Clinical trials: Lumbar Fusion Surgery
Older Adults (60 - 85 Years Old), Sarcopenia
Evaluation of Sarcopenia and Muscle Biomechanics in Older Adults After Lumbar Fusion Surgery
Abstract Background: Lumbar fusion (LF) surgery successfully restores the mechanical stability of the spine; however, postoperative kinesiophobia and complications can trigger secondary sarcopenia.
- Conditions
- Older Adults (60 - 85 Years Old), Sarcopenia, Lumbar Fusion Surgery, Low Back Pain
- Trial name
- NCT07866807
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Karamanoğlu Mehmetbey University
Transforaminal Lumbar Interbody Fusion Surgery
The Objective of the Protocol is to Generate Real World Evidence (RWE) Supporting the Safety, Performance, and Health Economics of Using the Regulatory Approved and Commercially Available EARP Interbody System Used During Lumbar Interbody Fusion (LIF) Procedures With the EARP Nerve Cuff Electrode
The goal of the trial is to generate data to support the safety, performance, and cost effectiveness of using the EARP devices during Lumbar Interbody Fusion (LIF) procedures.
- Trial name
- EARP-2 (NCT07020000)
- Testing
- Device: Nerve Cuff and Retractor System
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- Retropsoas Technologies, LLC
Lumbar Fusion Surgery
ITM vs ITM+Clonidine for Lumbar Fusions
Dr. Parker Merrill (anesthesiologist) and Dr. Chris Neal (neurosurgeon) are working on a research study comparing two methods of pain control for patients having spinal fusion surgery.
- Trial name
- NCT07846657
- Testing
- Intrathecal Morphine + Intrathecal Clonidine, Intrathecal Morphine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- MaineHealth
Lumbar Fusion Surgery
Intravenous Lidocaine Infusion in Lumbar Fusion Surgery
Elective lumbar fusion surgery is associated with moderate to severe postoperative pain and often requires substantial perioperative opioid administration.
- Trial name
- NCT07488832
- Testing
- Lidocaine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Single Level Lumbar Decompression and Fusion Spine Surgery
Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study
The purpose of this study is to determine if post-operative pain and rate of recovery are improved in patients undergoing spine surgery using MMA (multimodal analgesia) compared to usual analgsic care.
- Trial name
- NCT02202369
- Testing
- Multimodal Analgesia Treatment, Standard of Care Pain Management Protocol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Surgical Blood Loss, Postoperative Pain
PVI vs ESP Block for Reducing Bleeding and Postoperative Pain in Lumbar Fusion Surgery.
This randomized controlled trial compares periarticular vasoconstrictor infiltration (PVI) versus erector spinae plane block (ESP) to reduce bleeding and postoperative pain in adults undergoing lumbar fusion surgery (up to 3…
- Conditions
- Surgical Blood Loss, Postoperative Pain, Lumbar Spinal Fusion Surgery
- Trial name
- NCT07550114
- Testing
- Periarticular vasoconstrictor infiltration (PVI), Erector Spinae Block (ESP)
- Where
- 2 sites in Spain
- Volunteers
- 62 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Lumbar Fusion Surgery, Elderly Patients
Clinical Impact of Different Crystalloid Solution on Early Biomarkers of Kidney Injury After Lumbar Fusion Surgery in Elderly Patients
This study aims to compare the effects of sodium acetate Ringer's solution versus sodium lactate Ringer's solution on early postoperative renal function indicators, renal injury biomarkers, and acute kidney injury (AKI) in…
- Conditions
- Lumbar Fusion Surgery, Elderly Patients, Sodium Acetate Ringer's Solution, Sodium Lactate Ringer's Solution
- Trial name
- NCT07542353
- Testing
- Sodium Acetate Ringer's Solution (Group A), Sodium Lactate Ringer's Solution (Group B)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Xianping Wu
Transforaminal Lumbar Interbody Fusion Surgery
A Post-marketing Study to Evaluate a Novel Surgical Monitoring Technique Using the EARP Nerve Cuff in TLIF Surgery.
The purpose of this study is to evaluate the differences (the effectiveness and the safety) between two different nerve and muscle monitoring devices currently available during a TLIF surgery.
