Clinical trials: Lower Extremity Muscle Strength, active
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
Vitamin D to Improve Quadricep Muscle Strength
Quadriceps muscle strength is one of the key determinants for patients to fulfill the Return-to-Play (RTP) criteria after an anterior cruciate ligament reconstruction (ACLR), in which the muscle size is directly linked to muscle…
- Conditions
- Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05174611
- Testing
- Vitamin D3
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Cognitive Functioning of Healthy Individuals, Balance
Task-Specific Training vs. Yoga (With and Without Perturbation) for Balance and Leg Strength in Older Adults
This experimental study is designed to observe the effectiveness of task-specific training vs yoga with and without perturbation on reactive balance and leg strength in older individuals in Islamabad/Rawalpindi, Pakistan.
- Conditions
- Cognitive Functioning of Healthy Individuals, Balance, Strength, Muscle, Quality of Life (QOL)
- Trial name
- NCT06875388
- Testing
- Task specific Training, Specific Yoga Poses, Tasl specific Training with perturbation
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Lipedema
Effects of Exercise in Patients with Lipedema
Lipedema is a chronic progressive disease characterized by symmetrical, disproportionate swelling of subcutaneous adipose tissue, which is common in women and mostly seen in the lower extremities and to a lesser extent in the…
- Trial name
- NCT06811961
- Testing
- Exercise, Physical activity
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ilke Keser
Menstrual Cycle, Physical Performance
Menstrual Cycle and Women's Performance
This study examines how different phases of the menstrual cycle are associated with selected performance and musculoskeletal parameters in physically active women aged 18-35 years.
- Conditions
- Menstrual Cycle, Physical Performance, Muscle Strength, Musculoskeletal System
- Trial name
- NCT07462286
- Testing
- Menstrual Cycle Tracking, Performance and Strength Testing, Musculoskeletal Assessment
- Where
- Czechia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Stroke
Effects of Peripheral Somatosensory Stimulation Through Mechanical Pressure on Lower Limb Muscle Strength in Stroke Survivors
Somatosensory information is essential for the motor system because when the central nervous system stops receiving afferent signals, it cannot use information about the state of the affected body part to plan or adjust movement.
- Trial name
- NCT06958185
- Testing
- deep peripheral sensory stimulation
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Pedro Victor López Plaza
Tibial Fracture
Blood Flow Restriction Therapy to Optimize Muscle Size and Strength in Recovery From Lower Limb Fractures
This study will assess the feasibility and effectiveness of blood flow restriction therapy in patients with tibia fractures (or lower leg bone).
- Trial name
- BOOST (NCT07103252)
- Testing
- Blood Flow Restriction Therapy
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Anterior Cruciate Ligament Injuries, Knee Injuries
Effects of Early Rehabilitation Using Blood Flow Restriction and/or Surface Electromyography Biofeedback on Quadriceps Activation and Strength After Anterior Cruciate Ligament Reconstruction: A Multicenter Randomized Controlled Trial
Many patients experience quadriceps inhibition after anterior cruciate ligament (ACL) reconstruction, delaying strength recovery, hindering return to sport, and potentially increasing the risk of re-injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Knee Injuries, Muscle Weakness
- Trial name
- NCT07145606
- Testing
- Standard Rehabilitation, Blood Flow Restriction (BFR) Training, sEMG Biofeedback
- Where
- 4 sites in France, Switzerland
- Volunteers
- 200 people
- Sponsor
- Haute Ecole ARC Sante
Physical Performance, Leg Muscle Mass
Lower-Limb Muscle Mass and Cardiovascular and Muscular Performance in Males and Females
The aim of this study will be to examine the relationship between leg muscle mass and muscle strength, aerobic capacity, anaerobic power, and jumping performance in young adults.
- Conditions
- Physical Performance, Leg Muscle Mass, Muscle Strength, Aerobic Capacity
- Trial name
- NCT07440615
- Testing
- Physical Performance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Uludag University
Pes Planus, Flatfoot
Peripheral Magnetic Stimulation of Foot Muscles: Effects on Medial Longitudinal Arch Height and Foot Muscle Strength in Adults With Flat Feet
This study examines the effects of repetitive peripheral magnetic stimulation (rPMS) on foot invertor muscle strength, morphology, and the height of the medial longitudinal arch (MLA) in individuals with flat feet.
