type 2
Pre-Mix Insulin Lispro Treatment for Type 2 Diabetes Patients Who Consume a Light Breakfast
This study is designed to look at how best to start and then gradually intensify (as needed) the insulin lispro premix regimen in type 2 diabetes patients who consume a light breakfast.
- Trial name
- NCT00664534
- Testing
- Insulin Glargine, Insulin Lispro Premix (mid-mixture and low-mixture)
- Where
- 27 sites in Canada, Egypt and 6 more
- Volunteers
- 344 people
- Sponsor
- Eli Lilly and Company
Sensitivity, Tooth
The Association of CPP-ACPF Associated With LASER in the Treatment of Tooth Sensitivity After at Home Bleaching
Tooth whitening is a procedure that has been increasingly requested by patients around the world, whether at home or in office bleaching. Tooth sensitivity is the main side effect of bleaching.
- Trial name
- NCT05298059
- Testing
- Laser of low frequncy, CPP-ACPF
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Gingival Enlargement
Comparison of the Effect of Ozonized Gel to That of Photobiomodulation Therapy on Wound Healing Following Surgical Gingivectomy
The goal of this clinical trial is to compare the effect of photobiomodulation to ozonized gel on wound healing following gingivectomy procedure on adults.
- Trial name
- NCT07234994
- Testing
- ozonized gel application, photobiomodulation therapy using diode laser
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Mennatullah osama ahmed zaki wahba
Low Back Pain
Photobiomodulation Therapy on Inflammatory Mediators on Low Back Pain
Low back pain (LBP) is ranked as one of the most prevalent health conditions. It is likely that some inflammatory mediators could be associated with pain and disability in these patients.
- Trial name
- NCT03859505
- Testing
- Active PBMT
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Universidade Cidade de Sao Paulo
Choroid, Retina
Effect of Different Intensities of Repeated Low-Level Red-Light Therapy on Choroidal and Retinal Blood Flow Among Adults
The purpose of this clinical trial is to evaluate the effect of different intensities of repeated low-level red-light (RLRL) therapy on the choroidal and retinal blood flow among adults.
- Trial name
- NCT05747742
- Testing
- RLRL device
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Diabetes Mellitus, Type 2, High-Intensity Interval Training
Effects of High Intensity Interval Training and Combined Training in Type 2 Diabetic (T2D) Patients
Diabetes has become a widespread epidemic, primarily because of the increasing prevalence and incidence of type 2 diabetes (T2D).
- Conditions
- Diabetes Mellitus, Type 2, High-Intensity Interval Training, Exercise Training, Hyperglycaemia Due to Type 2 Diabetes Mellitus
- Trial name
- NCT03593746
- Testing
- Physical training, Light-Emitting Diode (LED) therapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Breast Cancer
PBMT for the Prevention of CIPN
ne of the most common cancers in women worldwide is breast cancer. A common used therapy in early-stage and metastatic breast cancer involves chemotherapy.
- Trial name
- NCT03391271
- Testing
- photobiomodulation therapy (PBMT)
- Where
- Belgium
- Volunteers
- 53 people
- Sponsor
- Hasselt University
Oral Lichen Planus, Erosive Lichen Planus
Photobiomodulation, Photodynamic Therapy, and Clobetasol in the Treatment of Oral Lichen Planus.
This study aims to compare three treatment approaches for the erosive form of oral lichen planus, a chronic inflammatory condition that often causes pain, impaired oral function, and frequent relapses.
- Conditions
- Oral Lichen Planus, Erosive Lichen Planus, Mucosal Lesions
- Trial name
- NCT07278999
- Testing
- Photobiomodulation using 635 nm diode laser, Photodynamic therapy - laser mucosal treatment, Clobetasol propionate 0.05 percent topical application
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Striae; Albicantes
LLLT and Fractional CO2 Laser in the Treatment of Stria Alba
Stria alba (aka white or atrophic stretch marks) is a very common dermatologic condition that causes major psychological distress to those afflicted.
- Trial name
- NCT04165226
- Testing
- Low level light therapy, Fractional CO2, Combined fractional CO2 laser and low level light therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kasr El Aini Hospital
Rotator Cuff Tears, Rehabilitation
Effectiveness of Low-level Laser Therapy
During rotator cuff tear healing stages, there are complex interactions between a variety of tissue growth factors and cells, ultimately resulting in tissue that is markedly different from that of normal, uninjured tendon.
- Conditions
- Rotator Cuff Tears, Rehabilitation, Rotator Cuff Injuries
- Trial name
- NCT04836000
- Testing
- In addition to the conservative treatment, Low-level laser therapy, In addition to the conservative treatment, Low-level laser therapy (turned off), Conservative treatment solely
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Bronchiolitis, Virus
Effects of Photobiomodulation on the Innate Immune System of Neonates and Infants With Bronchiolitis
The innate immune response of children with acute viral bronchiolitis (AVB) caused by respiratory syncytial virus (RSV) in the acute phase and in the resolution phase, is marked by variations in inflammatory and anti-inflammatory…
- Conditions
- Bronchiolitis, Virus, Virus Disease
- Trial name
- NCT06396624
- Testing
- Intervention Group photobiomodulation, Control Group
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- Universidade Norte do Paraná
Postoperative Pain After Cesarean Section
Efficacy and Safety of Photobiomodulation for Postoperative Pain After Cesarean Section
Postoperative pain following cesarean section remains a major clinical challenge that can impair early maternal recovery, delay ambulation, and interfere with newborn care.
- Trial name
- BIOLUZCE (NCT07863960)
- Testing
- Photobiomodulation Therapy (MitoQUAD® Belt System)
- Where
- Honduras
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Vulvar Vestibulitis, Vestibulodynia
Cold Laser: A Modality to Promote Vulvar Healing and Pain Relief
The objectives of this pilot study are to demonstrate effectiveness of application of the Erchonia Laser (manufactured by Erchonia Corporation),a non-invasive, non-significant risk low level laser red diode light therapy device…
- Trial name
- NCT02204319
- Testing
- Cold laser
- Volunteers
- 10 people
- Sponsor
- ProHealth Care, Inc
Oral Mucositis, Osteoradionecrosis
Photobiomodulation in Oral Lesions Resulting From Anti-neoplastic Prevention
Introduction: There are several manifestations in the oral mucosa resulting from antineoplastic treatments by chemo (QT) or radiotherapy (RT).
- Conditions
- Oral Mucositis, Osteoradionecrosis, Osteonecroses, Bisphosphonate, Osteonecrosis Due to Drugs, Jaw
- Trial name
- NCT04717765
- Testing
- Preventive, LLL Phototherapy and topical Vit E, Curative, LLL Phototherapy and topical Vit E, Preventive, LLL Phototherapy and LPRF
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Santiago de Compostela
Dry Eye Syndromes, Meibomian Gland Dysfunction
Mechanisms of Light-based Therapies for Dry Eye Disease
Dry eye disease is a common condition affecting millions worldwide and costing millions in healthcare due to reduced work productivity and quality of life.
- Trial name
- MOLT (NCT06004895)
- Testing
- Actual IPL, LLLT
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Aston University
Wound, Diabetic Foot
Effect of the Use of Low Intensity Therapeutic LASER
Diabetes mellitus consists of a heterogeneous group of metabolic disorders that have hyperglycemia in common, resulting from defects in insulin action, insulin secretion, or both.
- Conditions
- Wound, Diabetic Foot, LTBI
- Trial name
- NCT05530486
- Testing
- CC, LG1, LG2
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of Piaui