Clinical trials: Lumbar Surgery
Sufentanil, Morphine
Comparison of the Analgesic Effect of Oliceridine Versus Morphine or Sufentanil for Postoperative Analgesia in Lumbar Surgeries: a Randomized Control Trial
Objective: This study aimed to compare the efficacy and safety of oliceridine versus morphine and sufentanil for postoperative analgesia following elective lumbar spine surgery.
- Conditions
- Sufentanil, Morphine, Validity, Safety
- Trial name
- NCT06990893
- Testing
- Oliceridine, Morphine, Sufentanil
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anqing Municipal Hospital
Cervical Spinal Stenosis, Thoracic Spinal Stenosis
The Effect of Oxytocin Nasal Spray on Preventing Postoperative Delirium in Elderly Patients Undergoing Orthopedic Surgery
Postoperative delirium is a delirium that occurs within 7 days after surgery or before hospital discharge. It has been shown that combined POD can increase the incidence of postoperative pulmonary infections, deep vein thrombosis…
- Conditions
- Cervical Spinal Stenosis, Thoracic Spinal Stenosis, Lumbar Spinal Stenosis, Rotator Cuff Injury
- Trial name
- NCT06945926
- Testing
- oxytocin nasal spray
- Where
- China
- Volunteers
- 227 people
- Sponsor
- Zhejiang University
Osteoporosis, Fusion of Spine, Lumbar Region
Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery
This project aims to investigate any difference of insertional torque strength for osteoporotic patients with preoperative 1-month teriparatide injections versus those without.
- Trial name
- NCT03770338
- Testing
- Teriparatide
- Where
- 3 sites in Hong Kong
- Volunteers
- 192 people
- Sponsor
- The University of Hong Kong
Spinal Stenosis Lumbar, Surgical Site Infection
Efficacy of ActiveMatrix on Spinal SSI Rate
This clinical trial seeks to provide high level of evidence on the efficacy of ActiveMatrix primarily on spinal surgical site infection rate.
- Conditions
- Spinal Stenosis Lumbar, Surgical Site Infection, Back Pain Lower Back Chronic
- Trial name
- NCT05297513
- Testing
- ActiveMatrix
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Paraspinal Muscles, Degenerative Lumbar Diseases
The Impact of Paraspinal Muscle Atrophy in Spine Surgeries
The goal of this observational study is to learn about the role of pre-operative paraspinal muscle atrophy in outcomes of lumbar spine fusion surgeries in patients with degenerative lumbar spine diseases.
- Trial name
- NCT07002918
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Assiut University
Lumbar Spinal Stenosis
Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)
BACKGROUND: Lumbar spinal stenosis - known by patients as "arthritis of the spine" - is a condition that is very common; found in about 30% of older adults.
- Trial name
- NCT01943435
- Testing
- NSAIDs; adjunctive analgesics; adjunctive anti-depressants, Lumbar epidural injection, Joint Mobilizations (spine, sacroiliac, hip)
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Michael Schneider, DC, PhD
Scoliosis, Kyphosis
Comparison of Actifuse ABX and Local Bone in Spinal Surgery
This study is being done to compare people who had a standard of care spinal fusion using part of their local bone graft (a small amount of bone from the region of the spine where the fusion is occurring) to correct an adult…
- Conditions
- Scoliosis, Kyphosis, Lordosis
- Trial name
- NCT01852747
- Testing
- Multilevel Spinal fusion with Actifuse ABX®
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Ohio State University
Lumbar Disc Herniation, Lumbar Radiculopathy
Selective Nerve Root Block Versus Sham to Reduce Surgery for Lumbar Disc Herniation
The SELDISC trial will investigate whether a selective nerve root block can reduce the need for surgery in adults with a herniated disc in the lower back.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Lumbar Disc Herniation With Radiculopathy
- Trial name
- SELDISC (NCT07895589)
- Testing
- Selective Nerve Root Block
- Where
- 2 sites in Sweden
- Volunteers
- 262 people
- Sponsor
- Karolinska Institutet
Low Back Pain, Lumbar Spine Injury
Second Opinion in Spinal Surgery Indications: Cost-Effectiveness Evaluation
Low back pain is a common symptom, which often affects the adult population. Studies show that over the past two decades, costs related to spinal surgery have increased significantly, leading to speculation about what would be…
- Trial name
- NCT03082248
- Testing
- Physical Therapy, Spinal Surgery
- Where
- Brazil
- Volunteers
- 190 people
- Sponsor
- Hospital Israelita Albert Einstein
Spinal Instability
CLUBE (UBE Stability / Dynamic Radio)
Degenerative pathologies of the spine affect a large proportion of the increasingly ageing population, and are a major public health issue.
- Trial name
- NCT06904326
- Testing
- Postoperative dynamic radiography
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Clinique Saint Jean, France
Lumbar; Injury
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Treatment in Spinal Surgery
Spinal surgeries are generally associated with intense pain in the postoperative period, especially for the initial few days. The aim of this study is to examine the effect of intraoperative intravenous acetaminophen in spine…
- Trial name
- NCT05764707
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Degenerative Lumbar Spondylolisthesis
Long-term Reoperations After Lumbar Spinal Stenosis Surgery
Severe and persisting pain and disability due to a degenerative narrowing of the spinal canal, lumbar spinal stenosis, can be operated with a simple surgical decompression.
- Trial name
- NCT06407063
- Testing
- Micro-decompression alone, Decompression and instrumented fusion
- Where
- Norway
- Volunteers
- 794 people
- Sponsor
- University Hospital of North Norway
Thoracolumbar Burst Fracture
Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment
Thoracolumbar (TL) burst fractures in neurologically intact patients account for approximately 45% of all TL spine injuries. Despite being common fractures, there is significant variability in treatment recommendations…
- Trial name
- NCT02827214
- Where
- 14 sites in United States, Australia and 8 more
- Volunteers
- 213 people
- Sponsor
- AO Innovation Translation Center
Postoperative Cognitive Dysfunction, NEURON SPECIFIC ENOLASE
EFFECT OF ANESTHESİA TECHNIQUES ON POSTOPERATİVE COGNİTİVE DYSFUNCTION FOR MMSE AND NSE LEVEL
The aim of this study is to compare the effects of total intravenous anesthesia and inhalation anesthesia methods on postoperative cognitive dysfunction according to Mini Mental State Examination scores and Neuron Specific…
- Conditions
- Postoperative Cognitive Dysfunction, NEURON SPECIFIC ENOLASE, MINI MENTAL STATE EXAMINATION TEST
- Trial name
- NCT04279132
- Testing
- POSTOPERATIVE COGNITIVE DYSFUNCTION
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Erzincan University
Failed Back Surgery Syndrome
A Post Market Study on DRG Stimulation in FBSS (SYMPATHY)
The purpose of this Post Market Observational Study is to monitor the effect of the Axium® SCS System in the management of chronic pain following surgical lumbar discectomy in subjects whom are routinely scheduled for treatment…
- Trial name
- NCT02634398
- Where
- Switzerland
- Sponsor
- Abbott Medical Devices
Lower Limb Surgery
Comparison of Two Position for Ultrasound Guided Lumbar Plexus and Sciatic Nerve Block
In the present study, the investigators will test the effect of two position on posterior lumbar plexus and subgluteal or sub-greater trochanter sciatic nerve block.
- Trial name
- NCT00988234
- Testing
- SGPP, SGTPP, SGLP
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Lumbar Disc Herniation
The Diagnostic and Prognostic Value of Two Quantitative Clinical Tests in Patients With Lumbar Disc Herniation
This study will investigate whether two clinical tests can be used to diagnose and predict the outcome in patients with lumbar disc herniation undergoing surgery and non-surgery treatment.
- Conditions
- Pain, Lumbar Disc Herniation, Back Pain, Spinal Diseases
- Trial name
- NCT03832036
- Testing
- Paraspinal Mapping and Quantitative Sensory Pain Test
- Where
- Denmark
- Volunteers
- 102 people
- Sponsor
- Spine Centre of Southern Denmark
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Surgery
QL vs LP Blocks for Analgesia Following THA
Purpose: Evaluate difference in postoperative opioid consumption when subjects receive a quadratus lumborum (QL) or lumbar plexus (LP) block preoperatively for total hip arthroplasty (THA).
- Trial name
- NCT04402437
- Testing
- LP Block, QL Block
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina