Clinical trials: Lumbar Herniated Disc
Stenosis, Herniated Nucleus Pulposus
Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion
Neural injury is a well-known complication following extreme lateral lumbar interbody fusion (XLIF). It has been found that up to 9.4% of patients will have either temporary or persistent neurologic deficit.
- Conditions
- Stenosis, Herniated Nucleus Pulposus, Degenerative Disc Disease, Spondylosis
- Trial name
- NCT03327272
- Testing
- Methylprednisolone, Saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Lumbar Disc Herniation
Effectiveness of PEMF in Patients With Chronic Radicular Pain Due to Lomber Disc Herniation
The aim of this study is to investigate the effectiveness of pulse magnetic field therapy on pain, functional status, and quality of life in patients with chronic radicular pain due to lumbar disc herniation.
- Trial name
- NCT04049812
- Testing
- PEMF, Hot pack, TENS
- Volunteers
- 50 people
- Sponsor
- Birkan Sonel Tur
Disc Herniation
Fear-Avoidance Beliefs and Physical Function in Patients With Lumbar Disc Herniation
Lumbar disc herniation is one of the most common causes of low back pain and is associated with substantial functional limitations and reduced quality of life, particularly among working-age individuals.
- Trial name
- FAB-LDH (NCT07674407)
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Istinye University
Lumbar Disc Prolapse With Radiculopathy
Safety Study of ARO Spinal System as an Adjunct to Lumbar Decompression
To evaluate the clinical safety and effectiveness of the ARO Spinal System and to assess preliminary cost/benefit analysis in patients undergoing decompression surgery for symptomatic lumbar disc herniations.
- Trial name
- NCT01970514
- Testing
- ARO Spinal System
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- ARO Medical
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Lumbar Disc Herniation, Lumbar Radiculopathy
Effects of SNAGS With and Without Pilates in Lumbar Disc Bulge Patients
The aim of this study is to compare the effects of Sustained Natural Apophyseal Glides with and without Pilates on pain, range of motion and disability in patients with lumbar Disc Bulge.
- Trial name
- NCT06076408
- Testing
- SNAGS with Pilates, SNAGS
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Vibration, Lumbar Disc Herniation
IASTM and Vibration Effects on Pain, Functionality, and Kinesiophobia in Lumbar Disc Herniation
The aim of this study is to investigate the effects of Instrument-Assisted Soft Tissue Mobilization and vibration massage therapy on pain, functionality, and kinesiophobia in individuals with lumbar disc herniation.
- Conditions
- Vibration, Lumbar Disc Herniation, Soft Tissue Mobilization
- Trial name
- NCT07293676
- Testing
- Exercise, IASTM, Percussion massage therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Degenerative Disc Disease, Spondylolisthesis
Clinical and Radiological Outcomes of Oblique Lateral Lumbar Interbody Fusion
This study is undertaken to evaluate the outcomes of Oblique Lateral Lumbar Interbody Fusion (OLLIF). Specifically, the study seeks to measure outcomes on radiological imaging, outcomes reported by the patients on standardized…
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Lumbar Disc Herniation
- Trial name
- NCT03726190
- Testing
- Oblique Lateral Lumbar Fusion
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Tristate Brain and Spine Institute
Lumbar Stenosis, Familial
Place of Ultrasound Guidance of Surgery Site in Surgery for Lumbar Canal Stenosis and Lumbar Disc Herniations
The identification of the operative site of lumbar ductal stenosis and lumbar disc herniation is classically done by radioscopy, thus inducing irradiation of the patient.
- Trial name
- NCT04124627
- Testing
- Ultrasound guidance in addition to radiographic guidance
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Medico-Chirurgicale et Obstetrique Cote d'Opale
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Application of 3D Printing Guide Plate in Endoscopic Spinal Surgery
Application of 3D printing guide plate in endoscopic spinal surgery
- Conditions
- Lumbar Disc Herniation, Lumbar Spinal Stenosis, Radicular Pain, Low Back Pain
- Trial name
- NCT05632835
- Testing
- 3D printing guide plate, Conventional guidance
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation
Effect of Feedback Health Education on Postoperative Rehabilitation of Patients With Lumbar Disc Herniation
Aims and Objective: A theoretical model based on guided postoperative rehabilitation with feedback was developed for patients with lumbar intervertebral disc protrusion to explore the effects of feedback-based health education.
- Trial name
- NCT04885140
- Testing
- Feedback-based health education, Routine health education
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tianjin Hospital
Lumbar Disc Herniation
Comparison of Cyriax Manipulation and Decompression in LDP
In this study, compare the effects of Cyriax manipulation and Decompression in patient with lumber disc prolapseThis research will provide an important addition to the evidence based treatment intervention in physical therapy in…
- Trial name
- NCT04653870
- Testing
- cyriax manipulation lumber, lumber decompression
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
Posterolateral Disc Herniation L4-L5-S1, Disk Herniated Lumbar
Ultrasound-guided Percutaneous Electrolysis Compared to Placebo Acupuncture in Posterolateral Lumbar Disc Herniation
Lumbar discopathies are among the most common medical concerns in Europe and Spain. Globally, around 2-3% of the population is affected by this condition, which manifests as tingling, burning, itching, muscle weakness, limb pain…
- Trial name
- NCT06569069
- Testing
- US guided PE
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Zaragoza
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Safety and Effectiveness Evaluation of Spinal Laminectomy Robot
The purpose of this clinical trial is to evaluate the effectiveness and safety of this spinal robot in assisting doctors to perform laminectomy in spinal surgery under the premise of ensuring the safety of the subjects and…
- Trial name
- NCT06593574
- Testing
- Robotic laminectomy, Traditional laminectomy
- Where
- 3 sites in China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation
Non-pharmacological Treatment vs Pharmacological Treatment for Non-acute Lumbar Disc Herniation
This is a randomized controlled study comparing non-pharmacological treatment to proactive pharmacological treatment for patient with non-acute lumbar disc herniation with moderate or higher levels of pain.
- Trial name
- NCT06024460
- Testing
- non-pharmacological treatment strategy, pharmacological treatment strategy
- Where
- 4 sites in South Korea
- Volunteers
- 200 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Disc Herniation, Annular Disc Tear
A Post Marketing Surveillance Study
This study is a prospective, multi-center study to monitor the early safety and performance of one iteration of the Barricaid Anular Closure Device (ACD) - 6mm anchor width, when used as an adjunct to limited discectomy.
- Conditions
- Lumbar Disc Herniation, Annular Disc Tear, Annular Tear of Lumbar Disc
- Trial name
- 6MM (NCT03366779)
- Testing
- 6mm annular closure device
- Where
- 2 sites in Belgium, Germany
- Volunteers
- 20 people
- Sponsor
- Intrinsic Therapeutics
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Lumbar Radiculopathy, Lumbar Disc Herniation
Treatment Response to TFESI and DRG Pulsed RF in Lumbar Spinal Stenosis and Disc Herniation
Lumbar radiculopathy caused by conditions such as lumbar disc herniation (LDH) and lumbar spinal stenosis (LSS) can lead to chronic pain and reduced quality of life.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis (LSS)
- Trial name
- NCT07509580
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University