Clinical trials: Lower Extremity Function
Iliotibial Band Syndrome, Pain
Effects of Functional Motor Control on Pain, Flexibility, Lower Extremity Function With ITBS
The study is randomized and single-blinded. Ethical approval is taken from ethical committee of Riphah International University, Lahore.
- Conditions
- Iliotibial Band Syndrome, Pain, Flexibility
- Trial name
- NCT06131658
- Testing
- Functional motor control excercise, convectional excercise
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ankle Fracture, Trimalleolar, Ankle Fracture - Lateral Malleolus
Operative Treatment of Ankle Fractures
Patients who underwent operative treatment of an ankle fracture with or without following removal of the osteosynthetic material are examined by a specific ankle provocation test, a questionnaire and X-Rays to evaluate the…
- Conditions
- Ankle Fracture, Trimalleolar, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar
- Trial name
- NCT04437355
- Testing
- Specific provocation test
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Spital Limmattal Schlieren
Neuromuscular Function, Postural Balance
"Muscle Strength, Balance, and Core Endurance in Elite Adolescent Rowers: A Cross-Sectional Study"
This study aims to investigate the relationship between lower extremity isokinetic strength, dynamic balance, and core muscle endurance in elite adolescent rowers aged 16-18.
- Conditions
- Neuromuscular Function, Postural Balance, Core Stability, Muscle Strength
- Trial name
- REBCORE (NCT07077993)
- Where
- Cyprus
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Traumatic Amputation of Lower Extremity
A Comparison of External Mechanical Work Between Different Prosthetic Feet
Recent dysvascular and diabetic amputees as well as older, long-term traumatic amputees are at risk of functional decline, joint degeneration, skin breakdown and further limb loss due to the forces placed on the contralateral…
- Trial name
- SEW (NCT01340807)
- Testing
- Specialized Functional Prosthetic Training
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Miami VA Healthcare System
Anterior Cruciate Ligament Tear
Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique
The purpose of the study is a clinical evaluation with special regard to magnetic resonance imaging and functional performance at least one year after injury / surgery in all three groups (subjects who underwent InternalBrace…
- Trial name
- NCT02760589
- Where
- Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- AUVA
Myocardial Injury
Sufentanil in Patients With Lower Extremity Fracture Surgery Myocardial Damage Function Study
1. To analyze the association of different doses of opioids on myocardial injury/protection through BMP-6/SMAD pathway. 2. To observe the effect of different doses of opioids on the expression of BMP-6 in bone marrow. 3.
- Trial name
- Sipwlefsmdfs (NCT06808841)
- Testing
- Sufentanil injection
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Running, Leg Injuries
Exercise Interventions, Running Biomechanics and Injury in Novice Runners
The purpose of this study is to understand the effects of muscle strengthening and balance exercise interventions on muscle strength, running mechanics and postural control in novice recreational runners.
- Trial name
- NCT01900262
- Testing
- Strengthening, Balance Training, Stretching
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pregnancy Related
Effects of Foot Exercises and Hydrotherapy on Pedal Edema & Lower Extremity Function
To determine the Effects of foot exercises with and without hydrotherapy on pedal Edema \& lower extremity function in antenatal women.
- Trial name
- NCT05777538
- Testing
- hydrotherapy, foot exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Injuries
Influence of Proprioceptive Reweighting Ability on Lower-limb Biomechanics During Functional Tasks
Anterior cruciate ligament (ACL) injuries are frequent in handball especially among young players. Recent investigations highlighted the implication of the central nervous system as a potential risk factor for ACL rupture.
