Clinical trials: Lung Compliance
Cystic Fibrosis
Changes in Adherence After Playing "My Life With CF" Game
Nonadherence to treatment regimes among patients with cystic fibrosis (CF) is well documented in the literature. Unfortunately, few interventions have been successful at improving adherence rates in this patient population.
- Trial name
- NCT00688051
- Testing
- My Life with CF game
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Lumbar Spine Stenosis, Lumbar Disc Herniation
Dynamic Compliance-Guided Ventilation in Lumbar Surgery
Postoperative pulmonary complications are a frequent cause of morbidity following lumbar stabilization surgery. Conventional ventilation strategies may not adequately reflect intraoperative changes in respiratory mechanics…
- Conditions
- Lumbar Spine Stenosis, Lumbar Disc Herniation, Ventilator-Induced Lung Injury, Postoperative Complications
- Trial name
- NCT07349719
- Testing
- Dynamic Compliance Guided Ventilation, Standard Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara City Hospital Bilkent
Vaccine Hesitancy
Investigation on the Hesitancy of COVID-19 Vaccination Among Liver Transplant Recipients in China
On WeChat platform, through a point-to-point connection, and carry on the questionnaire survey to collect information of liver transplant recipients followed-up by the department of Liver Surgery, Renji Hospital Shanghai Jiao…
- Trial name
- NCT05532592
- Testing
- Perceptions and attitudes towards COVID-19 and COVID-19 vaccine
- Where
- China
- Volunteers
- 449 people
- Sponsor
- RenJi Hospital
COPD, Coronary Artery Calcification
Quebec Lung Cancer Screening PLUS Trial
Does an educational intervention for untreated COPD and cardiovascular disease which is integrated in an existing lung cancer screening program improve guideline concordant medication adherence at 12 months
- Trial name
- QLC+ (NCT05444062)
- Testing
- Educational material and treatment recommendations for patients, general practitioners and pharmacists
- Where
- Canada
- Volunteers
- 330 people
- Sponsor
- Nicole Ezer, MD, FRCPC, MPH
COVID-19 Infection
Evaluation of an Interactive Risk Information Tool to Increase COVID-19 Vaccination Incidence in Vaccine-hesitant People
Coronavirus (COVID-19) vaccines have saved millions of lives since release and remain a key tool in the fight against the pandemic.
- Trial name
- iWILL (NCT05193903)
- Testing
- Simulation, Text
- Where
- Germany
- Volunteers
- 1,188 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Asthma
Influence of an Asthma Education Programme on Asthma Control During Pregnancy
Asthma is the most frequent respiratory disease during pregnancy. In a third of cases, the level of asthma control can decrease during the pregnancy, especially between the 29th and the 36th week.
- Trial name
- NCT01345396
- Testing
- Health education about asthma
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Vaccination, Covid19
The Impact of Theory-based Messaging on Covid-19 Vaccination Intentions
Uptake of vaccination against COVID-19 is key to controlling the pandemic. However, a significant proportion of people report that they do not intend to have a vaccine, often because of concerns they have about its side effects…
- Trial name
- NCT04813770
- Testing
- Theory-based messages, General messages
- Where
- United Kingdom
- Volunteers
- 1,113 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Acute Respiratory Distress Syndrome (ARDS)
Validation of Digital Chest-X-ray (CXR) to Assess Lung Recruitment in ARDS
Lung recruitability is essential for optimal Positive end-expiratory pressure (PEEP) selection in ARDS patients. It is defined as the potential for the non aerated or poorly aerated lung mass to become aerated due to the increase…
- Trial name
- RECRUTEX (NCT02081105)
- Testing
- PEEP of 5 or 15 cm H2O
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Hospices Civils de Lyon
SARS-CoV Infection
Comparison of Strategies Based on RT-PCR or Antigenic Test for the Screening of SARS-CoV-2 Infection (COVID-19).
The virological diagnosis of SARS-CoV-2 infection is pivotal for the control of the outbreak by large screening of a- or pauci-symptomatic subjects.
