Clinical trials: Lumbar Laminectomy
Lumbar Spine Disease
Efficacy of Motor Control Exercise Program After Lumbar Spinal Decompression Surgery
The study will be conducted with volunteer patients who have undergone lumbar decompression surgery and who are followed up by the Neurosurgery outpatient clinic of Fethiye State Hospital.
- Trial name
- NCT06014632
- Testing
- Rehabilitation, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Muğla Sıtkı Koçman University
Lumbar Spine Stenosis, Lumbar Spine Degeneration
OpalGenix- Personalized Postoperative Pain Management Following Lumbar Spinal Fusion and Decompression Surgery in Adults
The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research.
- Trial name
- NCT05452694
- Where
- 3 sites in United States
- Volunteers
- 235 people
- Sponsor
- OpalGenix, Inc
Spine Surgery, Reversal of Neuromuscular Blockade
Sugammadex vs Neostigmine/Glycopyrrolate on Urinary Retention After Spine Surgery
This is an active-comparator controlled study to evaluate the effect of sugammadex compared to neostigmine/glycopyrrolate for reversal of rocuronium on the incidence of urinary retention after subjects undergo elective ambulatory…
- Conditions
- Spine Surgery, Reversal of Neuromuscular Blockade, Urinary Retention Postoperative
- Trial name
- NCT05887375
- Testing
- Sugammadex, Neostigmine, Glycopyrrolate
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Missouri-Columbia
Spinal Stenosis
MIS-D Versus MIS-TLIF for the Treatment of Lumbar Spinal Stenosis
The purpose of this study is to evaluate the effectiveness of two minimal invasive spine surgery, minimally invasive spinal decompression (MIS-D) and minimally invasive spinal decompression and fusion (MIS-TLIF), for patients…
- Trial name
- NCT04318795
- Testing
- minimally invasive spinal decompression (MIS-D), minimally invasive spinal decompression and fusion (MIS-TLIF)
- Volunteers
- 80 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Low Back Pain
Effectiveness of Caudal Epidural Injections in Treatment of Chronic Low Back and Lower Extremity Pain
To demonstrate clinically significant improvements or lack thereof in the caudal epidural patients with our without steroids. To evaluate differences in outcomes in patients receiving steroids compared to those patients…
- Trial name
- NCT00370799
- Testing
- Caudal epidural injection, Caudal Epidural Injection with generic Celestone, Caudal Epidural Injection with Celestone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Pain Management Center of Paducah
Lumbar Disc Herniation
Remission of Lumbar Disc Herniation by Physiotherapy
This study was conducted with the aim of determining whether or not Non surgical spinal decompression therapy was effective in remission of herniation, decreasing pain and improving functional status.
- Trial name
- NCT02699164
- Testing
- DRX 9000, Axiom Worldwide, Tampa, Florida, physiotherapy, spinal stabilization exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Low Back Pain, Lumbar Disc Disease
Efficacy of Mechanical Traction and Spinal Decompression Treatments in Patients With Low Back Pain
Motorized traction and non-surgical spinal decompression treatments are relatively new treatments for which there is insufficient evidence in the literature.
- Conditions
- Low Back Pain, Lumbar Disc Disease, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT05617924
- Testing
- Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Afyonkarahisar Health Sciences University
Drain Tube Influence the Postoperative Epidural Haematoma
Does a Drain Tube Influence the Postoperative Epidural Haematoma for Lumbar Biportal Endoscopic Surgery?
The purpose of this study was to evaluate if wound drains could influence postoperative spinal epidural hematoma (POSEH) in biportal endoscopic spinal surgery (BESS) procedures for decompression of lumbar spinal stenosis.
- Trial name
- NCT06290791
- Testing
- two level lumbar decompression with BESS procedure received one drain., two level lumbar decompression with BESS procedure received two drain.
- Where
- China
- Volunteers
- 89 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Post-Operative Pain, Lumbar Laminectomy
HTX-011 in Spinal Surgery
This is a Phase 2, multicenter study in subjects undergoing an open lumbar decompression surgery.
- Trial name
- NCT04911062
- Testing
- Bupivacaine HCI without epinephrine, HTX-011, Luer Lock Applicator
- Where
- 12 sites in United States
- Volunteers
- 32 people
- Sponsor
- Heron Therapeutics
Laminectomy
Esmolol Infusion During Laminectomy: Effect on Quality of Recovery
The purpose of this study is to evaluate the effects of esmolol, a drug which is commonly administered during surgery to help control blood pressure and heart rate, on postoperative pain levels and requirements for pain…
- Trial name
- NCT01179113
- Testing
- Esmolol, Saline
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Cedars-Sinai Medical Center
Spinal Stenosis, Lumbar Region With Neurogenic Claudication
Assessing Superion Clinical Endpoints vs. Decompression
PURPOSE: The primary purpose of this study is to demonstrate that the Composite Clinical Success of the study group receiving the Superion® IDS is not inferior to the success rate observed in the study group treated by direct…
- Trial name
- ASCEND (NCT03048955)
- Testing
- Superion® IDS, Direct decompression Surgery
- Where
- 5 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VertiFlex, Incorporated
Spinal Stenosis, Spinal Cord Compression
Comparative Effectiveness of Microdecompression and Laminectomy for Central Lumbar Spinal Stenosis
Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis.
- Trial name
- NCT02006901
- Testing
- microdecompression, laminectomy
- Where
- Norway
- Volunteers
- 721 people
- Sponsor
- St. Olavs Hospital
Low Back Pain, Herniation, Disc
Non-surgical Spinal Decompression Therapy and Outcomes
This project will determine the clinical utility of non-surgical spine decompression for chronic low back pain (LBP). LBP is one of the highest incidence medical conditions that contributes to disability, decreased activities of…
- Conditions
- Low Back Pain, Herniation, Disc, Sciatic Radiculopathy, Intervertebral Disc Stenosis of Neural Canal
- Trial name
- RESTORE (NCT06525896)
- Testing
- NSSD
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of South Florida
Lumbar Spinal Stenosis
Effects of X-STOP® Versus Laminectomy Study
To determine if the effectiveness of the X-STOP® implant is equivalent (non-inferior) to that of conventional laminectomy in patients with lumbar spinal stenosis as measured by the Zurich Claudication Questionnaire.
- Trial name
- EXELS (NCT00558129)
- Testing
- X-STOP®, Laminectomy
- Sponsor
- Medtronic Spine LLC
Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis
Clinical Evaluation of Orion Lamina Cover in Patients Undergoing Lumbar Laminectomy With Instrumented Fusion
Laminectomy with internal fixation and osseofusion is a common surgery for treating degenerative spinal diseases. It removes excessive bone spurs and removes the lamina for decompression to relieve nerve compression, and then…
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Spondylolisthesis, Spinal Stenosis, Scoliosis
- Trial name
- NCT06532968
- Testing
- ORION spinal lamina cover
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Orion Biotech Inc.
Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome
Persistent Post-Lumbar Surgery Pain Syndrome (PSPS) Type II is a Common Condition Encountered in Pain Units, With Limited Available Therapeutic Options. Epidural Pulsed Radiofrequency (PRF) Administered Via Catheter Has Demonstrated Greater Efficacy Compared to the Transforaminal Approach. This Rand
This study is for people who continue to have low back pain after spinal surgery, a condition called persistent spinal pain syndrome type II. Current treatments, such as epidural injections, often provide only limited relief.
- Conditions
- Persistent Spinal Pain Syndrome Type II, Failed Back Surgery Syndrome, Chronic Low Back Pain, Post-Laminectomy Syndrome
- Trial name
- EPIPUL (NCT07156513)
- Testing
- Epidural Pulsed Radiofrequency, Betamethasone (Epidural Corticosteroid Injection)
- Where
- 4 sites in Spain
- Volunteers
- 131 people
- Sponsor
- Puerta de Hierro University Hospital
Syndrome, Manganese Neurotoxicity
Effects of Thoracolumbar Stabilization Versus Spinal Decompression Exercises on Maigne's Syndrome
The study was conducted to compare the effect of thoracolumbar stabilization exercises versus spinal decompression exercises on pain, range of motion, disability and posture in patients with maigne's syndrome.
- Trial name
- NCT07426900
- Testing
- Lumbothoracic stabilization exercises, Spinal decompression exercises, Standardized physical therapy treatment
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Spinal Stenosis, Spondylolisthesis
Greenwich Lumbar Stenosis SLIP Study
The purpose of the study is to determine the proper use of lower back screws and rods (instrumentation) and bony fusion in subjects with one level of degenerative spinal narrowing (stenosis) compressing nerves to the legs with…
- Trial name
- SLIP (NCT00109213)
- Testing
- Lumbar Laminectomy with Instrumented Pedicle Screw Fusion, Lumbar Laminectomy
- Where
- 5 sites in United States
- Volunteers
- 66 people
- Sponsor
- Greenwich Hospital
Radiculopathy Lumbar
Spinal Decompression Therapy in Radicular Chronic Low Back Pain
The study design was randomized control trial and sampling technique was lottery method. After inclusion and exclusion criteria, sample populations were divided into experimental (group A) and control group (group B).
- Trial name
- NCT04701879
- Testing
- Spine decompression with core stability exercises, Spine decompression
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Laminectomy, Postperative Pain Management
Dexamethasone as ESPB Adjuvant in Lumbar Laminectomy
Laminectomy is a routine procedure for patients with lumbar spinal stenosis, offering significant benefits such as reduced low back pain, alleviation of radiculopathy, and improved motor strength 1 23.
- Conditions
- Laminectomy, Postperative Pain Management, Prostaglandin E2, Lumbal Disc Herniation
- Trial name
- NCT07429708
- Testing
- Bilateral ESPB: Ropivacaine 0.375% + Dexamethasone 5mg, Bilateral ESPB: Ropivacaine 0.375%
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Udayana University