Clinical trials: Lung Compliance
Chronic Disease, Asthma
Feasibility of Ripple Health Smart Pill Caps in Clinical Settings
The purpose of this research is to determine whether Ripple Health Smart Medicine Bottle Caps can allow for better interface medication administration than traditional pill bottles.
- Trial name
- NCT05192928
- Testing
- Ripple Health Smart Pill Cap
- Where
- 4 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Manan Shukla
Dynamic Lung Compliance
Effects of Changes in Driving Pressure on Intraoperative Pulmonary Dynamic Compliance and PaO₂/FiO₂ Ratio in Laparoscopic Sleeve Gastrectomy
The goal of this prospective intervention study is to determine whether individualized positive end expiratory pressure (PEEP) titration targeting the minimum Driving pressure (ΔP) during LGS operation improves intraoperative…
- Trial name
- PEEP (NCT07494240)
- Testing
- incremental peep
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Beni-Suef University
Asthma
Effectiveness of an Integrated Care Program on Asthma Control and Inhaled Corticosteroids Adherence
The investigators propose to implement and evaluate an integrated care program for enhancing the care of patients with asthma in a region of Quebec province, Canada.
- Trial name
- RESPIRE (NCT02093013)
- Testing
- Integrated care program
- Where
- Canada
- Volunteers
- 349 people
- Sponsor
- Laval University
COPD
ICE COPD PikoLogic® Cohort Study.Implementation, Compliance, and Effectiveness of Integrating the PikoLogic®
This is a two-step observational cohort study evaluating the impact of adding PikoLogic® to the current disease management COPD discharge protocol subsequent to an admission for COPD exacerbation.
- Trial name
- ICE (NCT02341157)
- Sponsor
- University of Louisville
Pulmonary Arterial Hypertension
Observational Description of Compliance for the Daily Ventavis Use Via the Insight Program in Class III Pulmonary Arterial Hypertension Patients
This prospective, non-interventional, multi-center study documents observational data on subjects under routine treatment of Pulmonary Arterial Hypertension, functional class III with inhaled Iloprost administered with I-Neb AAD…
- Trial name
- DAILY (NCT01781052)
- Testing
- Ventavis (Iloprost, BAYQ6256)
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Bayer
COPD, Medication Adherence
Medication Adherence Research in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is the third leading cause of death, affects over 24 million people in the US and is the leading cause of disability with projected healthcare costs at almost $50 billion.
- Trial name
- MARC (NCT03174704)
- Where
- 2 sites in United States
- Volunteers
- 314 people
- Sponsor
- Johns Hopkins University
Interstitial Lung Disease, Comorbidities and Coexisting Conditions
Taiwan Interstitial Lung Disease Multi-center Investigation and Registry
The Taiwan Interstitial Lung Disease (ILD) Multi-center Investigation and Registry aims to evaluate the long-term outcomes of patients with fibrotic interstitial lung disease.
- Conditions
- Interstitial Lung Disease, Comorbidities and Coexisting Conditions, Pulmonary Arterial Hypertension, Treatment Adherence
- Trial name
- TAILI (NCT06476470)
- Where
- Taiwan
- Volunteers
- 10,000 people
- Sponsor
- Taichung Veterans General Hospital
Medium Flow Anesthesia, Minimal Flow Anesthesia
Assessing Lung Dynamics and Respiratory Functions in Minimal Flow Anesthesia: A Prospective Study
The patients were randomized into two groups medium flow anesthesia (MeFA) and minimal flow anesthesia (MiFA). While MeFA received medium flow anesthesia with 2 lt/min, MiFA received minimal flow anesthesia with 0.5 lt/min fresh…
- Conditions
- Medium Flow Anesthesia, Minimal Flow Anesthesia, Pulmonary Function Test, Compliance, Patient
- Trial name
- NCT06055335
- Testing
- Medium flow anesthesia, Minimal flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Asthma
This Study Compared an in Home Asthma Management Program Provided by Nurses or Respiratory Therapist
This study compared an in-home asthma management program provided by nurses or respiratory therapists to see if those receiving program had fewer hospitalizations, clinic and emergency room visits and higher levels of…
- Trial name
- NCT00639847
- Testing
- In-home asthma management program (AMP) provided by nurses, In-home asthma management program (AMP) provided by respiratory therapists
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
COVID-19
COVID-19 Vaccine Hesitancy Counseling Intervention for Pharmacists
The goal of this clinical trial is to test if virtual facilitation (e.g., video coaching) increases rural pharmacists' ability to implement COVID-19 vaccine hesitancy counseling when compared to a "standard" implementation…
- Trial name
- NCT05926544
- Testing
- Standard implementation webinar and online training, Virtual facilitation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma
RCT of a Written Action Plan vs. Usual Care in Children With Acute Asthma
The objective of the proposed large, high-intensity, randomised controlled trial is to evaluate the real-life effectiveness of providing a written action plan to asthmatic children discharged from the emergency department (ED) or…
- Trial name
- NCT00381355
- Testing
- Written Action Plan for Acute Asthma
- Where
- Canada
- Volunteers
- 218 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Lung Cancer (NSCLC)
Patient Needs and Preferences for NSCL Cancer Treatment Monitoring
The qualitative phase of the study will consist of focus group discussions (FGDs) with patients, caregivers, and clinicians. The aim is to explore the most relevant aspects of the experience of patients with lung cancer during…
- Trial name
- UNIFIED (NCT07909343)
- Testing
- Focus Group Discussion
- Where
- Italy
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European Institute of Oncology
COPD
Optimization of Pulmonary Rehabilitation Programmes: the OPTION Study
Chronic obstructive pulmonary disease (COPD) has a profound impact on the lives of individuals who suffer from it. Participants with COPD are often caught in a downward spiral that goes from chronic airflow limitation to…
- Trial name
- OPTION (NCT01933308)
- Testing
- Continuous high intensity training-CT80, Training at ventilatory threshold-CTVT, Interval training-IT
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Véronique Pépin
COVID-19, Vaccine Hesitancy
COVID-19 Disease & Vaccine Survey in Africa
The COVID-19 pandemic is a public health concern; for which the WHO recommends protective measures and vaccination. There is inadequate data on the impact of COVID-19 vaccination and control measures in Africa.
- Trial name
- NCT05950243
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Advanced Lung Cancer, Cancer-related Fatigue
Evidence-Based Nursing Plus Progressive Exercise for Cancer-Related Fatigue in Advanced Lung Cancer
This study aims to evaluate the effectiveness and safety of evidence-based nursing combined with progressive exercise training in patients with advanced lung cancer undergoing chemotherapy.
- Trial name
- ENPE-CRF (NCT07498972)
- Testing
- Evidence-Based Nursing, Progressive Exercise Training, Routine Nursing Care
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanxi Province Cancer Hospital
Bariatric Surgery
Does Pulmonary Compliance Optimization Through PEEP Manipulations Reduces the Incidence of Postoperative Hypoxaemia in Bariatric Surgery?
General anesthesia, even in patients in good health, impairs gas exchanges and ventilatory mechanics. These effects result primarily from atelectasis formation.
- Trial name
- NCT02579798
- Testing
- PEEP (positive end-expiratory pressure)
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Brugmann University Hospital
Preference, Patient, Pharmacist-Patient Relations
Preferences of Patients Treated With Oral Cancer Drugs and Informal Caregivers for Pharmaceutical Consultation in Hospital
To ensure the safe use of oral anticancer drugs, oncology pharmacy consultations (OPCs) have been established in France. Their goal is to provide the patient with the means to identify, prevent and limit adverse effects and to…
- Conditions
- Preference, Patient, Pharmacist-Patient Relations, Caregiver, Cancer
- Trial name
- IMPLICATION (NCT05970471)
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Patient Adherence
Efficacy Of An Education Plan And Adherence Follow-Up To The Exercise In Patients With COPD
Chronic obstructive pulmonary disease is one of the main causes of morbidity and mortality worldwide, according to recent publications of the World Health Organization, its main feature is the response to noxious particles of…
- Trial name
- NCT05204498
- Testing
- Education plan and adherence to exercise
- Where
- Colombia
- Volunteers
- 31 people
- Sponsor
- Clínica de Occidente S.A
Cystic Fibrosis
Coping Compliance and Adjustment in Adolescents With Cystic Fibrosis
In this research, we will use established surveys to look at the relationship between various styles of coping with a disease, religious coping styles, treatment compliance, locus of control, broad measures of mental health and…
- Trial name
- NCT00577252
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Akron Children's Hospital
ARDS, Human, Lung Injury, Acute
Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients
The goal of this interventional crossover study, in intubated and mechanically ventilated Acute Respiratory Distress Syndrome (ARDS) patients, is to compare two positive end-expiratory pressure (PEEP) titration techniques…
- Conditions
- ARDS, Human, Lung Injury, Acute, Respiratory Distress Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT03202641
- Testing
- PEEP ARDSnet, PEEP LRM
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital