Clinical trials: Lumbago
Osteoarthritis, Rheumatoid Arthritis
Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain
The purpose of this study is to assess the efficacy of the buprenorphine transdermal patch (Norspan® or Sovenor® transdermal patch) in patients with chronic non-malignant pain of moderate to severe intensity due to…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Lower Back Pain, Joint Pain
- Trial name
- NCT01961271
- Testing
- Buprenorphine transdermal patch
- Where
- 16 sites in Hong Kong, Philippines and 1 more
- Volunteers
- 114 people
- Sponsor
- Mundipharma Pte Ltd.
Chronic Low-back Pain
Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain
This study is being done to test the safety and efficacy of the study drug LY3556050 for the treatment of chronic low back pain.
- Trial name
- NCT04874636
- Testing
- LY3556050
- Where
- 35 sites in United States, Puerto Rico
- Volunteers
- 153 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study to Evaluate Long-Term Safety of Multiple Doses of Tapentadol (CG5503) Prolonged-Release (PR) and Oxycodone Controlled-Release (CR) in Patients With Chronic Pain
The purpose of this study is to evaluate the safety profile of tapentadol (CG5503) PR at doses of 100 mg - 250 mg administered twice daily over a maximum one year period to patients with at least a 3-month history of low back…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Knee, Lower Back Pain, Pain
- Trial name
- NCT00361504
- Testing
- Oxycodone CR, Tapentadol (CG5503) ER
- Where
- 52 sites in United States, Canada
- Volunteers
- 1,123 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Chronic Low Back Pain
Reducing Sedentary Behavior to Decrease Low Back Pain: Stand Back Study
This study will test the effects of a sedentary behavior intervention on low back pain in working adults. The behavioral intervention will include the use of a sit-stand desk and a wrist-worn activity prompter that will notify…
- Trial name
- StandBack (NCT02624687)
- Testing
- Intervention, No intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
Back Pain Without Radiation, Low Back Pain
A Comparison of NSAIDs for Acute, Non-radicular Low Back Pain.
Purpose: This is a randomized clinical trial comparing the effects of three different medications for acute low back pain (LBP):Ketorolac, Ibuprofen, Diclofenac Hypothesis: A daily regimen of ketorolac will provide greater relief…
- Trial name
- NCT03861611
- Testing
- Ketorolac, Ibuprofen, Diclofenac
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Montefiore Medical Center
Low Back Pain
Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Naive Subjects
The purpose of this study is to determine if buprenorphine hydrochloride (HCl) buccal film is effective in treating opioid-naive subjects, with moderate to severe chronic low back pain (CLBP), who require continuous…
- Trial name
- NCT01633944
- Testing
- Buprenorphine
- Where
- 60 sites in United States
- Volunteers
- 752 people
- Sponsor
- BioDelivery Sciences International
Low Back Pain
Mechanisms of Specific Trunk Exercises in Low Back Pain
The research objective is to determine which physical therapy (PT) treatment is the most efficacious for patients with lower back pain (LBP), who have been subgrouped based on certain clinical features.
- Trial name
- NCT01362049
- Testing
- Physical Therapy rehabilitation: Stabilization exercises., Physical Therapy rehabilitation. Movement System Impairment (MSI) classification based exercise
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Vermont
Chronic Low-back Pain
The Back Pain Consortium Research Program Study
This study is being completed to better understand who benefits from different chronic pain treatments and how these treatments work. This study will include a four week run-in period for all cLBP participants.
- Trial name
- BACPAC (NCT04870957)
- Testing
- PainGuide, MBSR, PT and exercise
- Where
- United States
- Volunteers
- 494 people
- Sponsor
- University of Michigan
Chronic Pain
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate efficacy of hydrocodone extended-release (ER) tablets compared with placebo in alleviating moderate to severe pain in patients with osteoarthritis or low back pain as assessed by…
- Trial name
- NCT01240863
- Testing
- Hydrocodone ER
- Where
- 73 sites in United States
- Volunteers
- 391 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Pain, Low Back Pain
An Efficacy and Safety Study for Tapentadol Extended Release (JNS024ER) in Chronic Pain Participants
The purpose of this study is to evaluate the efficacy, safety and to explore the pharmacokinetics (how drugs are absorbed in the body, how they are distributed within the body and how they are removed from the body over time) of…
- Conditions
- Pain, Low Back Pain, Back Pain, Osteoarthritis, Knee
- Trial name
- NCT01124604
- Testing
- Tapentadol Hydrochloride
- Where
- 19 sites in Japan
- Volunteers
- 91 people
- Sponsor
- Janssen Pharmaceutical K.K.
Low Back Pain
EMG Activation of Gluteal Musculature During Exercises With and Without Resistance
The gluteus medius (Gmed) and gluteus maximus (Gmax) muscles are important components in the treatment of many lower limb injuries.
- Trial name
- GlutEMG02 (NCT01841216)
- Testing
- Lower Body Exercises with and without resistance
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Low Back Pain
The Effect of Lumbar Stabilization Exercise and Gait Training on Lower Back Muscles- Electromyographic(EMG) Analysis
The purpose of this study is to determine the effective exercise protocol in chronic low back pain patients.
- Trial name
- EMG (NCT02938169)
- Testing
- exercise
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Chronic Low-back Pain
Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Chronic Low Back Pain
This study is being done to test the safety and efficacy of the study drug LY3016859 for the treatment of chronic low back pain.
- Trial name
- NCT04529096
- Testing
- LY3016859
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 149 people
- Sponsor
- Eli Lilly and Company
Low Back Pain, Chronic Pain
Efficacy and Safety Study of NKTR-181 in Opioid-Naive Subjects With Low Back Pain
The purpose of this study is to determine whether a new opioid molecule, NKTR-181, is effective for the relief of moderate to severe chronic low back pain as compared to a placebo.
- Trial name
- SUMMIT-07 (NCT02362672)
- Testing
- NKTR-181 BID tablets
- Where
- 54 sites in United States
- Volunteers
- 1,189 people
- Sponsor
- Nektar Therapeutics
Low Back Pain
Effectiveness of Percutaneous Lumbar Epidural Adhesiolysis and Neurolysis on Low Back Pain
Clinically significant improvements in the percutaneous adhesiolysis patients with hypertonic neurolysis compared to those patients randomized to the control group who did not receive adhesiolysis and hypertonic saline…
- Trial name
- NCT00370994
- Testing
- Caudal epidural injection, Percutaneous adhesiolysis
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Chronic Low Back Pain, Fear of Pain
The VIGOR Study - Virtual Immersive Gaming to Optimize Recovery in Low Back Pain
This study will measure the effects of interactive, whole-body video games on movement behavior in people with chronic low back pain.
- Conditions
- Chronic Low Back Pain, Fear of Pain, Fear of Injury
- Trial name
- VIGOR (NCT03463824)
- Testing
- Experimental Group 1, Experimental Group 2
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Virginia Commonwealth University
Lower Back Pain, Lumbar Radiculopathy
Virtual Reality as a Substitute for Procedural Sedation During Epidural Steroid Injections
This study examines the impact of virtual reality compared to sedation (midazolam and/or fentanyl) and no intervention on pain experienced from an epidural steroid injection (ESI).
- Trial name
- NCT04887285
- Testing
- Virtual reality, Intravenous sedation, Standard care
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Johns Hopkins University
Low Back Pain
Efficacy and Safety of Oxycodone/Naloxone Controlled-release Tablets (OXN) Compared to Placebo in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain
The primary objective of this study is to assess the efficacy and safety of OXN compared to placebo in opioid-experienced subjects with moderate to severe pain due to chronic low back pain who require around-the-clock opioid…
- Trial name
- NCT01358526
- Testing
- Oxycodone/Naloxone Controlled-release
- Where
- 151 sites in United States
- Volunteers
- 1,095 people
- Sponsor
- Purdue Pharma LP
Low Back Pain
Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Chronic Low Back Pain
The objective of this study is to determine the analgesic efficacy and safety of Buprenorphine Transdermal System (BTDS) 10 and 20 compared to placebo in opioid-naïve subjects with moderate to severe chronic low back pain.
- Trial name
- NCT00490919
- Testing
- Buprenorphine transdermal system
- Where
- 86 sites in United States
- Volunteers
- 539 people
- Sponsor
- Purdue Pharma LP