Clinical trials: Lower Extremity Fractures
Femoral Neck Fractures
Osseointegration of Hydroxyapatite-coated Femoral Stems in Femoral Neck Fractures Over 80 Years
This study aimes to prove that osseointegration of hydroxyapatite coated stem is possible for patients over 80 years with femoral neck fracture, without the risks of cemented stems.
- Trial name
- NCT04773145
- Testing
- Hemiarthroplasty with hydroaxyapatite coated stem
- Where
- France
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Femoral Neck Fractures, Pertrochanteric Fracture
Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures
The aim of this clinical trial is to compare serum concentration of bone intake proteins [ sex hormone-binding globulin (SHBG), cross linked C-telopeptide of type I collagen (CTX-I)] and muscle atrophy marker [creatine kinase…
- Conditions
- Femoral Neck Fractures, Pertrochanteric Fracture, Bone Resorption, Bone Loss
- Trial name
- NCT05804604
- Testing
- Surgical treatment of proximal femur fracture and blood sample test, Blood sample test
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Hip Fractures, Cognitive Impairment
Hip Fracture Exercise and Rehabilitation Post Hip Fracture Study
This pilot study will look at whether it is possible to give better physical therapy to people with cognitive limitations who have had a hip fracture.
- Trial name
- HipERS (NCT03247205)
- Testing
- HipERS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Syndesmotic Injuries
Syndesmotic Screw in Neutral Position Versus Maximum Ankle Dorsiflexion in Ankle Fractures; Comparative Study.
Ankle fracture is one of the most common orthopedic injuries. Approximately, 20% of surgically treated ankle fractures are associated with syndesmotic instability.According to the mechanism of the injury the syndesmotic…
- Trial name
- NCT06313177
- Testing
- syndesmosis fixation with screws
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Ankle Fracture - Medial Malleolus
Medial Malleolus: Operative Or Non-operative
Medial malleolus: Operative Or Non-operative (MOON study) Ankle fractures are a common Orthopaedic trauma presentation, accounting for approximately 10% of the workload.
- Trial name
- MOON (NCT03362229)
- Testing
- Fixation, Non-fixation
- Where
- United Kingdom
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Royal Infirmary of Edinburgh
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Hip Fractures
Anterior vs Posterior Approach for Hip Hemiarthroplasty
Randomized trial to evaluate the role of the anterior vs posterior approach regarding hemiarthroplasty of the hip. The Investigators' hypothesis is that the muscle sparing anterior approach may result in improved function in the…
- Trial name
- NCT04957251
- Testing
- anterior approach to the hip, posterior approach to the hip
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mount Carmel Health System
Osteoporosis, Diet Habit
Soft Drinks and Osteoporosis in WHI Participants
Osteoporotic fractures, as a consequence of a reduced mineral bone density (BMD) represents a major public health problem. The lifetime risk of fractures exceeds 40% for women and 13% for men.
- Trial name
- NCT03371433
- Testing
- Soft drinks
- Volunteers
- 79,885 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery
The Effects of General Versus Spinal Anesthesia on Postoperative Myocardial Injury
In this prospective, randomized, single-blind study, we aim to compare the effects of general anesthesia and spinal anesthesia on postoperative myocardial injury in elderly patients undergoing hip surgery.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Hypotension During Surgery, Anesthesia, General, Anesthesia, Spinal
- Trial name
- NCT06343259
- Testing
- General Anesthesia, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hip Fractures
Tele-rehabilitation Intervention for People Post Hip Fracture - Randomized Controlled Trial (RCT)
Most surviving hip-fracture patients experience reduced mobility and lose their functional ability, which increases the risk of complications and rehospitalization.
- Trial name
- NCT03376750
- Testing
- CO - OP
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Herzog Hospital
Physical Therapy Modalities, Pain Measurement
How to Reduce Dry Needling Pain in Treatment of Trigger Points of Muscle Triceps Sural in Ankle Post Fracture Patients
Ankle fractures are one of the main causes of hospitalization due to injuries in Chile, which also have a discharge and partial load time of approximately 12 weeks in the recovery process.