- Conditions
- Pes Planus, Flatfoot, Posterior Tibial Tendon Dysfunction
- Trial name
- rPMS-Foot (NCT07237321)
- Testing
- Repetitive Peripheral Magnetic Stimulation (rPMS)
- Where
- 2 sites in Slovenia
- Volunteers
- 30 people
- Sponsor
- University of Ljubljana
Anterior Cruciate Ligament Reconstruction Rehabilitation, Blood Flow Restriction (BFR) Training Effects
Effect of Blood Flow Restriction Rraining on Rehabilitation After Anterior Cruciate Ligament Reconstruction
Importance: Following anterior cruciate ligament reconstruction (ACLR), patients often experience quadriceps muscle weakness and atrophy, frequently leading to long-term complications.
- Trial name
- NCT07311031
- Testing
- Blood flow restriction training, Standard ACL rehabilitation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital MAZ
Anterior Cruciate Ligament Rupture
BFRT in Adolescents After ACL Reconstruction
This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR).
- Trial name
- NCT04390035
- Testing
- Blood Flow Restriction using Delfi Personalized Tourniquet System
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Transfemoral Amputation
Assessment of Strength, Balance, and Function in Above-Knee Amputees in Relation to Residual Limb Length
The goal of this observational study is to learn how muscle strength, balance, and functional ability are affected in people with above-knee (transfemoral) amputations.
- Trial name
- NCT07032233
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ceren Kuzu
Workplace Health Promotion, Muscle Strength
Effects of Jive Dance Training on Lower Limb Muscle Strength
The purpose of this study is to evaluate the effects of a structured, partner-free Jive dance training program on the physical and cognitive health of hospital employees.
- Conditions
- Workplace Health Promotion, Muscle Strength, Postural Balance
- Trial name
- NCT07641465
- Testing
- Systematic Solo Jive Dance Training
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- E-DA Hospital
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Pediatric-Onset Multiple Sclerosis (POMS)
Five Times Sit-To-Stand Test for Patients with Pediatric-Onset Multiple Sclerosis
Transitioning from a sitting to a standing position is a movement essential for maintaining physical independence and functional mobility, and is necessary for performing many activities in daily life.
- Trial name
- NCT06648499
- Testing
- Evaluation of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue in POMS, Evaluation of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue in healthy controls
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Balance, Lower Extremity
Foot Biomechanics and Lower Extremity Muscle Mechanics
This study is designed to investigate the relationship between foot biomechanics, balance, lower extremity muscle mechanical properties, and vertical jump in young adults.
- Conditions
- Balance, Lower Extremity, Foot
- Trial name
- NCT06849531
- Testing
- Foot Biomechanics and Lower Extremity Muscle Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Lower Extremity Muscle Strength
Pro-social Power Training Activity for Aging and Well-being With Chronic Kidney Disease
This is a pilot trial of a 16-week physical activity and power training program among up to 30 Veterans/arm with advanced chronic kidney disease. The trial aims to test whether the program is tolerable to Veterans.
- Trial name
- NCT06089057
- Testing
- Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease, Attention Control for Pro-social Power training Activity for Aging and Well-being with Chronic Kidney Disease
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Mechanical Ventilation, Critical Illness
Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)
This clinical study aims to compare the effects of conventional physical therapy alone versus conventional physical therapy combined with neuromuscular electrical stimulation (NMES) in patients admitted to the ICU and undergoing…
- Conditions
- Mechanical Ventilation, Critical Illness, Intensive Care Unit Patients, Muscle Weakness Condition
- Trial name
- MOVCARE (NCT07188350)
- Testing
- Conventional Physical Therapy, Neuromuscular Electrical Stimulation (NMES)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital Moinhos de Vento
Healthy Volunteers
Effects of Peripheral Somatosensory Stimulation Via Mechanical Pressure on Lower Limb Muscle Strength in Healthy Subjects.
The proprioceptive system and strength are closely related within the sensorimotor system: proprioception enables effective and coordinated muscle activation (including intramuscular and intermuscular coordination or synergistic…
- Trial name
- NCT06936020
- Testing
- deep peripheral sensory stimulation
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Facultat de ciencies de la Salut Universitat Ramon Llull
Ankle Sprains
Comparison of the Effects of Hip and Ankle Focused Progressive Exercise Training on Lower Extremity Function in Athletes With Chronic Ankle Instability
Chronic ankle instability refers to a combination of persistent mechanical and functional instability symptoms following an ankle sprain.
- Trial name
- NCT07319403
- Testing
- Gluteus Medius, Gluteus Maximus, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University