- Trial name
- NCT06204900
- Testing
- Nerve Cuff and Retractor System
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Retropsoas Technologies, LLC
Lumbar Fusion Surgery
IO Vancomycin Spine
The goal of this research is to learn if injecting the antibiotic vancomycin directly into the bone marrow (intraosseous) or IO) during a lumbar (spinal) fusion surgery, is as effective or better than the standard method of…
- Trial name
- NCT06748144
- Testing
- Intraosseous Vancomycin, Intravenous Vancomycin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Methodist Hospital Research Institute
Postoperative Pain Management, Lumbar Spinal Fusion Surgery
Single- Versus Two-Level ESP Block for Analgesia After Lumbar Stabilization Surgery
Lumbar stabilization surgery is commonly associated with moderate to severe postoperative pain. Effective pain control is important to improve patient comfort, early mobilization, and recovery.
- Conditions
- Postoperative Pain Management, Lumbar Spinal Fusion Surgery, Erector Spina Plan Block
- Trial name
- ESP-Lumbar (NCT07363096)
- Testing
- Single-Level Erector Spinae Plane Block, Two-Level Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Lumbar Spine Fusion Surgery
Multimodal GA for Lumbar Spine Surgery
To evaluate the effects of multimodal general anesthesia on the recovery profile of elder patients undergoing lumbar spine fusion surgery.
- Trial name
- NCT05247177
- Testing
- dexmedetomidine, ketamine co-administration with sevoflurane for general anesthesia, Conventional general anesthesia by administration of sevoflurane alone
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Spinal Stenosis Lumbar, Disc Degeneration
Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF
Researchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and…
- Conditions
- Spinal Stenosis Lumbar, Disc Degeneration, Disc Disease, Fusion of Spine
- Trial name
- MIS-TLIF (NCT06367855)
- Testing
- Dexamethasone, Normal saline
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Potsawat Surabotsopon
Lumbar Fusion Surgery, Fusion of Joint
Evaluation of the Efficacy and Safety of Absorbable vs Traditional Bone Wax for Facet Fusion After Lumbar Fusion Surgery
Hemorrhage on the surface of cancellous bone presents a significant challenge in orthopedic surgery. Traditional bone wax, commonly utilized for hemostasis in bone wounds, is non-absorbable and associated with various…
- Trial name
- NCT07040293
- Testing
- Absorbable bone wax for hemostasis in the osteotomy surface of the facet joint, Traditional bone wax for hemostasis in the osteotomy surface of the facet joint
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Shanghai Changzheng Hospital
Percutaneous Pedicular Screw (PPS) Fixation, Minimally Invasive Transforaminal Lumbar Interbody Fusion (MIS TLIF) Surgeries
Comparison of Thoracolumbar Interfascial Plane Block (TLIP-block) and Local Anesthetic (LA) Infiltration in Minimally Invasive Spine Surgery: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effectiveness of the thoracolumbar interfascial plane block (TLIP block) versus local anesthetic (LA) infiltration in managing postoperative pain in minimally invasive surgery…
- Trial name
- NCT06761079
- Testing
- Thoracolumbar interfascial plane block, Local anesthetic infiltration
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Lumbar Fusion Surgery
Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery
The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the lumbar fusion surgery.
- Trial name
- NCT04983966
- Testing
- Desflurane, Remimazolam
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Enhanced Recovery After Surgery, Spinal Fusion
Enhanced Recovery After Surgery in Oblique Lumbar Interbody Fusion
This study is a randomized controlled non-inferiority trial designed to evaluate the impact of implementing the 'Early Recovery After Surgery Clinical Pathway (ERAS CP)' on patient-reported pain levels at the time of discharge…
- Conditions
- Enhanced Recovery After Surgery, Spinal Fusion, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- NCT05959343
- Testing
- Enhanced Recovery After Surgery program for Oblique Lumbar Interbody Fusion
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Seoul National University Hospital
Erector Spinae Block, Lumbar Fusion Surgeries
Adding Dexmedetomidine to Bupivacaine for Bilateral Erector Spinae Block
The aim of this study is to compare the analgesic effect of bilateral US-guided ESPB using bupivacaine alone versus bupivacaine and DEX in lumbar fusion surgeries.
- Conditions
- Erector Spinae Block, Lumbar Fusion Surgeries, Dexmedetomidine
- Trial name
- NCT06231979
- Testing
- Dexmedetomidine, Bupivacain, Normal saline
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Fusion, Radiculopathy Lumbar
SynerFuse Spinal Fusion and Neuromodulation Proof of Concept Study
The purpose of the study is to evaluate the safety and tolerability of DRG stimulation when placing a neurostimulator during the same procedure as implantation of spinal fixation with or without interbody cage systems in patients…
- Conditions
- Spinal Fusion, Radiculopathy Lumbar, Chronic Pain
- Trial name
- NCT04054401
- Testing
- DRG Neurostimulation with Spinal Fusion
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- SynerFuse, Inc