Clinical trials: Lung Cancer Symptoms
Lung Cancer (Diagnosis)
Serum Exosomal Long Noncoding RNAs as Potential Biomarkers for Lung Cancer Diagnosis
The study is to investigate the sensitivity and specificity of serum exosome noncoding RNA as a biomarker for the diagnosis of lung cancer
- Trial name
- NCT03830619
- Testing
- collect samples
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Smoking History, Current Smoker
Increasing Lung Cancer Screening Among Emergency Department Patients - LCS R01
This randomized clinical trial evaluates the effectiveness of text messaging and facilitated referral strategies to increase lung cancer screening uptake among emergency department patients who meet lung cancer screening…
- Conditions
- Smoking History, Current Smoker, Lung Cancer Screening
- Trial name
- NCT07566221
- Testing
- Basic Referral, Facilitated Referral, Text Messaging
- Volunteers
- 1,036 people
- Sponsor
- University of Rochester
Asthma (Diagnosis)
Longitudinal Phenotyping and Endotyping Study in Adult Patients With Mild, Moderate, or Severe Asthma
Background and study aims: The purpose of this research registry is to understand how asthma varies from person to person and monitor changes that may occur over time.
- Trial name
- MAPLE-UK (NCT07189806)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Hvivo
Sarcopenia, Non Small Cell Lung Cancer
Prognostic Value of Sarcopenia and Nutritional Status in Early-stage Non-small Cell Lung Cancer
Growing evidence has confirmed that the prognosis of lung cancer is not only related to the stage of disease, but also to the physiological and psychological situation of the patients.
- Conditions
- Sarcopenia, Non Small Cell Lung Cancer, Malnutrition
- Trial name
- NCT05212285
- Testing
- Inbody 570, JAMAR Dynamometer, CT scan
- Where
- China
- Volunteers
- 469 people
- Sponsor
- Fudan University
Multiple Myeloma
A Safety and Efficacy Study of Revlimid® 5 mg Capsules in Patients With Relapsed or Refractory Multiple Myeloma Who Have Received Long-term Treatment With it Under the Actual Condition of Use
To understand the safety and efficacy of Revlimid® 5 mg Capsules (hereinafter referred to as Revlimid) in patients with "relapsed or refractory multiple myeloma" (hereinafter referred to as "relapsed or refractory MM") who have…
- Trial name
- NCT02922543
- Where
- Japan
- Volunteers
- 361 people
- Sponsor
- Celgene
Lung Cancer, Head and Neck Cancer
Comparing Palliative Radiotherapy With or Without Carboplatin
The study population has locally advanced or metastatic bronchial or head and neck cancer. This study assesses the value of concomitant chemo/radiotherapy with carboplatin daily during metastatic radiotherapy versus radiotherapy…
- Conditions
- Lung Cancer, Head and Neck Cancer, Metastatic Cancer
- Trial name
- METAXIOM (NCT03637335)
- Testing
- irradiation + carboplatin
- Where
- 2 sites in France
- Volunteers
- 26 people
- Sponsor
- Institut Cancerologie de l'Ouest
Lung Cancer, Nonsmall Cell
A Radiomic Model for Risk of Local Recurrence and DFS for T3 and T4 Non-small Cell Lung Cancer
The investigators retrospectively collected the participants with T3 and T4, N0-2, M0 NSCLC patients resected between January 2013 to December 2021 for training and internal validation.
- Trial name
- NCT06405815
- Testing
- tumor and peritumor radiomic feature
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jinling Hospital, China
Lung Neoplasms, Diagnosis
Benefit of Cone-beam CT and Robotic-Assisted Bronchoscopy During Bronchoscopy
This randomized controlled trial evaluates the integration of cone-beam computed tomography (CBCT) and robotic-assisted bronchoscopy (RAB) for diagnosing pulmonary lesions, hypothesizing improved diagnostic yield compared to…
- Conditions
- Lung Neoplasms, Diagnosis, Lung Cancer
- Trial name
- NCT06489678
- Testing
- Robotic Assisted Bronchoscopy
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University of Zurich
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in Canada
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While short-term breathing problems caused by smoke are well known, there is limited knowledge on how repeated…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Lung Cancer
- Trial name
- LoF (NCT07536178)
- Testing
- Woodsmoke (Lodgepole Pine) exposure, Filtered air exposure
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Lung Cancer, Non-small Cell Lung Cancer
Oncology Research Information Exchange Network (ORIEN) Lung Cancer Study
The Moffitt Cancer Center and PatientsLikeMe.com (PLM), an online patient community, are working together to better understand the patient's entire lung cancer experience, both inside and outside the doctor's office.
