Clinical trials: Lower Extremity Wound
Athletic Injuries, Knee Injuries
Analysis of Balance and Functional Hop Tests in Athletes With Lower Extremity Injuries by Dual Task Study
Functional Hop tests and balance measurements are frequently used to decide on returning to sports after lower extremity injuries.
- Conditions
- Athletic Injuries, Knee Injuries, Ankle Injuries, Hip Injuries
- Trial name
- NCT05484778
- Testing
- Dual tasking paradigm
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Diabetic Foot Ulcer Healing Trajectories
Efficacy of Negative Pressure Wound Therapy Versus Conventional Moist Dressings on Diabetic Foot Ulcer Healing Trajectories
Background: Diabetic foot ulcers (DFUs) are severe, chronic complications of diabetes carrying a high risk of amputation. While Negative Pressure Wound Therapy (NPWT) is an active biophysical treatment, clinical evidence using…
- Trial name
- DF-WOUND-RCT (NCT07745075)
- Testing
- Vacuum-Assisted Closure (VAC / NPWT)
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jerash Private University
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Amputation Wound, Traumatic Amputation of Toe
Longitudinal Study of Weight Change Following Lower Limb Amputation
The purpose of this study is to assess weight change in a population of Veterans with amputations. Little is known about the how weight changes following an amputation.
- Conditions
- Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
- Trial name
- NCT00932399
- Where
- United States
- Volunteers
- 4,549 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabetic Foot, Wound Heal
The Effect of Combined 650 nm and Infrared Laser on Chronic Diabetic Foot Ulcer Surface Area:
Objective: investigate the effect of combined 650 nm and infrared laser on chronic diabetic foot ulcer surface area. Participants: The forty five patients will assigned randomly into three equal groups, each group consist of 15…
- Trial name
- wounds (NCT05517863)
- Testing
- laser therapy
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Heidy F. Ahmed
Knee Hyperextension
Lower Extremity Alignment and Dynamic Control With Associated Injury Risk in College Athletes With Knee Hyperextension
Knee hyperextension, also called genu recurvatum or back knee, is commonly seen in women, people with ligamentous laxity, stroke and cerebral palsy patients.
- Trial name
- NCT03425968
- Where
- Taiwan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Basketball
A Gluteus Maximus Strength Exercise Effectiveness for Improving Dynamic Postural Control in Female Basketball Players
The study will be carried out at the Faculty of Nursing and Physiotherapy of the University of Alcalá. The study has been approved by the Animal Research and Experimentation Ethics Committee of the University of Alcalá.
- Trial name
- NCT05206786
- Testing
- Conventional preventive work out, Gluteus maximus strengthening specific program
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Lower Limb Amputation Below Knee (Injury)
Comprehensive Evaluation of the Passive Talaris Demonstrator
The passive Talaris Demonstrator (TD) is developed in continuation of previous prototypes. The main goal of the experiment is to evaluate the effectiveness of TD during daily activities.
- Trial name
- NCT05127993
- Testing
- Passive Talaris Demonstrator
- Where
- Belgium
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Venous Ulcer, Low-Level Light Therapy
Low-level Light Therapy on Treatment of Venous Ulcers Assesed by Nursing Outcome Classification (NOC)
This study compares the effect of adjuvant treatment of Low-level Light Therapy with conventional treatment in the tissue repair of venous ulcers in patients undergoing outpatient nursing consultation.
- Trial name
- LASERUVe (NCT03229330)
- Testing
- Low-level Light Therapy, Conventional treatment
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Wound Healing
Efficacy of Early Postoperative ON101 Application for Lower-extremity Fracture Incisions: a Prospective Evaluator-blinded Controlled Study of Scar Quality and Digital-clinical Concordance
Background: Postoperative scars after lower-extremity fracture fixation endure high tension, where excessive scarring can restrict periarticular mobility.
