Clinical trials: Lung Function Changes
Covid19, Physical Disability
Physical Rehabilitation of COVID-19 Survivors by Heat Therapy
Older adults and people with underlying medical conditions are at higher risk for developing serious complications related to SARS-CoV-2 resulting in prolonged sequelae.
- Trial name
- NCT04673318
- Testing
- heat therapy, exercise training
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Pulmonary Disease, Chronic Obstructive (COPD), Cognitive Impairment
COPD-Related Physiology and the Brain
COPD is the third leading cause of combined morbidity, disability, and mortality in the United States and is often associated with cognitive impairment.
- Trial name
- NCT03269721
- Testing
- Neuropsychological Assessment, Spirometry, Arterial Blood Gas
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Karin Hoth
Discomfort Symptoms, Changed Lung Function
Dose Response Relations for Health Effects Caused by Office Dust
The study is focused at the dose response relation for office dust and such office dust spiked with components from fungi known from damp buildings.
- Trial name
- NCT00143637
- Testing
- Office dust, clean air
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Ozone, Exercise Intensity
Investigating Changes in Responses to Controlled Effective Doses of Ozone at Different Exercise Intensities
The project will look to investigate whether exercise during ozone exposure performed for a shorter duration at a higher intensity is more harmful than exercise performed for a longer duration at a lighter intensity.
- Trial name
- NCT06513754
- Testing
- Ozone, Heavy Intensity, Moderate Intensity
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michael Koehle
Dyspnea During Pregnancy, Physiological Changes in Pregnancy
Breathing Exercises Versus Incentive Spirometry in Third-Trimester Pregnancy
Shortness of breath (dyspnea) is commonly experienced during the third trimester of pregnancy due to physiological changes affecting the respiratory system.
- Conditions
- Dyspnea During Pregnancy, Physiological Changes in Pregnancy, Reduced Functional Endurance
- Trial name
- NCT07365163
- Testing
- Deep Breathing Exercises, Volume-Oriented Incentive Spirometry
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Lahore
COVID-19
Brain Function Changes Following COVID-19 Infection
The global COVID-19 pandemic has now led to millions of infections worldwide. It produces long-lasting changes in the general physiology of multiple organs, including the brain.
- Trial name
- NCT05961618
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Allergic Rhinitis, Allergy
Pollutant Altered Allergic Responses
This study is designed to investigate whether exposure to particulate air pollution increases the allergic response to allergens.
- Trial name
- NCT00011440
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Asthma
Lung Function of Asthmatic Children by Nebulized MgSO4
Asthma is a common chronic respiratory illness which results in frequent wheezing, cough,reduced quality of life. Standard treatment for asthma attack includes oxygen therapy, β2-agonists (e.g.
- Trial name
- NCT01799109
- Testing
- Magnesium Sulfate & albuterol, albuterol, magnesium
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Insulin Resistance, Decreased Pulmonary Function
Associations of Exposure to Phthalates With Insulin Resistance and Epigenetic Change
Phthalate is an endocrine disrupting chemical, which works as an anti-androgenic agent. Phthalate is mainly used as PVC plasticizer and easily found in commonly used products such as electronic device, paint, lubricant…
- Trial name
- NCT02284477
- Testing
- non- PVC containing packing materials, PVC containing packing materials
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Gastroparesis
Gastroparesis in Cystic Fibrosis
The purpose of this research is to determine if an investigational device called the 13C-Spirulina Gastric Emptying Breath Test (GEBT), can accurately diagnose gastroparesis (delayed emptying of the stomach) in patients with…
- Trial name
- NCT05223881
- Testing
- 13^C Spirulina Platensis Gastric Emptying Breath Test (GEBT)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Air Pollution, mHealth Intervention
1/2- Bangladesh Center for Global Environmental and Occupational Health- Bangladesh
Almost 3 billion people worldwide, including 89% people in Bangladesh, are exposed to harmful household air pollutants (HAP) emitted from combustion of biomass (wood, agricultural residue, cow dung, etc.) fuel use for cooking.
