Clinical trials: Lumbar Surgery
Lumbosacral Spinal Stenosis
Irrigation Endoscopic Decompressive Laminotomy
The classic laminectomy for surgical treatment of spinal stenosis has considerable morbidity .This is further magnified by the disease being more common in elderly with associated medical comorbidities and being usually global…
- Trial name
- NCT01991912
- Testing
- open lumbar decompression
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pressure Injury
Preventing Pressure Injuries in Patients Undergoing Lumbar Spine Surgery
Background：Pressure injuries (PI) are one of the common comorbidities in surgery, meaning PI that occurs immediately after surgery or within hours to 3 days after surgery. The incidence of PI in spine surgery is about 5% ~ 66%.
- Trial name
- NCT06015139
- Testing
- cotton roll-coated viscoelastic polymer pads, viscoelastic polymer pads
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Central Taiwan University of Science and Technology
Degenerative Spine Diseases, Surgical Wound
Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)
The randomized controlled study which compare the efficacy outcomes (reducing blood loss and drainage output in patients) in patients undergoing single-level minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) and…
- Trial name
- NCT06427850
- Testing
- Tranexamic acid, Normal saline
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Thanawan Longsuwan
Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF)
Effect of Addition of Dexmedetomidine During Ultrasound Guided Bilateral Single Shot Erector Spinae Plane Block in Patients Undergoing Posterior Lumbar Interbody Fusion Under General Anesthesia
Posterior lumbar interbody fusion (PLIF) is the management of choice in double level lumbar (L) spondylolisthesis (L3-L5) after ineffective conservative treatment.
- Conditions
- Double Level Lumbar Spondylolisthesis (L3-L5), Posterior Lumbar Interbody Fusion (PLIF), Lumbar Fixation Surgery
- Trial name
- NCT03746418
- Testing
- Ultrasound Guided Bilateral single shot Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Lumbar Disc Herniation
Lidocaine Versus Esmolol for Optimizing Surgical Field Visibility
Intra-operative blood loss is an important attribution and predictor of the lumbar spine surgery and patient outcome. Stripping the muscle off bone makes more exposed bleeding spine surface is one of causes for blood loss during…
- Trial name
- NCT04260685
- Testing
- Lidocaine, Esmolol
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Lumbar Fusion, Lumbar Spinal Fusion Surgery
Clinical and Biomechanics Research in Core Muscles After Lumbar Fusion Surgery
Lumbar fusion has been widely used for spinal disorders when conservative treatment has failed. However, a number of studies have reported that the rate of re-operation is high for lumbar fusion surgery.
- Trial name
- NCT01703338
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lumbar Fusion Surgery
Comparison of Postoperative QoR-15 Scores Between Desflurane and Remimazolam in Lumbar Fusion Surgery
The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the lumbar fusion surgery.
- Trial name
- NCT04983966
- Testing
- Desflurane, Remimazolam
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Lumbar Disc Disease
NOCISCAN-Lumbar Spine (LS) Clinical Evaluation Study
A prospective, double blinded, multi-center study to assess the validity and clinical utility of the pre-operative NOCISCAN-LS software in the identification of painful lumbar discs, and the correlation with improved surgical…
- Trial name
- NCT04015791
- Testing
- NOCISCAN-LS Disc MR Spectroscopy
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Nocimed, LLC
Disc Herniation
The Effect of White Noise in Patients Undergoing Lumbar Disc Herniation Surgery
The aim of this clinical trial is to determine the effectiveness of listening to white noise on the sleep quality, comfort level, satisfaction level of patients after lumbar disc herniation surgery.
- Trial name
- NCT05687305
- Testing
- White Noise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Spine Disease, Spinal Deformity
The Effect of Telephone Education on Fear of Movement and Quality of Life in Patients With Lumbar Disc Herniation Surgery.
The aim is to quantify the fear of movement and quality of life of telephone education on lumbar disc herniation surgery.
- Trial name
- NCT06190873
- Testing
- post-discharge rehabilitation training
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Post-operative, Analgesia
Erectae Spinae Block Versus Intrathecal Morphine for Postoperative Analgesis in Lumbar Surgeries
The study design will be double blinded retrospective controlled comparative study. The patients will be included in the study shoud be in the following category: American Society of Anesthesiologists (ASA) physical status I, II…
- Trial name
- NCT05123092
- Testing
- Ultrasound guided lumbar erectae spinae block, Intrathecal Morphine injection
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Dexmedetomidine VS Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
Evaluation of the Analgesic Effect of Dexmedetomidine Versus Fentanyl as Adjuvants to Epidural Bupivacaine in Patients Undergoing Lumbar Spine Surgeries
To determine if the epidural route provide an acceptable analgesia in spine surgeries and avoided the need for excessive IV analgesics.
- Trial name
- NCT03463083
- Testing
- Dexmedetomidine, Bupivacaine, Fentanyl
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Morphine
Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal Surgery
The effect of epidural low-dose morphine-soaked microfibrillar collagen sponge in postoperative pain control after posterior lumbar spinal surgery: a randomized, double-blind, placebo-controlled study
- Trial name
- NCT02067338
- Testing
- 1 mg morphine soak in epidural oxidized cellulose, normal saline
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Postoperative Pain
Efficiency of Thoracolumbar Interfascial Plane Block in Lumbar Disk Surgery
Objectives:Lomber disc hernia is one of the most common diseases in Turkey. The prevalence in various studies is between 60-80% and incidence is between 1-3% for the entire population,Goal of TLIP is to provide a same impact in…
- Trial name
- NCT03180099
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Erzurum Palandöken State Hospital
Opioid Consumption, Postoperative, ESPB
Evaluation of the Postoperative Efficacy of Bilateral Lumbar Erector Spinae Plane Block (ESPB) in Patients Undergoing Lumbar Disc Herniation Repair Surgery
This prospective observational study aims to evaluate the efficacy of bilateral lumbar erector spinae plane (ESP) block in providing effective postoperative analgesia and its potential impact on early mobilization and length of…
- Conditions
- Opioid Consumption, Postoperative, ESPB, Postoperative Pain, Plane Blocks
- Trial name
- NCT07403734
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
To Compare Efficacy of Dexmedetomidine in Bilateral Quadratus Lumborum vs Lumbar Epidural Blocks on Analgesia After Major Lower Abdominal Surgery
Clinical Efficacy and Safety of Dexmedetomidine as an Adjuvant in Quadratus Lumborum Versus Epidural Block in Postoperative Lower Abdominal Cancer Surgeries
Clinical efficacy and safety of dexmedetomidine as an adjuvant in quadratus lumborum versus epidural block in postoperative patients
- Trial name
- NCT06130670
- Testing
- nerve block
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
Isthmic Spondylolisthesis
Anterior vs Posterior Surgery for Lumbar Isthmic Spondylolisthesis
Currently there is no consensus on the best surgical treatment of patients with symptomatic isthmic spondylolisthesis (IS). Clinical equipoise exists amongst experienced clinicians on the various surgical techniques available.
- Trial name
- NCT05701046
- Testing
- Interbody fusion surgery
- Where
- Canada
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Surgical Wound, Herniation
Efficacy of a Full-Thickness Placental Allograft in Lumbar Microdiscectomy
To evaluate the efficacy of full thickness placental allograft use in Microdiscectomy application. To evaluate post-microdiscectomy reherniation rate in patients treated with full-thickness placental allografts.
- Trial name
- NCT03536013
- Testing
- Other: Full-thickness placental allograft
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- StimLabs
Physical Capability Outcomes
Physical Capability Outcomes After Single-Level PD-L vs Single-Level ALIF: a Multi-Center Clinical Trial
The purpose of this study is to compare the physical capability outcomes of patients who undergo single-level ProDisc-L disc replacement with those of patients who undergo stand-alone, single-level anterior lumbar interbody…
- Trial name
- NCT01055574
- Where
- 6 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gundersen Lutheran Medical Foundation