- Trial name
- ON101 Efficacy (NCT07854470)
- Testing
- ON101
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LIN Kai-Cheng
Hemorrhage, Hypovolemic Shock
Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs
The goal of this clinical trial is to compare the occlusive capability and mechanical behavior of different commercially available pre-hospital tourniquet models and the results of their application on upper and lower limbs, in…
- Conditions
- Hemorrhage, Hypovolemic Shock, Tourniquets
- Trial name
- TQ-BR (NCT06725602)
- Testing
- TQ - Proximal Application ("high and tight"), TQ - Controlled application (2-3 inches)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Diabetes Complications, Diabetes
Diabetic Foot Ulcer and Wound Infection
The goal of the study is to compare whether an integrated model of care between Foot Wound and Diabetes Clinic with use of remote glucose monitoring technology (Intervention Arm), as compared with usual care without the use of…
- Conditions
- Diabetes Complications, Diabetes, Diabetic Foot Ulcer, Wound Infection
- Trial name
- NCT03827902
- Testing
- Telcare 2.0 BGM
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Blister, Wound of Skin
Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.
This is a three-part, Phase I, first-in-human study designed to evaluate the safety, tolerability, and potential systemic exposure of multiple topical doses of TCP-25.
- Conditions
- Blister, Wound of Skin, Epidermolysis Bullosa, Varicose Ulcer of Lower Limb
- Trial name
- NCT05378997
- Where
- Sweden
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Xinnate AB
Diabetic Foot, Lower Limb Wound
Diabetic Foot Care and Limb Preservation Pathway: Developmental Evaluation Study
University Health Network (UHN), working together with local primary care practitioners, patients, and community healthcare services is developing a Diabetic Foot Care and Limb Preservation Care pathway.
- Conditions
- Diabetic Foot, Lower Limb Wound, Diabetes, Amputation
- Trial name
- NCT05446337
- Testing
- Open-Ended Semi-Structured Interview
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Hip Fractures
Comparison of Pericapsular Nerve Group Block With Suprainguinal Fascia Compartment Block in Hip Fractures
Ultrasound-guided Supra-inguinal Fascia Iliaca compartment Block (SIFCB) and Pericapsular Nerve Group Block (PENG) are increasingly being used for postoperative analgesia for hip surgery.
- Trial name
- NCT06169462
- Testing
- PENG block, PENG block+ SIFCB
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Karaman Training and Research Hospital
Behavior, Amputation
Self-Management for Amputee Rehabilitation Using Technology.
Lower Limb Amputations (LLAs) are a substantial burden on the Canadian health services with nearly 50,000 cases reported between 2006 and 2011.
- Conditions
- Behavior, Amputation, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
- Trial name
- SMART (NCT04953364)
- Testing
- SMART, Control
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ischemia Reperfusion Injury, Peripheral Artery Disease
Vitamin B6 on Exercise Pressor Reflex on Leg Ischemia-reperfusion
In this study, we are trying to see if vitamin B6 can minimize the amplified blood pressure response to exercise following ischemia-reperfusion injury.
- Trial name
- NCT06369350
- Testing
- Vitamin B6 25 MG, Vitamin B6 50 MG, Vitamin B6 100 MG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Endothelial Dysfunction
Artery Function Responses to Heat Therapy and Exercise Training
This study will explore the effects of 8 weeks of local leg heat therapy, exercise training, or both on measures of vascular function, cardiorespiratory fitness, and muscle strength in young, healthy individuals.
- Trial name
- NCT04588103
- Testing
- Heat therapy, Exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Non-Diabetic Patients, Wound Leg
Role of Tissue Oxygenation and the miR-210 Gene In Wound Healing
Hypothesis: Elevated miR210 in the epidermis (outer layer of skin) of ischemic human wound edge tissue (tissue that has a lack of blood flow to it) is associated with poor healing outcome in a setting of standard clinical care.
- Conditions
- Non-Diabetic Patients, Wound Leg, Chronic Ulcer Leg/Foot
- Trial name
- miR210 (NCT02024243)
- Where
- 3 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Chandan Sen
Bone Fracture
A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
- Trial name
- NCT05751304
- Testing
- Dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University