- Conditions
- Air Pollution, mHealth Intervention, Cardiopulmonary Function, Immune Function
- Trial name
- GEOHealth-II (NCT05570552)
- Testing
- mHealth based behavioral change communication intervention
- Where
- Bangladesh
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Post Operative Pain
Does the Application of a Bilateral-dual Transverse Abdominal Plane (TAP)Block Have an Influence on Lung Function?
TAP-block (Transverse Abdominal Plane) block is a method of regional anesthesia used after abdominal surgery. The method is often applied ultra-sound guided.
- Trial name
- NCT01254812
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Esophageal Cancer, Esophagectomy
Oesophagectomy and Chest Wall and Respiratory Function
Open surgery for esophageal cancer commonly involves large incisions in the chest, associated with a high rate of pulmonary complications (30-50%).
- Conditions
- Esophageal Cancer, Esophagectomy, Respiratory Function Loss
- Trial name
- NCT03835273
- Testing
- 3D motion capture system, Incentive spirometry, Questionnaires
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Acute Lymphatic Leukemia, Lymphoma
More Than Just X-Rays - Imaging of Chemotherapy-induced Morphological and Functional Cardiovascular and Lung Changes After Childhood ALL and Other Cancers - a Monocentric Late Effects Study (MaximALL)
In this study, we investigate the cardiopulmonary health of survivors who underwent cancer treatment for acute lymphoblastic leukemia (ALL) or lymphoma during childhood, compared with healthy controls.
- Trial name
- MaximALL (NCT07705178)
- Testing
- QOL assessment, Neuropsychological, Spirometry, DLCO measurement
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Obesity (BMI>30)
Machine Learning Prediction of Respiratory Muscle Changes and Ventilatory Responses After Incretin-Based Therapy in Obesity
This study aims to evaluate changes in respiratory function, respiratory muscle performance, and ventilatory responses following incretin-based therapy in individuals with obesity, and to identify predictors of these changes…
- Trial name
- NCT07663591
- Testing
- Incretin-based therapy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biruni University
Sleep Bruxism, Sleep Disorder
Relationship Between Selected Parameters and Bruxism
Bruxism is a common phenomenon. It is estimated that its prevalence in the adult population is 8-31%. Bruxism occurring during sleep is the activity of the masticatory muscles that appear during sleep, which can be rhythmic or…
- Conditions
- Sleep Bruxism, Sleep Disorder, Psychosomatic Disorder, Pain
- Trial name
- WMU1/2019 (NCT04214561)
- Testing
- Polysomnography
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Using Functional Lung MRI to Explore Pulmonary Perfusion Changes in Patients With Pulmonary Fibrosis and Emphysema Syndrome
Magnetic Resonance Lung Function Imaging Study of Pulmonary Fibrosis Combined With Emphysema Syndrome
This study intends to use magnetic resonance pulmonary function imaging technology to explore imaging markers for early diagnosis of patients with CPFE.
- Trial name
- NCT06431555
- Testing
- MRI
- Where
- China
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Beijing Chao Yang Hospital
Pain, Postoperative, Pulmonary Atelectasis
Paravertebral Block Versus Erector Spinae Plane Block for Modified Radical Mastectomy in Womens.
postoperative pain following Modified radical mastectomy is severe specially after dissection of tissues .paravertebral plane block provides an excellent postoperative analgesia for women's,but it carry the risk of pneumothorax…
- Conditions
- Pain, Postoperative, Pulmonary Atelectasis, Mastectomy
- Trial name
- NCT03614091
- Testing
- Erector spinae plane block, Paravertebral plane block
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy Young Children
" ISynchroızed Swımmıng And Free Style Swımmıng
This prospective observational cohort study aimed to investigate the effects of swimming style on pulmonary function and flexibility in young female swimmers.
- Trial name
- NCT07126691
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Diaphragmatic Function, Lung Function
Pulmonary Function Changes and Diaphragmatic Paralysis Following Ultrasound Guided Supraclavicular Brachial Plexus Blockade: The Effects of Decreased Local Anesthetic Volume
This clinical trial is being conducted to study lung function and movement of the major muscle involved in breathing (the diaphragm) after a brachial plexus nerve block (nerve "freezing").
- Trial name
- NCT01048021
- Testing
- Supraclavicular Block
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba