Clinical trials: Lumbar Facet Joint Pain
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Spinal Minimally Invasive and Interventional Surgeries
Application of 3D printing guide plate in spinal minimally invasive and interventional surgeries
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radiculopathy, Lumbosacral Facet Joint Syndrome
- Trial name
- NCT05487690
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Chronic Low-back Pain, Lumbar Facet Joint Syndrome
Comparison of the Effectiveness of Ultrasound-guided Versus Radioguided Medial Lumbar Bundle Branch Block
In adults with chronic low back pain, the investigators will compare the effectiveness of the medial bundle branch block on three lumbar levels (L3-L4, L4-L5 and L5-S1) performed either by radiographic guidance or by ultrasound…
- Trial name
- NCT04658953
- Testing
- Ultrasound guided infiltration, Fluoroscopy guided infiltration
- Where
- 3 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Low Back Pain, Zygapophyseal Joint Arthritis
Endogenous Opioid Response to Injections
This study will study pain relief after spine injections that are used to guide care. Some improvements in pain from a procedure might be from placebo effect rather than the physiological effect of the procedure.
- Trial name
- AEOUI2 (NCT06666621)
- Testing
- Normal saline infusion, Naloxone infusion
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Middle Tennessee Research Institute
Chronic Lower Back Pain (CLBP), Lumbar Facet Joint Pain
Lumbar Facet Platelet-Rich Plasma Injection Versus Medial Branch Radiofrequency Ablation for Chronic Lumbar Facet-Mediated Pain
The first clinical research effort under this initiative is a pilot randomized controlled trial comparing intra-periarticular lumbar facet platelet-rich plasma (PRP) injection to standard-of-care medial branch radiofrequency…
- Trial name
- NCT07692737
- Testing
- Platelet Rich Plasma Joint Injection, Medial branch radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- The New England Baptist Hospital
Chronic Lower Back Pain, Lumbar Facet Syndrome
A Trial of Intravenous Paracetamol vs. Placebo in Patients Receiving Radiofrequency Ablation of the Medial Branch Facet Nerve
A double blinded randomized controlled study comparing pre-procedural IV Paracetamol versus IV placebo (normal saline). The patients will be randomized to either receiving IV paracetamol or saline infusions before undergoing…
- Trial name
- NCT02539979
- Testing
- Paracetamol
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Facet Joint Arthropathy, Lower Back Pain
Association Between Trendelenburg Sign and Lumbar MRI Abnormalities
The Trendelenburg sign is a common clinical finding indicating hip abductor dysfunction and altered pelvic stability. The relationship between the Trendelenburg sign, spinopelvic biomechanics, hip muscle strength, and lumbar…
- Trial name
- NCT07629466
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bahçeşehir University
Chronic Pain, Facet Joint Pain
Sensory Mapping of Lumbar Facet Joint Pain
Low back pain is a major contributor to the chronic pain burden in the community. Although there are numerous pain generators in the spine, lumbar facet joints are one of the most common sources of pain.
- Trial name
- SENS-MAP (NCT03323775)
- Testing
- Suprathreshold stimulation
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Aberdeen
Lumbar Facet Joint Pain
One-Needle Vs Three-Needle Radiofrequency in Low Back Pain Due to Facet Joint Arthritis
Failure of RFA has been attributed to technical failure of coagulating the nerve or coagulation of a minimal section of the nerve, allowing for early reinnervation.
- Trial name
- NCT05137652
- Testing
- Radiofrequency ablation of medial nerve using single needle approach, Radiofrequency ablation of medial nerve using three needle approach
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Lumbar Facet Joint Pain
MR Guided High Intensity Focused Ultrasound for Lumbar Back Pain
The primary purpose of this protocol is to assess the ExAblate 2100 MR guided high intensity focused ultrasound device as an intervention for treatment of facetogenic lower back pain.
- Trial name
- NCT02291978
- Testing
- ExAblate 2100
- Where
- United States
- Sponsor
- Stanford University
Facet Joint Syndrome
Multifidus Muscle Twitch on the Prognosis of Lumbar Medial Branch RF
The investigators collected data and chart from the patients who were diagnosed facet joint syndrome and underwent lumbar RF medial branch neurotomy between January 2009 and June 2014.
- Trial name
- NCT02580383
- Testing
- Radiofrequency neurotomy of lumbar medial branch
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Severance Hospital
Facet-Mediated Low Back Pain
Allogeneic BM-MSCs in Patients with Lumbar Facet Arthropathy
Researchers are conducting this study to learn more about the side effects of bone marrow-derived stem cells when injected into the facet joints for the treatment of painful lumbar facet joint arthropathies.