- Trial name
- NEURIBIO (NCT04736511)
- Testing
- Star Excursion Balance Test, Single leg Drop Vertical Jump, Unplanned sidestep cutting manoeuvre
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Spinal Cord Injuries, Stroke
Restorative Neuromodulation for Lower Extremity Functions
The overall objective of the proposed study is to restore lower-extremity functions of paraplegic individuals. Paralysis following Stroke or spinal cord injury (SCI) result harsh sufferings including lifelong dependence on…
- Conditions
- Spinal Cord Injuries, Stroke, Paralysis
- Trial name
- NCT04171375
- Testing
- trans-spinal Electrical Stimulation (tsES)
- Where
- Hong Kong
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Healthy Subject
Francis Biomechanics Study
This study aims to evaluate the effect of a range of pre-formed orthoses on function of the foot and leg to generate technical data on how the individual insoles impact gait, distribution of load and stability in a healthy…
- Trial name
- NCT03662399
- Testing
- Insoles, Standard shoe
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Total Knee Arthroplasty
Comparison Between Brainlab Knee 3 Computer-assisted Navigation Systems and Conventional Instruments in TKA: a Prospective Cohort Study.
This is a a prospective cohort study. According to the inclusion criteria, volunteers were recruited from patients undergoing total knee arthroplasty.
- Trial name
- NCT04960345
- Testing
- Brainlab Knee 3
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Football Players
Efficacy of Plyometric Training Isometric Strength Training on Quadriceps Strength and Functional Performance.
This study aims to investigate the influence of an eight-week plyometric and quadriceps strength training program on muscular strength, sprint, and functional performance in collegiate football players.
- Trial name
- Isometric (NCT05056792)
- Testing
- Isometric strength training for 8 week, Conventional training
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Majmaah University
Accidental Falls
Lower-limb Strength and Flexibility Program on Prevention of Falls in the Community-dwelling Elderly
Accidental falls result in major physical and psychological morbidity in the elderly. The aim of this study was to evaluate the effects of lower-limb strength and flexibility program, which is analyzed under the control of other…
- Trial name
- NCT01830634
- Testing
- Theraband with strengthening and stretching exercise
- Where
- Taiwan
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Multidomain Intervention
Effects of Passive Lower-limb Exoskeleton-assisted Training on Motor and Daily Function Improvements in Older Adults
According to National Development Council estimation, Taiwan is about to enter a super-aged society in 2025, and health promotion for the elderly are critical issues nowadays.
- Trial name
- NCT06543888
- Testing
- passive exoskeleton- assisted gait training programs, Conventional gait training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Chronic Ankle Instability, Ankle Sprain
Impact of Chronic Ankle Instability on Jumping and Agility in Athletes
This study investigated how chronic ankle instability (CAI) affects functional performance in athletes compared with healthy controls.
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Functional Performance Deficit, Athletic Performance
- Trial name
- NCT07171398
- Testing
- Functional Performance Testing Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Healthy
Combining Resting Blood Flow Restriction with Neuromuscular Electrical Stimulation: Effects on Blood Lactate Levels and Lower Limb Muscle Function
The current research landscape shows studies indicating increased muscle strength and hypertrophy through neuromuscular electrical stimulation combined with blood flow restriction.
- Trial name
- NCT06196099
- Testing
- Blood Flow Restriction, Neuromuscular Electrical Stimulation, Squat exercise
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hyunjoong Kim
Spinal Cord Injuries
Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323698
- Testing
- Caffeine, AIH
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Primary Lymphedema
Primary Lymphedema and Mutation CELSR1 (Cadherin EGF LAG Seven-pass G-type Receptor 1)
The investigators will describe the expression of mutation CELSR1 with codon stop and amino acids substitution mechanism in primary lymphedema, in both clinical examination and imaging exploration
- Trial name
- CELSR1 (NCT04919655)
- Where
- France
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Knee Arthritis, Osteoarthritis, Osteo Arthritis of the Knee
Quadriceps Muscle Quality and Clinical Outcomes in Knee Osteoarthritis
The purpose of this cross-sectional, observational study is to evaluate the relationship between quadriceps muscle quality-specifically muscle echogenicity and thickness change during isometric contraction-and clinical outcomes…
- Trial name
- NCT07541274
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir City Hospital