Clinical trials: Lung Collapse
Postoperative Atelectasis
Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound
Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical…
- Trial name
- LUS-ATELEC (NCT07320092)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Lung Collapse, One-Lung Ventilation
Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
Lung isolation technique and one-lung ventilation (OLV) are the mainstays of thoracic anesthesia. Two principal lung isolation techniques are mainly use by clinicians, the double lumen tubes (DLT) and the bronchial blockers (BB).
- Conditions
- Lung Collapse, One-Lung Ventilation, Thoracic Surgery, Video-Assisted
- Trial name
- PLC-OLV (NCT02919267)
- Testing
- Double lumen tube, Bronchial blocker
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
Cytokine Storm, COVID-19
Cytokine Storm Among Bangladeshi Patients With COVID-19
COVID -19, first reported in Wuhan, China, strikes the world hard as a pandemic by spreading up to 213 countries. Bangladesh is also facing its havoc with the death of 3000 among 229,185 cases at its 141st day.
- Trial name
- NCT04598334
- Where
- Bangladesh
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Respiratory Distress, Newborn
Effectiveness of HVNI in Preterm Infants With Moderate Respiratory Distress
Neonatal respiratory distress is a common problem in preterm infants. The application of CPAP is widely used in neonatal units as a primary mode of respiratory support for respiratory distress.
- Trial name
- NCT06436222
- Testing
- HVNI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Multi-organ Failure After Severe Trauma
Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma
Severe trauma remains the leading cause of death in people under 50, and is associated with high morbidity, including severe disability, with a substantial socio-economic impact.
- Trial name
- METAKIT (NCT06167512)
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cytokine Storm
The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People
The effect of Weekly 50,000 IU vitamin D3 supplements on the serum levels of selected cytokines involved in cytokine storm of Covid-19; A randomized clinical trial in the Covid-19 uninfected people with vitamin D deficiency.
- Trial name
- NCT04476745
- Testing
- Vitamin D3
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Postoperative Complications, Cancer
Predictive Value of Ariscat Index In The Development of Pulmonary Complication After Major Abdominal Cancer Surgery
The term postoperative pulmonary complication is the development of any complications affecting the respiratory system after anesthetic and surgery procedures.
- Conditions
- Postoperative Complications, Cancer, Pulmonary Complication, Atelectasis
- Trial name
- NCT04663958
- Testing
- Detection / Screening
- Where
- Turkey (Türkiye)
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Lung Ultrasound, Atelectasis
Surgical Positions and Postoperative Atelectasis: A Lung Ultrasound Study
The aim of this study is to prospectively evaluate the effect of surgical position on the development of postoperative atelectasis in patients undergoing surgery in supine, prone, lateral decubitus, and lithotomy positions using…
- Trial name
- NCT07654153
- Testing
- lung ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Decay, Dental, Missing Teeth
Relationship Between Oral Findings and Salivary Factors in Sars-Cov-2 Patients
Two hundred individuals will be formed according to the study and control groups: Group-1: coronavirus 2 (Covid-19) (+) patients (n=100) and Group-2: Healthy individuals (in which the volunteers will be included due to group-1)…
- Conditions
- Decay, Dental, Missing Teeth, COVID-19, Cytokine Storm
- Trial name
- NCT05476848
- Testing
- ELISA test for Cytokines
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Ege University
Atelectasis, Cesarean Section
The Effect of Oxygen Therapy on Atelectasis
In pregnancy, cephalal shift of the diaphragm caused by the enlarged uterus reduces the functional residual capacity and may increase the closure volume and predispose the pregnant woman to airway closure, leading to atelectasis.
- Conditions
- Atelectasis, Cesarean Section, Hypotension
- Trial name
- NCT05509764
- Testing
- lung ultrasound score
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Obesity, Pulmonary Atelectasis
Effects of PEEP on Heart and Lungs in Obese Subjects
Aim of this study is to better understand pathophysiology of the alteration of respiratory mechanics and cardiovascular function in obese volunteer subjects.
- Conditions
- Obesity, Pulmonary Atelectasis, Obesity Hypoventilation Syndrome, Magnetic Resonance Imaging
- Trial name
- NCT02523352
- Testing
- Non-Invasive Ventilation, Esophageal catheter positioning
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Atelectasis
Effects of Small-dose S-ketamine on Anesthesia-induced Atelectasis in Anesthetized Patients Accessed by Pulmonary Ultrasound
Background: Atelectasis occurs in the majority of patients with general anesthesia, which can lead to postoperative pulmonary complications (PPCs) and affect the postoperative outcome.
- Trial name
- NCT04745286
- Testing
- S-ketamine, normal saline group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Pediatric Lung Atelectasis
Effectiveness of Ultrasound-guided Lung Ventilation in Determining the Optimum Inspiratory Pressure in Pediatric Patients
This study aimed to show the Effectiveness of Ultrasound-guided Lung Ventilation to determine the appropriate level of inspiratory pressure sufficient to provide adequate pulmonary ventilation with the resolution of the…
- Trial name
- NCT06188169
- Testing
- Increasing the inspiratory pressure if atelectasis detected by US
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Atelectasis
Effect of Hyperoxia and Hypergravity on Lung Ventilation and Perfusion
The primary aim of this project is to get further knowledge on the effects of + Gz accelerations and hyperoxia on lung ventilation in humans.
- Trial name
- NCT01993394
- Testing
- hypergravity, gas mixture
- Where
- 2 sites in France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Atelectasis, Compliance, Patient
Restoration of Pulmonary Compliance After Laparoscopic Gynaecologic Surgery Using a Recruitment Maneuver
To investigate the hypothesis that an alveolar recruitment maneuver after the release of pneumoperitoneum would restore the lung compliance to the baseline values after a laparoscopic gynaecologic surgery.
- Trial name
- NCT06203665
- Testing
- Recruitment Maneuver
- Where
- Greece
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Panagiota Griva
Undergoing Surgery, Perioperatif Atelectasis
Effect of Ultrasound-assisted Lung Recruitment Maneuver on Preventing Perioperative Atelectasis
This study is based on the hypothesis that recruitment maneuver reduces perioperative atelectasis and associated complications, and lung ultrasonography can be used to detect this.
- Trial name
- NCT06770179
- Testing
- recruitment maneuver, positional recruitment maneuver
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Atelectasis, Postoperative, Pulmonary Complication
Evaluation of Perioperative Lung Ultrasound Scores (LUS) in Living Donor Nephrectomy Surgeries
Living donor nephrectomy surgeries can be performed in lateral position with laparoscopic technique which necessitates pneumoperitoneum. Considering the position and the pneumoperitoneum, lungs can be affected macroscopically.
- Trial name
- NCT05815888
- Testing
- Lung Ultrasound Score
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Infants Aged 0 Days to 13 Months Scheduled for Elective Surgery
Effect of Pressure Support Ventilation During Anesthetic Emergence on Postoperative Atelectasis in Infant
Atelectasis occurs in patients of all ages who receive mechanical ventilation under general anesthesia, and although fatal cases are rare, it is known as a cause of postoperative hypoxia or fever.
- Trial name
- NCT05373589
- Testing
- conventional ventilation, group C, pressure support, group PS
- Where
- South Korea
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Adverse Effect of Unspecified General Anesthetics
Effect of Coughing on Oxygenation in the Post Anaesthetic Care Unit
General anaesthesia causes small areas of lung to collapse (referred to as atelectasis) and many strategies are used to prevent or reverse this, but these strategies only temporarily improve lung function and do not persist into…
- Trial name
- NCT01314287
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- NHS Research and Development