Clinical trials: Lower Extremity Fracture
Hip Fracture
A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for…
- Trial name
- NCT01547468
- Testing
- Femoral Nerve Catheterization, Intravenous Opioids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leslie Thomas
Procedural Sedation
Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique
Abstract Background: Ketamine has been introduced as one of the most common drugs, administered to sedate children for different painful procedures in the emergency department (ED) but administration in higher dosage causes some…
- Trial name
- NCT03499886
- Testing
- Ketamine Hydrochloride 50Mg/1mL Solution for Injection, Ketamine Hcl 50Mg/Ml Inj
- Where
- 2 sites in Iran
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Hip Fractures
Patient-Centered Education After Hip Fracture Surgery
This randomized controlled trial aims to evaluate the effect of a structured patient-centered educational program on postoperative outcomes among patients undergoing hip fracture surgery.
- Trial name
- PCE-HFS (NCT07739225)
- Testing
- Structured Patient-Centered Educational Program.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Delirium (POD), Hip Fracture
Is the CRP-Albumin-Lymphocyte (CALLY) Index Effective in Predicting Postoperative Delirium in Geriatric Patients Undergoing Hip Fracture Surgery
Introduction: Postoperative delirium (POD) is a common complication in elderly surgical patients and is significantly associated with prolonged hospital stays, cognitive impairment, functional decline, and increased mortality…
- Conditions
- Postoperative Delirium (POD), Hip Fracture, CRP, Albumin
- Trial name
- NCT06818409
- Testing
- The Diagnostic and Statistical Manual of Mental Disorders (DSM) - 5 criteria for delirium diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Osteoporosis
Balance and Muscle Strength as Indicators of Fracture Risk in Postmenopausal Women
The study is designed as a cross-sectional clinical study. A total of 156 postmenopausal women who visited the Physical Therapy and Rehabilitation outpatient clinic at Beylikdüzü State Hospital and have had Dual X-ray…
- Trial name
- NCT06645600
- Testing
- Fracture risk
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Beylikduzu State Hospital
Fracture Pelvis
Comparison Between Dexamethasone and Dexmedetomidine in Spinal Anesthesia for Cases With Fracture Pelvis Fixation
The aim of this study is to compare dexamethasone and dexmedetomidine as adjuvant to bupivacaine in fracture pelvis fixation as regard duration of sensory block and postoperative pain management.
- Trial name
- NCT07485127
- Testing
- 60 patients will be involved, half patients will receive 13mg bupivacaine + 4 mg dexamethasone. The other half will receive 13mg bupivacaine + 4 mg dexmedetomidine. All will be monitored closely.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pertrochanteric Fracture, Intertrochanteric Fractures
Pertrochanteric Fracture Fixation In Elderly Adults Using Proximal Femoral Nail Anti-rotation (HERACLES) With a T-shaped Parallel Blade: A New Design
This is a prospective case series of elderly adult patients sustaining pertrochanteric fractures who will be treated by a proximal femoral nail with a non-helical (straight) blade.
- Conditions
- Pertrochanteric Fracture, Intertrochanteric Fractures, Pertrochanteric Fracture of Femur, Closed, Pertrochanteric Fracture of Femur, Open
- Trial name
- Heracles PFN (NCT03911180)
- Testing
- Proximal femoral nail with straight parallel blade
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ilocos Training and Regional Medical Center
Patella, Joint Instability
Development of a Test Battery for Measurement of Knee Function in Patients With Patellar Instability
About six months after patella stabilizing surgery postoperative restrictions are commonly lifted and patients may consider whether a return to activity/sports is feasible.
- Conditions
- Patella, Joint Instability, Patellofemoral Joint Dislocation
- Trial name
- NCT05119088
- Testing
- Return to Sport testbattery
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Haraldsplass Deaconess Hospital
Acetabular Fracture, Pelvic Fracture
Hip Strength and Nerve Palsy After the Modified Stoppa Approach to Acetabular Fracture Reduction and Fixation
The purpose of this prospective study is to compare hip adductor strength and obturator nerve palsy between acetabular fracture patients whose fracture was reduced and fixated using the modified Stoppa approach (subjects) and…
- Trial name
- NCT01763359
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Utah
Postoperative Pain, Femur Fracture
Comparing Suprainguinal Fascia Iliaca Block With Erector Spinae Plane Block in Hip and Proximal Femur Surgery
Most hip fractures occur in the elderly population. Opioid-related respiratory depression is more common in the elderly population but can cause severe brain damage or death.
- Conditions
- Postoperative Pain, Femur Fracture, Regional Anesthesia
- Trial name
- NCT05642975
- Testing
- Regional Block Comparison
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pelvic Fracture
Outcome of the Anterior Subcutaneous Internal Fixator (INFIX) for Pelvic Ring Disruptions
With a prospective case series study of 15 patients The aim of this study is to estimate the clinical outcomes in patients with unstable anterior pelvic ring fractures ( B\&C ) after treatment with (INFIX)
- Trial name
- NCT05354531
- Testing
- anterior subcutaneous internal fixator ( INFIX)
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hip Fractures
Dietary Patterns and Hip Fracture Risk in the UK Biobank
Hip fracture is a common serious injury in older adults that reduces mobility, independence, and quality of life, and can lead to premature death.
- Trial name
- NCT05554549
- Testing
- Dietary pattern observed
- Where
- United Kingdom
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Osteoporosis Risk, Fracture of Femur
Prediction Model of Hip Fragility Fracture Realistic Data From a Traumatology Department and Orthogeriatric Ward.
The aim of the project is to build a prediction model of hip fragility fracture using hospital data routinely collected in the traumatology department from the last 12 years and up to date Explainable Artificial Intelligence…
- Conditions
- Osteoporosis Risk, Fracture of Femur, Fragility
- Trial name
- NCT06545487
- Testing
- BLOOD SAMPLE
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Lower Extremity Fracture
Atropine Versus Glycopyrrolate in Preventing Spinal Anesthesia Induced Hypotension in Lower Limb Surgeries
A study to compare between intravenous atropine and glycopyrrolate in preventing spinal anesthesia induced hypotension in patients undergoing major lower limb orthopedic surgeries.
- Trial name
- NCT03580889
- Testing
- Atropine, Glycopyrrolate, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Nepal
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Proximal Femoral Fracture, Dinamic Hip Surgery
Motion Graphic Training for Scrub Nurses in Hip Surgery
This pilot randomized controlled trial evaluates the effect of motion graphic video-based training on the performance of scrub nurse students during dynamic hip screw (DHS) surgery.
- Trial name
- NCT07701564
- Testing
- Motion Graphic Video Training, Routine Clinical Training
- Where
- Iran
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arak University of Medical Sciences
Bony Weight Bearing Disorder
After Hip Fracture Nailing, Compare Early Weight Bearing as Tolerated (WBAT) Group With Weight Bearing Restriction(WBR)
Purpose: Proximal femur fracture is a major traumatic injury in elderly populations; however, practical postoperative weight-bearing protocols are lacking.
- Trial name
- NCT06329271
- Testing
- Early-Weight bearing
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Stroke, Acute, Parkinson Disease
Assessment of the Rehabilitative Effects of Curved-walking Training in Stroke, Parkinson and Orthopaedic Populations
The recovery of walking ability is crucial to promote independence in daily living and is one of the major goal of neuromotor rehabilitation.
- Conditions
- Stroke, Acute, Parkinson Disease, Femur Fracture
- Trial name
- NCT03545477
- Testing
- Novel locomotion treatment: curved-walking training, Standard locomotion treatment: straight-walking training, Standard physical therapy
- Where
- Italy
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Femur Fracture, Hip Fractures
Continuous Femoral Block With Levobupivacaine 0.125% or Ropivacaine 0.2% in Elderly Patients With Femoral Fractures
This study evaluates the continuous femoral block between levobupivacaine 0.125% and ropivacaine 0.2% in patients with proximal femoral fracture.These patients will be divided into 2 groups of 35 patients, one L group…
- Trial name
- NCT03815565
- Testing
- continuous femoral block
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hospital Municipal Miguel Couto