- Conditions
- Physical Therapy Modalities, Pain Measurement, Trigger Point Pain, Myofascial, Ankle Fractures
- Trial name
- NCT05193695
- Testing
- Treadmill exercise
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Becerra, Pablo
Fractures
Evaluation of the Change in Length of the Leg in Children After Treatment of Femur Fractures.
Femur fractures are a common injury in the Pediatric population. Despite their high incidence little do we know about the long term implications on the bones' length.
- Trial name
- NCT00355420
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Arthroscopic Knee Surgery, Lower Limb Fractures
Comparison of Gait Parameters Between Floor and Sponge Surfaces and Special Shoes
This study compares the gait pattern of individuals with weight bearing difficulties walking on the floor, a soft surface, or with special shoes (Kyboot).
- Conditions
- Arthroscopic Knee Surgery, Lower Limb Fractures, Back Pain and Asymmetric Gait, Complex Regional Pain Syndrome
- Trial name
- NCT02742376
- Testing
- Soft surface, Floor, Kyboot shoes
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Femur Fracture
Pediatric Femur Research Project
Current treatment protocol for pediatric femoral shaft fractures is immediate spica casting for patients 6 years and younger and for patients over 6 years and older is percutaneous or open placement of titanium elastic…
- Trial name
- NCT00943332
- Testing
- femur fracture repair
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hip Injuries, Hip Fractures
Is the Rate of Early Mobilisation in Hip Fracture Patients Using Alfentanil Better Than Standard Opioid Analgesia?
Hip fracture injuries are linked with increased morbidity, frailty, and mortality risk. Studies have shown that in hip fracture surgery, early mobilisation confers better pain control, 30-day complication and mortality rates and…
- Conditions
- Hip Injuries, Hip Fractures, Pain, Post Operative Pain
- Trial name
- REHAB (NCT06212622)
- Testing
- Alfentanil, Oxycodone
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- NHS Lothian
Hip Fractures
Blood Loss After Early TXA in Hip Fractures.
Our present study aims to initiate TXA administration immediately upon diagnosis of hip fracture in the Emergency Department. This will be a single blind randomized controlled trial comparing early administration of TXA in the ED…
- Trial name
- NCT04488367
- Testing
- Tranexamic acid, Normal Saline
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Community Memorial Health System
Accidental Fall, Fall
Remote Monitoring and Analysis of Gait and Falls Within an Elderly Population
The investigators aim to do this initial pilot study as an observational prospective cohort study, evaluating elderly patients who have capacity in National Health Service (NHS) rehabilitation and community hospitals.
- Conditions
- Accidental Fall, Fall, Fall Injury, Hip Fractures
- Trial name
- 4279 (NCT03680014)
- Testing
- CUSH
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CUSH Health Ltd.
Hip Fracture
A Comparison of Two Pain Control Techniques on Deliruim in Hip Fracture Patients
The purpose of this study is compare the rates of post-operative delirium between a group of people receiving intravenous (IV) pain control after hip fracture surgery and a group of people receiving a femoral nerve catheter for…
- Trial name
- NCT01547468
- Testing
- Femoral Nerve Catheterization, Intravenous Opioids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Leslie Thomas
Procedural Sedation
Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique
Abstract Background: Ketamine has been introduced as one of the most common drugs, administered to sedate children for different painful procedures in the emergency department (ED) but administration in higher dosage causes some…
- Trial name
- NCT03499886
- Testing
- Ketamine Hydrochloride 50Mg/1mL Solution for Injection, Ketamine Hcl 50Mg/Ml Inj
- Where
- 2 sites in Iran
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anesthesia, Hip Fractures
Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)
The ANDES Platform Trial is a pragmatic, multicenter, adaptive randomized controlled platform trial in patients aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Anesthesia, Hip Fractures, Dementia, Cognitive Impairment
- Trial name
- ANDES platform (NCT06452147)
- Testing
- Nerve block, Standard anesthesia care, Bupivacaine liposome
- Where
- 13 sites in China
- Volunteers
- 1,860 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University