Clinical trials: Lower Extremity Function
Ankle Fractures
Ankle Fracture vs Ankle Fracture-Dislocation
The purpose of this study is to compare outcomes of patients with an ankle fracture to those with ankle fracture-dislocations. We hypothesize that long-term clinical outcomes for patients sustaining ankle fracture dislocations…
- Trial name
- NCT02198768
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Hip Fractures (ICD-10 72.01-72.2)
Improving Shared DECISion-making in oldEr Hip Fracture Patients Living With Frailty
Title Improving shared decision-making in older hip fracture patients living with frailty Aim To use routinely information normally collected by the NHS, and interviews with patients, families, and healthcare professionals, to…
- Conditions
- Hip Fractures (i.e. Femoral Neck or Intertrochanteric Hip Fractures), Hip Fractures (ICD-10 72.01-72.2), Hip Fracture, Hip Fracture, Post Surgery Recovery, Muscle Resilience
- Trial name
- DECIDE-HIP (NCT07687108)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Southampton
Pes Planus, Pronated Foot
Effect of Trunk Stabilization on Pronated Feet
the purpose of this study is to investigate The effect Trunk stabilization on dynamic balance and foot function of pronated foot posture.
- Trial name
- NCT07734168
- Testing
- trunk stabilization exercise, pronated foot posture exercise
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Flatfoot, Flexible, Pes Valgus
Physiotherapy Program Effect on Musculoskeletal Dysfunctions in Young Football Players
The goal of this clinical study is to test the proposed physiotherapy exercise program in young football players. The main question it aims to answer is: Does the proposed physiotherapy program work well in improving young…
- Conditions
- Flatfoot, Flexible, Pes Valgus, Pes Varus, Balance; Distorted
- Trial name
- NCT05798988
- Testing
- Neurophysiology-based exercise program
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Stroke
A Study on the Effectiveness Evaluation in Stroke Patients Using Lower Limb Assistive Walking Devices
The main purpose of this clinical trial is to evaluate the effectiveness and safety of the MI-R1 walking machine in lower limb motor function training for stroke patients. The main question is to answer: 1.
- Trial name
- NCT06564480
- Testing
- MI-R1 lower limb walking machine assisted training device, Walking rehabilitation training under the guidance of therapists
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Peripheral Arterial Disease, Critical Limb Ischemia
BOLD MRI as a Surrogate of Improved Muscle Oxygenation Following Endovascular Therapy for the Treatment of CLI
The purpose of this study is to determine if an MRI technique called Blood Oxygen Level Dependent, or BOLD, can be used to evaluate blood flow in the leg before and after treatment with standard endovascular therapy in patients…
- Trial name
- NCT02601430
- Testing
- BOLD-MRI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Zimmer Biomet
Anterior Cruciate Ligament Injury
Neuromuscular Profiles After Anterior Cruciate Ligament Reconstruction
The NEURO-ACL-ISOEMG study is an observational, cross-sectional, exploratory study conducted in patients between 4 and 12 months after anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NEURO-ACL-ISOE (NCT07792863)
- Testing
- Neuromuscular and Patient-Reported Assessmen
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hopitaux de Saint-Maurice
Sedentary Behavior, Peripheral Circulation
Buerger-Allen Exercises and Peripheral Circulation in Sedentary Office Workers
This study aims to evaluate the acute effects of Buerger-Allen exercises on lower extremity circulation in sedentary office workers.
- Conditions
- Sedentary Behavior, Peripheral Circulation, Vascular Function
- Trial name
- BAE-CIRC (NCT07588893)
- Testing
- Buerger-Allen Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Subacute Stroke, Ischemic Stroke
Segmental Vibrator With NMES on Lower Limb Function in Subacute Stroke
Stroke is one of the world's leading causes of death and disability. It can cause a variety of motor disorders, such as apraxia, sensory deficits, abnormal muscle tone, inadequate weight transfer, lack of fine motor skills…
- Trial name
- NCT06927206
- Testing
- Experimental Group A: Segmental vibrator only on dorsiflexor, Experimental Group B: Segmental vibrator + Electrical stimulation on dorsiflexors
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Stroke
Comparative Effects of Backward Treadmill Walking and Lower Extremity Cross Training Among Stroke Patients
Stroke is one of the high rated neurological disorders, induced by disruption of brain's blood flow. Stroke can alter the level of consciousness, motor and cognitive skills, sensory perception and language; it all depends on the…
- Trial name
- NCT05834192
- Testing
- Backward treadmill walking, Lower extremity cross training
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Lower Limb Amputation Above Knee (Injury)
C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
The aim of this post-market study is to confirm that the microprocessor controlled prosthetic knee components (C-Leg 3 and C-Leg 4) in comparison to mechanical knee joints can bring additional benefit to the users primarily on…
- Trial name
- NCT02765035
- Testing
- C-Leg 4, C-Leg 3
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 18 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
Study to Evaluate the Safety and Effectiveness of REAL INTELLIGENCE™ CORI™ in Unicondylar Knee Arthroplasty (UKA) Procedures
This is a prospective study to demonstrate the safety and effectiveness of CORI and to register CORI in China mainland.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Requires Correction of Functional Deformity
- Trial name
- CORI RCT UKA (NCT04797897)
- Testing
- CORI, Conventional
- Where
- 3 sites in Australia, Hong Kong and 1 more
- Volunteers
- 4 people
- Sponsor
- Smith & Nephew, Inc.
Healthy
Effects of Heavy-load Resistance Training
The study aims to investigate effects of 8-weeks of heavy-load resistance training on mechanical muscle function and functional performance in elite female team handball players from the Danish Women's Handball League.
- Trial name
- NCT06356935
- Testing
- RT, CON
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Stroke, Post-Stroke Spasticity
Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients
This study aims to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in individuals with lower limb spasticity following stroke.
- Conditions
- Stroke, Post-Stroke Spasticity, Lower Limb Spasticity
- Trial name
- ESWT-STROKE (NCT07523243)
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Istanbul Medipol University Hospital
Pilon Fracture of Tibia
Pilon Fracture Reduction and Functional Outcome
This prospective case series will essentially examine the influence of reduction quality on the primary functional outcome (as assessed using the FAAM) of patients with pilon fractures treated with plate fixation.
- Trial name
- NCT01316289
- Where
- 9 sites in United States, Austria and 2 more
- Volunteers
- 117 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Injuries, Musculoskeletal Pain
Translation and Psychometric Validation of an Italian Version of the Dance Functional Outcome Survey DFOS-IT
Study Design: Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. Objective: Translating, culturally adapting, and validating the Italian version of the Dance Functional Outcome Survey…
- Conditions
- Injuries, Musculoskeletal Pain, Low Back Pain, Lower Limb Injury
- Trial name
- DFOS-IT (NCT03918876)
- Where
- Italy
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Angela Contri
Spinal Cord Injuries
Intermittent Theta Burst Stimulation and Repetitive Transcranial Magnetic Stimulation Combined With Robotic Rehabilitation on Ambulation in Spinal Cord Injury Patients
Comparison of different types of transcranial magnetic stimulation techniques which are intermittent theta burst stimulation (iTBS) and high frequency repetitive transcranial magnetic stimulation (rTMS) in patients with spinal…
- Trial name
- NCT06248476
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Post Stroke, Lower Limb
Comparative Effects of SBES Versus TOT on Lower Limb Motor Function in Post-Stroke Patients
Stroke-induced lower limb impairments severely inhibit functional independence and mobility in survivors. Inventive techniques like Synergy-Based Electrical Stimulation (SBES) and Task-Oriented Training (TOT) support favorable…
- Trial name
- NCT07718776
- Testing
- synergy Based Electrical stimulation, Task oriented training
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Aging, Walking
Effects of a Powered Lower-Limb Exoskeleton on Walking Performance in Older Adults
The goal of this clinical trial is to learn whether a powered wearable lower-limb exoskeleton can improve walking performance in independently ambulatory older adults aged 65 to 75 years.
- Conditions
- Aging, Walking, Physical Function, Mobility Limitation
- Trial name
- E-WALK (NCT07633093)
- Testing
- Powered Lower-Limb Exoskeleton
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hunan Normal University
ACL Reconstruction, ACL Injury
Validity of the SHD-LESS Scale After ACL Reconstruction
After anterior cruciate ligament reconstruction (ACL-R), Single Hop for Distance (SHD) performance aids in decision-making, particularly for return-to-sport assessments.
- Trial name
- ACL-LESS (NCT06829849)
- Testing
- Landing error assessment during a SHD task using the SHD-LESS scale
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen