Clinical trials: Lower Urinary Tract Infection
Urinary Tract Infections
Comparison of Pre-procedural PCR and Culture-based UTI Assessment Prior to Intravesical Botox Injection
This study is a retrospective record review to determine whether a novel multiplex PCR assay can be utilized as a screening method for UTI in patients receiving Botox injection to treat overactive bladder (OAB).
- Trial name
- NCT04817865
- Testing
- Multiplex-PCR with Pooled Antibiotic Susceptibility Testing (M-PCR/P-AST), Urine Culture
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pathnostics
Overactive Bladder, Bladder Pain Syndrome
Bladder Botox UTI Antibiotic Prophylaxis
Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life.
- Trial name
- NCT06387329
- Testing
- Nitrofurantoin 100 MG
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Urinary Tract Infections, Urinary Tract Infection Lower Acute
Management of Acute Uncomplicated UTIs in Adults by Community Pharmacists
This study is to be conducted in community pharmacies. It involves the use of trained mystery patients to evaluate community pharmacists at baseline and post intervention.
- Trial name
- [UTI] (NCT05399797)
- Testing
- Educational training
- Where
- Nigeria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Urinary Tract Infections
Nitrofurantoin and Urinary Tract Infections (UTIs)
Urinary tract infection (UTI) is the most common complication after surgery for prolapse or urinary incontinence. UTIs are painful and have the potential to turn into kidney infections.
- Trial name
- APPIC (NCT00678041)
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Neurogenic Bladder, Neurogenic Bowel
The Role of Active Administration of Peristeen Bowel Evacuation for the Management of Urinary Tract Infection
This study investigates whether active use of transanal irrigation (Peristeen®) effectively manages urinary tract infection among patients with the diagnosis of neurogenic bladder.
- Conditions
- Neurogenic Bladder, Neurogenic Bowel, Spina Bifida, Fecal Incontinence
- Trial name
- NCT04815226
- Testing
- Peristeen Transanal Irrigation
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Pelvic Organ Prolapse, Urinary Incontinence
Chlorhexidine vs. Iodine for Vaginal Preparation in Urogynecologic Procedures
This is a randomized controlled trial to determine if there is a difference between chlorhexidine gluconate and povidone iodine vaginal preparations for urogynecological surgery post operative infections.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Pelvic Floor Disorders, Gynecologic Disease
- Trial name
- CLNUP (NCT04048356)
- Testing
- Vaginal scrub, to be applied vaginally and perineally immediately prior to surgery.
- Where
- United States
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Neurogenic Bladder Disorder, Lower Urinary Tract Disorder
Rapid UTI Diagnostics in Lower Urinary Tract Dysfunction Among Catheter Users
Patients who seek care through MedStar National Rehab Hospital's clinic believing they have a UTI will be enrolled in this trial.
- Conditions
- Neurogenic Bladder Disorder, Lower Urinary Tract Disorder, Urinary Tract Infection (Diagnosis)
- Trial name
- NCT07784829
- Testing
- urine Resazurin Reduction Ratio, USQNB
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Urologic Injuries, Urologic Diseases
Bladder Morphology Using 2 Different Catheter Designs
Demonstrate and compare the 3D morphology of the bladder wall in full and drained states with 2 different kinds of bladder catheters in place. (Foley Catheter vs. Cystosure Catheter)
- Conditions
- Urologic Injuries, Urologic Diseases, Bladder Infection, Urinary Tract Infections
- Trial name
- NCT03108079
- Testing
- Cystosure Urinary Access System, Foley Catheter
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Pelvic Floor Institute
HIV Seropositivity, Lower Urinary Tract Symptoms
Lower Urinary Tract Symptoms in Males Living With HIV
The primary aim of this study is to learn whether the frequency of lower urinary tract symptoms differ between the males with seronegativity for HIV and males living with HIV.
- Trial name
- NCT05964803
- Testing
- Questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Koç University
Stress Incontinence
Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence
This project will determine whether post-operative prophylaxis with macrobid will decrease the incidence of postoperative urinary tract infection in women receiving sub-urethral slings for the treatment of urinary incontinence.
- Trial name
- NCT00734968
- Testing
- Nitrofurantoin
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
UTI, Female Urogenital Diseases
Methenamine in a Non-antibiotic, Multimodal Approach to UTI Prevention
Urinary tract infections (UTIs) are the most common bacterial infection and are especially common in postmenopausal women, who often experience recurrent UTIs.
- Conditions
- UTI, Female Urogenital Diseases, UTI - Lower Urinary Tract Infection
- Trial name
- NCT03996057
- Testing
- Methenamine Hippurate 1000 MG, Vaginal estrogen, D-mannose
- Volunteers
- healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Urinary Dysfunction, Lower Urinary Tract Symptoms
School-Based Bladder Health Intervention
The aim of this study is to promote healthy bladder behaviors among school children. We hypothesize that a combination of bladder health education and awareness events, additional resources such as a water station to support…
- Conditions
- Urinary Dysfunction, Lower Urinary Tract Symptoms, Urinary Tract Infections, Urinary Tract Infections in Children
- Trial name
- NCT06273098
- Testing
- Bladder Health Education
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Overactive Bladder
Bacterial Genomic Sequencing in Overactive Bladder
No one really knows what causes overactive bladder syndrome (OAB). Urinary tract infection (UTI)causes similar symptoms to OAB with the difference being the presence of bacteria, as evidenced by routine microbiology cultures.
- Trial name
- NCT01642277
- Testing
- Solifenacin
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Loyola University
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Antibiotic Stewardship, Overactive Bladder
Antibiotic Usage Prior to OnabotulinumtoxinA Injection
Intradetrusor injection of onabotulinumtoxinA, which is performed through a cystoscopic procedure, has been demonstrated to be efficacious in the treatment of both neurogenic and non-neurogenic overactive bladder (OAB), and is…
- Conditions
- Antibiotic Stewardship, Overactive Bladder, Onabotulinumtoxin A, UTI
- Trial name
- NCT04754737
- Testing
- No antibiotic, Prophylactic antibiotic, cystoscopic injection of onabotulinumtoxinA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Overactive Bladder, Urinary Tract Infection
Urinary Cytokines in Patients With Overactive Bladder (OAB)
Overactive bladder (OAB) is a widespread condition characterized by urgency, urge incontinence, nocturia and excessive urinary frequency, affecting millions of people worldwide.
- Trial name
- NCT00868621
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Lower Urinary Tract Symptoms, Lower Urinary Tract Infection
PEEZY Midstream Urine Device Compared to Catheterized Urine Sample
Urine culture and microscopic urinalysis will be compared between 2 collection methods: PEEZY midstream urine collection, and urethral catheter collection.
- Trial name
- PEEZY (NCT03729336)
- Testing
- Midstream urine collection device, Catheter for urine collection
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Urinary Tract Infection, Leiomyoma
Lower Urinary Tract Infection (UTI) Evaluation in Women With Uterine Leiomyomata
To the investigators knowledge there is no research data published to date regarding the lower urinary tract symptoms in women with leiomyomas. The primary aims of this study are: 1.
- Trial name
- LOTUS (NCT01123603)
- Where
- United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Urinary Retention, Urinary Incontinence
Reducing Postoperative Catheterization
After reconstructive pelvic surgery urinary retention occurs in up to 60% of patients requiring an indwelling catheter or self-catheterization (1-5).
- Conditions
- Urinary Retention, Urinary Incontinence, Pelvic Organ Prolapse, Urinary Tract Infections
- Trial name
- NCT03009968
- Testing
- Post-void residual free voiding trial
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill