Clinical trials: Lumbar Fusion Surgery
Lumbar Fusion, Lumbar Spinal Fusion Surgery
Clinical and Biomechanics Research in Core Muscles After Lumbar Fusion Surgery
Lumbar fusion has been widely used for spinal disorders when conservative treatment has failed. However, a number of studies have reported that the rate of re-operation is high for lumbar fusion surgery.
- Trial name
- NCT01703338
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Back Pain, Fusion of Spine, Lumbar Region
The Comparison of Postoperative Pain After Lumbar Fusion Surgery in Intravenous Patient-controlled Analgesia Between Conventional Mode and Optimizing B.I Mode With 'PAINSTOP' Equipment
The postoperative pain of lumbar fusion surgery is very severe that it is necessary to use additional analgesics as well as a patient controlled analgesia (PCA).
- Conditions
- Back Pain, Fusion of Spine, Lumbar Region, Spinal Stenosis
- Trial name
- NCT03047044
- Testing
- Optimizing basal infusion (B.I), Conventional PCA mode
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Degenerative Spine Diseases
Minimal Invasive Transforaminal Lumbar Interbody Fusion for Degenerative Lumbar and Lumbosacral Spine Diseases
The aim of this study is to evaluate clinical and surgical outcome of MI-TLIF for degenerative lumbar and lumbosacral spine diseases.
- Trial name
- NCT06545032
- Testing
- lumbar fusion
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Trauma
Surgical Stress Measured by Microdialysis
Paraspinal muscle damage is inevitable during conventional posterior lumbar fusion surgery. Minimal invasive surgery is postulated to result in less muscle damage and better outcome.
- Trial name
- NCT01495143
- Testing
- Posterolateral lumbar fusion surgery
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark
Degenerative Spine Diseases, Surgical Wound
Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and…
- Trial name
- NCT06427850
- Testing
- Tranexamic acid, Normal saline
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Thanawan Longsuwan
Lumbar Fusion Surgery
Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery
The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the lumbar fusion surgery.
- Trial name
- NCT04983966
- Testing
- Desflurane, Remimazolam
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Spinal Stenosis Lumbar, Disc Degeneration
Efficacy and Safety of Preemptive Intravenous Dexamethasone in MIS-TLIF
Researchers are considering Dexamethasone as preemptive medication before minimally invasive spine fusion surgery to minimize postoperative back pain with minimal side effects, aiming to enhance the effectiveness of surgery and…
- Conditions
- Spinal Stenosis Lumbar, Disc Degeneration, Disc Disease, Fusion of Spine
- Trial name
- MIS-TLIF (NCT06367855)
- Testing
- Dexamethasone, Normal saline
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Potsawat Surabotsopon
Degenerative Lumbar Spondylolisthesis
Degenerative Spondylolisthesis; Micro-decompression vs Decompression + Instrumented Fusion; Long Term Follow up
In many countries a majority of patients with degenerative spondylolisthesis are operated on with decompression plus instrumented fusion, but the scientific evidence for adding fusion is controversial.
- Trial name
- DS-registry (NCT03469791)
- Testing
- Surgical treatment of Degenerative Spondylolisthesis
- Where
- Norway
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Low Back Disorder
MMG vs. EMG for Cortical Breach Detection
The purpose of this study is to determine how well mechanomyography (MMG) and electromyography (EMG) prevent cortical bone breaches, or the pinching of a nerve from screw placement, in patients having lower back surgery requiring…
- Trial name
- NCT05352048
- Testing
- Triggered Electromyography, Mechanomyography
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Francis Farhadi
Pain, Postoperative
Erector Spinae Plane Block Analgesia for Lumbar Spine Fusion Surgery
The purpose of this study was to investigate the effect of a bilateral ultrasound guided erector spinae plane block on the pain scores and opoid utiliziation in fusion surgery of the lumbar spine.
- Trial name
- NCT04749095
- Testing
- Erector spinae plane block
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Benha University
Erector Spinae Block, Lumbar Fusion Surgeries
Adding Dexmedetomidine to Bupivacaine for Bilateral Erector Spinae Block
The aim of this study is to compare the analgesic effect of bilateral US-guided ESPB using bupivacaine alone versus bupivacaine and DEX in lumbar fusion surgeries.
- Conditions
- Erector Spinae Block, Lumbar Fusion Surgeries, Dexmedetomidine
- Trial name
- NCT06231979
- Testing
- Dexmedetomidine, Bupivacain, Normal saline
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Assiut University
Physical Capability Outcomes
Physical Capability Outcomes After Single-Level PD-L vs Single-Level ALIF: a Multi-Center Clinical Trial
The purpose of this study is to compare the physical capability outcomes of patients who undergo single-level ProDisc-L disc replacement with those of patients who undergo stand-alone, single-level anterior lumbar interbody…
- Trial name
- NCT01055574
- Where
- 6 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gundersen Lutheran Medical Foundation
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Effect of RECK in Posterior Spinal Fusion
"RECK" is a combination of local anesthesia medications, used for the purpose of pain control. RECK is an acronym which stands for Ropivacaine, Epinephrine, Clonidine, and Ketorolac.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
- Trial name
- NCT06447194
- Testing
- Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Hip Fractures, Anesthesia, Local
Shamrock - Ultrasound/MR Image Fusion Guided Lumbar Plexus Block
The main objective is to complete a double-blinded randomized controlled crossover trial of lumbar plexus block with the Shamrock technique guided by ultrasound (US)/magnetic resonance imaging (MRI) image fusion vs.
- Conditions
- Hip Fractures, Anesthesia, Local, Pain, Postoperative
- Trial name
- NCT02718976
- Testing
- Lidocaine-epinephrine added gadoterate meglumine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Degenerative Disc Disease, Spondylolisthesis, Lumbar Region
Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions
Spinal operations including lumbar fusions for degenerative disorders are becoming more prevalent as the population ages. Inadequate or excessive postoperative analgesia can result in medical comorbidities and prolonged hospital…
- Trial name
- NCT04112550
- Testing
- Methadone Hydrochloride, Oxycodone-Acetaminophen
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Degenerative Disc Disease Lumbar, Spinal Stenosis
Multimodal Analgesia Versus Routine Care Pain Management
Most patients undergoing surgery experience significant post-operative pain. Inadequate peri-operative pain management may decrease post-operative mobilization and increase length of hospitalization.
- Conditions
- Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
- Trial name
- MMA (NCT01861743)
- Testing
- Multimodal Analgesia, Patient controlled analgesia
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Blood Loss, Surgical
Effect of Equal Ratio Ventilation on Blood Loss During Posterior Lumbar Interbody Fusion Surgery
Ventilator mode change was associated with decrease in blood loss during posterior lumbar interbody fusion (PLIF) due to decrease in the peak inspiratory pressure (PIP).
- Trial name
- NCT03030963
- Testing
- Equal ratio ventilation(ERV), I:E Ratio "1:2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Lumbar Fusion
Wound Drain After Lumbar Fusion Surgery
Postoperative drain placement is often used following spine surgery. These drains are placed with the intention to decrease the incidence of postoperative hematoma and its associated complications including wound complications…
- Trial name
- NCT06536842
- Testing
- Postoperative Drain Placement, No Postoperative Drain Placement
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics