Clinical trials: Lower Limb
Spinal Cord Injuries, Rehabilitation
Effects of Walking Training on Different Surfaces on Walking Ability in Ambulatory Patients With Spinal Cord Injury
The study compares effects of 4-week walking training program on a walking track with difference surface [WTDS] and a firm ground on functional ability of ambulatory individuals with incomplete spinal cord injury [iSCI], using…
- Trial name
- NCT03622710
- Testing
- Rehabilitation therapy
- Where
- Thailand
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Aging, Asymmetry
Fall Risk in Adults Over 65: The Relevance of Morphological and Functional Lower Limb Asymmetries.
Falls among older adults represent a major public health burden. Approximately 30% of individuals aged 65 and older experience at least one fall each year.
- Conditions
- Aging, Asymmetry, Fall Risk Factors, Fall Prevention
- Trial name
- ASY&FALL (NCT07742397)
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Leg Veins
Study Comparing Glycerin With 1% Lidocaine and Epinephrine Versus Glycerin With 1% Lidocaine Without Epinephrine for the Sclerotherapy of Leg Telangiectasias
The primary objective is to compare physician-assessed clearance of telangiectatic veins between treatment legs using the Physician Global Aesthetic Improvement Scale (PGAIS).
- Trial name
- NCT07342413
- Testing
- Right leg treated with Glycerin compounded with 1% Lidocaine and Epinephrine, Left leg treated with Glycerin compounded with 1% Lidocaine and Epinephrine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Diabetic Foot, Peripheral Neuropathy With Type 2 Diabetes
The Effects of Different Exercises on Tissue Mechanics, Strength and Neuropathy Symptoms in Type 2 Diabetes Patients
To examine the effects of aerobic exercise and foot exercises in addition to aerobic exercise on lower extremity distal tissue mechanics, muscle strength and neuropathy symptoms in type 2 diabetics with peripheral neuropathy.
- Trial name
- NCT05422235
- Testing
- Routine Medical Treatment, Aerobic Exercise, Aerobic Exercise+ Foot-Related Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Osteoporosis
Clinical Validation of BBCT-hip
The clinical study is aimed at assessing the accuracy of the in silico methodology BBCT-hip. BBCT-hip takes as inputs the subject-specific height and weight, and the CT scan of his femur to predict the risk of fracture for the…
- Trial name
- ValidaBBCT-hip (NCT06270758)
- Testing
- CT scan at the femur
- Where
- 2 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Ankle Injuries
Lateral Ankle Sprain and Platelet Rich Plasma
Lateral ankle sprains are one of the most common in sports medicine. Considering the sprains in general, they represent an 85% of the ankle lesions. The incidence in high performance athletes range from 16 to 21%.
- Trial name
- NCT02609308
- Testing
- Short leg cast, Platelet-rich plasma
- Where
- Mexico
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Venous Leg Ulcer
Diagnostics in the Leg Ulcer Pathway
This project aims to investigate 'The minimum diagnostic requirements for patients presenting to primary care with suspected venous ulcers.' In order to do this, the investigators intend to run a series of questionnaires with…
- Trial name
- NCT06181708
- Testing
- N/A - Questionnaire based study
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Dynamic Tape, Kinesiology Taping
Effects of Dynamic and Kinesiology Taping on Balance and Kinesthesia in Healthy Adults
This study aims to investigate the acute effects of dynamic tape (DT) and kinesiology tape (KT) on balance and kinesthesia of the lower limbs in healthy young adults.
- Trial name
- DAKTIK (NCT06942585)
- Testing
- Kinesiology Tape, Dynamic tape
- Where
- Slovenia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Hip Fractures
Comparative Study to Evaluate the Efficacy of Ultrasound-Guided Pericapsular Nerve Group (PENG) Block Versus Fascia Iliaca Compartment (FIC) Block on the Postoperative Analgesic Effect in Patients Undergoing Hip Surgeries Under Spinal Anesthesia.
Fractures in and around the hip are quite common irrespective of both the young and elderly population groups and are associated with extreme pain.
- Trial name
- NCT05751291
- Testing
- Bupivacaine Hydrochloride
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sohag University
Balance and Gait Impairment in Elderly Women
Effects of Water Inertia Load Training on Lower Limb Joint Moments, Gait, and Balance in Elderly Women
This study highlights that age-related neuromuscular changes negatively impact muscle strength, balance, joint mobility, and cardiovascular health, which in turn affect daily life activities and independence.
- Trial name
- NCT06705946
- Testing
- Aqua vest group, Weight vest group
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hyun Ju Kim
Lower Limb Deformity, Anterior Knee Pain Syndrome
Is Gait Analysis for Proposed Rotational Deformities a Useful Resource
Rotational deformities, such as femoral (thigh bone) and tibial (leg bone) torsion, are established causes of patellofemoral (kneecap joint) pain and instability.
- Conditions
- Lower Limb Deformity, Anterior Knee Pain Syndrome, Patellofemoral Pain, Rotation; Deformity
- Trial name
- NCT05576064
- Testing
- Gait analysis
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction
Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People
Comparison of kinematic movements between patients with anterior cruciate ligament rupture and post-operative patients and normal people using a mobile dynamic X-ray device.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction, Healthy People
- Trial name
- NCT05619393
- Testing
- Mobilie Bi-planar X-ray Imaging system
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wang Joon Ho
Anterior Cruciate Ligament Injuries, Knee Injuries
Evaluation of Vastus Medialis Muscle Inhibition in Indoor Soccer Players With and Without ACL Injury
The Anterior Cruciate Ligament (ACL) is vital for knee stability, and ACL injuries in futsal can lead to long-term issues. Reconstruction surgery may be affected by Anthrogenic Muscle Inhibition (AMI), especially in the vastus…
- Trial name
- NCT06599164
- Testing
- Anthrogenic Muscle Inhibition (AMI) Assessment Protocol
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque
This study will investigate the reliability and validity of an inline 'pull-type' dynamometer for measuring peak knee extensor torque.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05109871
- Testing
- KForce Link
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
The Effectıveness Of Structured Myofascial Chain Exercise Training After Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament reconstruction(ACLR) surgery accepts best choices which condicions are totaly ruptured ACL or partial ruputures when patients with high activity level.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT05423184
- Testing
- Exercise Therapy For Lower Extremities, Exercise Therapy For Myofascial Chains
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Diabetes Mellitus, Type 2, Diabetic Foot
Prostacyclin (PGI2) Pathway to Enhance Wound Healing in Diabetic Foot Ulcers
Prospective, monocentric, pathophysiological study, comparing 3 parallel groups: healthy controls; patients with diabetes and without DFU; patients with diabetes and with DFU.
- Trial name
- PGI2HEAL (NCT05099367)
- Testing
- Microdialysis, current induced vasodilation, Skin biopsy, peri-ulcerated skin biopsy
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Older Adults
Effects of Home-based Lower Extremity Muscle Power Training on Functional Muscle and Balance Performance in Older Adults
Background: Muscle power, defined as the rate at which muscular force is generated to produce movement, declines more rapidly with age than muscle strength.
- Trial name
- NCT06901700
- Testing
- Experimental Group, control group
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Cognitive Functioning of Healthy Individuals, Balance
Task-Specific Training vs. Yoga (With and Without Perturbation) for Balance and Leg Strength in Older Adults
This experimental study is designed to observe the effectiveness of task-specific training vs yoga with and without perturbation on reactive balance and leg strength in older individuals in Islamabad/Rawalpindi, Pakistan.
- Conditions
- Cognitive Functioning of Healthy Individuals, Balance, Strength, Muscle, Quality of Life (QOL)
- Trial name
- NCT06875388
- Testing
- Task specific Training, Specific Yoga Poses, Tasl specific Training with perturbation
- Where
- Pakistan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shifa Tameer-e-Millat University
Venous Ulcers
Effect of Compressive Therapies on the Healing of Venous Ulcers
The objective of the study is to compare the effect of two treatments on the healing of venous ulcers in follow-up people in two Primary Health Services, in a city in southern Brazil.
- Trial name
- VENOS (NCT04703569)
- Testing
- Dressing with monolayer high compression elastic bandage, Dressing with Unna boot
- Where
- 3 sites in Brazil
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
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