- Trial name
- ORIEN (NCT02803333)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Non-Small Cell Lung Cancer (NSCLC, Locally Advanced or Metastatic, Second-line
The Study Of Andamertinib Plus Anlotinib In Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
This study is a single arm study to access the anti-tumor efficacy and safety of Andamertinib plus Anlotinib in patients with locally advanced or metastatic non-small cell lung cancer previously treated with third-generation…
- Trial name
- NCT07780578
- Testing
- Andamertinib, Anlotinib
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Fudan University
Cancer
Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00499733
- Testing
- cyclophosphamide, Cryoablation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Chemotherapy-induced Nausea and Vomiting, Lung Cancer
Olanzapine for the Prevention and Treatment of Nausea and Vomiting Induced by Chemotherapy of Lung Cancer
Chemotherapy induced nausea and vomiting (CINV) is a common adverse effect in treatment of cancer, which influences the quality of life and adherence to treatment of patients and leads to dehydration, malnutrition and even death.
- Trial name
- NCT03571126
- Testing
- Olanzapine
- Where
- 2 sites in China
- Volunteers
- 156 people
- Sponsor
- Zunyi Medical College
Solid Tumor, Adult, Non-small Cell Lung Cancer
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with BRAF/NRAS-mutated advanced or metastatic solid tumors.
- Conditions
- Solid Tumor, Adult, Non-small Cell Lung Cancer, Melanoma
- Trial name
- NCT04913285
- Testing
- KIN-2787, KIN-2787 and binimetinib
- Where
- 48 sites in United States, Australia and 5 more
- Volunteers
- 400 people
- Sponsor
- Pierre Fabre Medicament
Lung Cancer
Coagulation Profile in Patients Undergoing Video Assisted Thorascopic Surgery (VATS) for Lung Cancer
The purpose of the study is: To estimate patients with lung cancers who will undergo surgery total haemostatic / thrombotic capacity pre, per-and postoperatively.
- Trial name
- COPPVATS (NCT01741506)
- Testing
- Dalteparin (Fragmin®)
- Where
- 3 sites in Denmark
- Volunteers
- 116 people
- Sponsor
- Thomas Decker Christensen
Traumatic Brain Injury
A Clinical Trial to Determine the Safety and Efficacy of Hope Biosciences Autologous Mesenchymal Stem Cell Therapy for the Treatment of Traumatic Brain Injury and Hypoxic-Ischemic Encephalopathy
This study aims to determine the safety of HB-adMSC infusion and treatment effects of HB-adMSC infusion on brain structure, neurocognitive/functional outcomes, and neuroinflammation after subacute and chronic neurological injury…
- Trial name
- NCT04063215
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hope Biosciences LLC
Smoke Inhalation, Exposure, Inhalation
Lung Cancer Screening CT for Firefighters
Firefighters are at increased risk for cancer due to exposure to carcinogenic substances. Current lung cancer screening guidelines are predominantly based on smoking history and do not take into account high risk occupational…
- Conditions
- Smoke Inhalation, Exposure, Inhalation, Exposure to Pollution, Exposure Occupational
- Trial name
- NCT06836414
- Testing
- Low-dose Computerized tomography (CT) of Chest, Questionnaires, Medical History
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Oligometastases
SABR-SCAN Trial for Pulmonary Oligometastases
Rationale: SABR (Stereotactic ablative radiotherapy) is one of the standard treatment options besides surgical resection for limited lung metastases (oligometastases) from colorectal cancer.
- Trial name
- SABR-SCAN (NCT02414334)
- Testing
- Stereotactic Ablative Radiotherapy (SABR)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
Brain Metastases, Nsclc
The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases?
Patients suffering from malignancies in advanced stages often develop brain metastases, which limit both the life span and the quality of life.
- Trial name
- CyberChallenge (NCT05378633)
- Testing
- SRS, Whole Brain Radiotherapy
- Where
- Germany
- Volunteers
- 190 people
- Sponsor
- University Hospital Heidelberg
Chronic Myeloid Leukemia
Pulmonary Vasculopathy Under Second-line Therapy of Chronic Myeloid Leukemia
Chronic myelogenous leukemia (CML) is a chronic myeloproliferative disorder characterized by a translocation between chromosome 9 and 22, leading to a pathogenic tyrosine kinase signal transduction protein.
- Trial name
- NCT01805843
- Testing
- Echo, exercise echo, and if indicated, right heart catheter
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Graz
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