- Trial name
- Cellkine (NCT04410731)
- Testing
- Single bilateral intra-articular injection of allogeneic BM-MSCs for lumbar facet joint arthropathy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Pain Measurement
Pain Assessment Via Force Measurement Using eEgg After Blockade of the Lumbar Facet Joints
The emotion Egg, or "eEgg" for short, is a sample series of a device for testing a new pain measurement method that is not yet on the market.
- Trial name
- SMeEgg (NCT05881551)
- Testing
- eEgg, NRS
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- University of Witten/Herdecke
Low Back Pain, Osteoarthritis
Platelet-rich Plasma Infiltration Versus Corticosteroid Infiltration (Prednisolone) in Treatment of Lumbar Facet Joint Syndrome
The prevalence of low back pain is estimated at 90% . Recent studies have shown that 15% to 52% of back pain is attributable to facet joint syndrome .
- Trial name
- IAPRP (NCT05105256)
- Testing
- Prednisolone, Platelet-rich plasma
- Where
- France
- Volunteers
- 76 people
- Sponsor
- CHU de Reims
Low Back Pain
A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome
This study is being done to determine whether cooled radiofrequency ablation (CRFA) on the medial branch nerves of the lumbar facet joint is effective for the treatment of low back pain.
- Trial name
- STU00097239 (NCT02478437)
- Testing
- Conventional radiofrequency ablation (RFA), Cooled Radiofrequency Ablation (CRFA)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Northwestern University
Low Back Pain
FDG PET/MRI Evaluation of Facet Joint Pain
Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints.
- Trial name
- NCT02921490
- Testing
- FDG PET/MR examination.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Degenerative Disc Disease, Discogenic Low Back Pain
A Comparative Study Between Mechanical and a Viscoelastic Disc Prosthesis in the Lumbar Spine
TDR implants for the lumbar spine are currently most 2- or 3-piece devices with a purely mechanical function that provide/restore mobility.
- Trial name
- NCT03716947
- Testing
- Device: ZACK, Device: ORBIT, Device: SASCA
- Where
- Sweden
- Volunteers
- 246 people
- Sponsor
- Karolinska Institutet
Facet Joint Pain; Low Back Pain
Sidekick vs Conventional Cannula in Lumbar Medial Branch Radiofrequency Ablation
Lumbar facet joint-mediated chronic low back pain is a common cause of disability. Radiofrequency ablation (RFA) of the lumbar medial branches is an established interventional pain treatment.
- Trial name
- SIDE-RFA (NCT07475689)
- Testing
- Lumbar Medial Branch Radiofrequency Ablation, Triamcinolone (20 g), bupivacain 0.5% 2ml
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Chronic Low Back Pain, Lumbar Facet Joint Degeneration
Association of Subcutaneous Fat Index, Paraspinal Muscle Characteristics, and Facet Morphology With Lumbar Facet Joint Degeneration
This prospective observational study aims to investigate the association between subcutaneous fat index, paraspinal muscle characteristics, facet morphology, and lumbar facet joint degeneration in adults with chronic low back…
- Trial name
- NCT07860697
- Testing
- Lumbar Magnetic Resonance Imaging (MRI)
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Marmara University
Degenerative Disc Disease, Back Pain Lower Back Chronic
The SPINUS II Study: Spinal Fusion for Multilevel SPECT/CT Positive Lumbar Degeneration
The aim of the present study is to find out whether fusion of multilevel SPECT/CT positive lumbar degeneration leads to a significant improvement of pain and disability.
- Conditions
- Degenerative Disc Disease, Back Pain Lower Back Chronic, Facet Joint Arthropathy, Facet Syndrome of Lumbar Spine
- Trial name
- NCT04893720
- Testing
- Lumbar fusion
- Where
- 2 sites in Czechia
- Volunteers
- 30 people
- Sponsor
- Military University Hospital, Prague
Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence
Quantitative Assessment of Lumbar Facet Joint Degeneration, A Retrospective Study.
Observational study The purpose of this observational study was to understand the quantitative assessment of the degree of degeneration of lumbar facet joints, and to improve the Weishaupt grading system by using gray-scale curve…
- Conditions
- Facet Joint Pain; Low Back Pain, Facet Joints; Degeneration ; Deep Learning ;Artificial Intelligence, Facet Joint Disease
- Trial name
- NCT06786611
- Testing
- MRI
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Changzheng Hospital