- Trial name
- AutoCoV (NCT04859023)
- Testing
- saliva sample combined to an anterior nare self-swabbing (Self-samples), saliva sample (Self-sample), Survey of SARS-COV-19 knowledge
- Where
- France
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Cystic Fibrosis
Airway Secretion Clearance in Cystic Fibrosis
The purpose of this study is to compare the effect of three airway secretion clearance techniques (chest physical therapy, flutter device and high frequency chest wall oscillation) on decline in pulmonary function over a three…
- Trial name
- NCT00839644
- Testing
- High frequency chest wall oscillation, Oscillatory Positive Expiratory Pressure, PD&P: Postural drainage and percussion
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- University of Colorado, Denver
Patient Adherence
Efficacy Of An Education Plan And Adherence Follow-Up To The Exercise In Patients With COPD
Chronic obstructive pulmonary disease is one of the main causes of morbidity and mortality worldwide, according to recent publications of the World Health Organization, its main feature is the response to noxious particles of…
- Trial name
- NCT05204498
- Testing
- Education plan and adherence to exercise
- Where
- Colombia
- Volunteers
- 31 people
- Sponsor
- Clínica de Occidente S.A
Patient Hospitalized in Disease Infectious Unit, Patient Hospitalized in Intensive Reanimation Unit
Study of the Consequences of Infection on Compliance of Modalities of Decisions of Limitations and Stops of Treatments (COVID-19-LAT)
This survey is performed to examine if during the Covid's crisis, the practitionner's have respected the modalities of the law about the end of life, in particular concerning limitations and stop of therapeutics
- Conditions
- Patient Hospitalized in Disease Infectious Unit, Patient Hospitalized in Intensive Reanimation Unit, Patient Hopsitalized in Internal Medicine Unit
- Trial name
- COVID-19-LAT (NCT04452487)
- Testing
- decisions of limitations and stop processing
- Where
- 3 sites in France
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Clermont-Ferrand
COPD, Medication Adherence
Medication Adherence Research in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death, affects over 24 million people in the US and is the leading cause of disability with projected healthcare costs at almost $50 billion.
- Trial name
- MARC (NCT03174704)
- Where
- 2 sites in United States
- Volunteers
- 314 people
- Sponsor
- Johns Hopkins University
COVID-19, Vaccine Hesitancy
Online Games to Help Canadian and U.S. Adults Identify COVID-19 and Vaccine Misinformation: Three Sequential Randomized Studies
COVID-19 misinformation contributed to vaccine hesitancy and preventable illness. This record covers three sequential randomized studies (conducted in Canada and the United States, November-December 2020) testing whether a brief…
- Conditions
- COVID-19, Vaccine Hesitancy, Health Misinformation, Communication
- Trial name
- NCT07758309
- Testing
- Gamified misinformation refutation quiz, Refutational text (active control)
- Where
- United States
- Volunteers
- 3,637 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Diarrhoeal Disease, Respiratory Infection
Water Filters and Improved Cookstoves in Western Rwanda
DelAgua Health Rwanda (Implementation) Ltd. together with Rwanda Ministry of Health (MoH) are delivering an intervention, consisting on the free distribution of one advance water filter and one improved cookstove to all household…
- Conditions
- Diarrhoeal Disease, Respiratory Infection, Pneumonia
- Trial name
- NCT02239250
- Testing
- Water filter and cookstove
- Where
- Rwanda
- Volunteers
- 1,582 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Stroke
The Acute and Chronic Effects of a Heel Raise Programme on Central Blood Pressure, Arterial Compliance and Oxygen Perfusion After Stroke
Physical inactivity and increased sedentary time are linked to increased blood pressure and may cause decreases in peripheral and cerebral oxygen perfusion in stroke survivors.
- Trial name
- NCT03423433
- Testing
- Heel raise intervention
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Winchester
Asthma
RCT of a Written Action Plan vs. Usual Care in Children With Acute Asthma
The objective of the proposed large, high-intensity, randomised controlled trial is to evaluate the real-life effectiveness of providing a written action plan to asthmatic children discharged from the emergency department (ED) or…
- Trial name
- NCT00381355
- Testing
- Written Action Plan for Acute Asthma
- Where
- Canada
- Volunteers
- 218 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pulmonary Disease, Asthma
Influence of Inhaler Compliance on the Treatment of Asthma Patients
The major goal of "Influence of Inhaler Compliance on the Treatment of Asthma Patients" is to explore compliance rate outcome in adult asthmatic patients (20-80 years old) with mild to moderate persistent asthma according to…
- Trial name
- NCT06108908
- Testing
- Reminder
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Taipei Medical University Hospital
Cystic Fibrosis, Adherence, Medication
The Impact of Patch Rx Technologies on Adherence to Vitamin and Trikafta Therapies in Patients With Cystic Fibrosis
This proposed pilot study will assess if the Patch Technology system will increase adherence in patients with cystic fibrosis followed at the UTHSCSA Cystic Fibrosis Center.
- Trial name
- NCT04684823
- Testing
- Patch Cap, Patch App
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Vaccination Refusal, COVID-19
Digital Applications to Monitor Novel Coronavirus Disease and Response in Colombia - Syndromic and Vaccination Surveillance
Brief Summary: The main objective of this activity is to assess the effectiveness of different messaging strategies (factual, narrative, mixed and a control) to promote COVID-19 adult vaccination.
- Trial name
- DIAMOND-R (NCT05764174)
- Testing
- Factual messages, Narrative message, Mixed message
- Where
- United States
- Volunteers
- 2,409 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health