Clinical trials: Lung Nodule
Lung Nodules, Peripheral Lung Lesions
Shape-Sensing Robotic-Assisted Bronchoscopy for Diagnosis of Peripheral Pulmonary Nodules in Korea
What is this study about? This study tests a new robotic technology to take tissue samples from lung nodules (small spots in the lungs). Some lung nodules are cancer, but doctors need a tissue sample to know for sure.
- Conditions
- Lung Nodules, Peripheral Lung Lesions, Pulmonary Nodules, Lung Cancers
- Trial name
- ULSAN-ION (NCT07057648)
- Testing
- Shape-sensing Robotic-assisted Bronchoscopy (ssRAB)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ulsan University Hospital
Video-assisted Thoracic Surgery, Pulmonary Nodules
Pulmonary Nodule Localization Prospective Validation
Localization is the key for successful excision of small target nodules under thoracoscopy, but the procedure also brings risks to patients. However, the criteria is still unclear.
- Trial name
- NCT04690790
- Testing
- Thoracoscopy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- E-DA Hospital
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
An Exploratory Clinical Study on the Safety and Efficacy of Autologous NK Cells in the Treatment of Pulmonary Nodules
A single-center, open-label dose-escalation design to evaluate the safety and efficacy of KN5001 in patients with pulmonary nodules.
- Trial name
- NCT07185035
- Testing
- KN5001
- Where
- China
- Volunteers
- 24 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Lung Neoplasms, Family Research
A Prospective Cohort of Pulmonary Ground Glass Nodules Patients With Family History.
The aim of the present prospective cohort study (GGN-F) is to study the family aggregation of pulmonary ground glass nodules via the questionnaire survey and to investigate the underlying genetic mechanism via the biobank.
- Trial name
- GGN-F (NCT04220268)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Guangdong Provincial People's Hospital
Pulmonary Infection, Pulmonary Nodule
Remimazolam for Bronchoscopy in High-Risk Patients
Bronchoscopy is currently widely used for the diagnosis and treatment of various respiratory diseases. However, the operation of bronchoscopy is irritating, causes a strong stress response, and shares the airway with the patient…
- Conditions
- Pulmonary Infection, Pulmonary Nodule, Phthisis, Endotracheal Tumour
- Trial name
- NCT07395596
- Testing
- propofol and alfentanil, remimazolam combined with propofol and alfentanil
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Lung Cancer Screening
Clinical Evaluation of the Lung Cancer AI-based Decision Support Tool in Low-Dose Lung CT
The goal of this observational study is to clinically validate the accuracy of an AI-based decision support tool-the Lung Cancer Detection System (LCDS)-for detecting lung nodules in asymptomatic adults aged 50-79 with a history…
- Trial name
- GenMedAILCSD1 (NCT07052773)
- Testing
- Lung Cancer Detection System (LCDS)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Genesis Medical AI
Solitary Pulmonary Nodule
Evaluate the Auxiliary Diagnostic Value of Circulating Tumor Cells in Benign and Malignant Lung Nodules
By testing the CTC number of new solitary pulmonary nodule patient, evaluating the correlation of CTC number and benign and malignant lung nodules auxiliary diagnosis, the correlation of CTC number and the size of lung nodules of…
- Trial name
- NCT02653859
- Volunteers
- 50 people
- Sponsor
- GenoSaber
Microwave Ablation, Lung Cancer
Microwave Ablation in Ground Glass Nodules
GGO was commonly observed recently.Radiofrequency ablation has been widely applied in the treatment of patients with GGO. No study had explored the microwave ablation in the treatment of GGO.
- Trial name
- NCT03490890
- Testing
- Microwave ablaton
- Where
- 15 sites in China
- Volunteers
- 200 people
- Sponsor
- Shandong Provincial Hospital
Solitary Pulmonary Nodule, Lung Cancer
Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach
Patients presenting with solitary or multiple lung nodules often require tissue confirmation in order to guide further management and determine if the lesion is benign or malignant.
- Trial name
- NCT00925210
- Testing
- Sequential pEBUS - ENB
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Video-assisted Thoracic Surgery, Lung Cancer
Mixed Reality Technique Combined With 3D Printing Navigational Template for Localizing Pulmonary Nodules
This study evaluates the viability and accuracy of preoperative mixed reality technique combined with three-dimensional printing navigational template guided localizing pulmonary small nodules.
- Conditions
- Video-assisted Thoracic Surgery, Lung Cancer, Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
- Trial name
- MR&3D Local (NCT04552054)
- Testing
- Mixed Reality+ 3D printing guided localization, Computerized Tomography guided localization
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Wen-zhao ZHONG
Pulmonary Nodule, Solitary
Is Bronchoscopy Necessary in the Preoperative Workup of GGO Lung Cancer?(ECTOP-1005)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1005). It aims to evaluate the role of flexible bronchoscopy in the pre-operative workup of ground glass opacity featured lung cancer.
- Trial name
- NCT03591445
- Testing
- Flexible Bronchoscopy
- Where
- China
- Volunteers
- 615 people
- Sponsor
- Fudan University
Lung Cancer
Evaluation of the Archimedes™ System for Transparenchymal Nodule Access
The Archimedes System is an image-guided navigation system used to access tissue samples in the lungs. This study is being conducted to confirm the performance of the Archimedes System in patients who are scheduled for standard…
- Trial name
- EAST (NCT02460120)
- Testing
- Archimedes System
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Broncus Medical Inc
Lung Cancer
Amino Acid Tracer (FACBC) Positron Emission Tomography for Lung Nodule
This study will look at how the [18]FACBC goes into the lung nodules. This will hopefully lead to the development of better imaging techniques to look at lung nodules.
- Trial name
- SPN (NCT01502670)
- Testing
- 18F-FACBC Radiotracer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Pulmonary Nodules, Lung Neoplasms
A Multicenter Cohort Study of AI-Based Methods for Pulmonary Nodule Diagnosis and Follow-up
This is an observational, multicentre study. The primary objective of this study was to evaluate the diagnostic performance and clinical applicability of artificial intelligence models for pulmonary nodule segmentation…
- Conditions
- Pulmonary Nodules, Lung Neoplasms, Artificial Intelligence (AI)
- Trial name
- NCT07815483
- Volunteers
- 16,880 people
- Sponsor
- Shanghai East Hospital
Solitary Pulmonary Nodules
Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis
The purpose of this study is to evaluate the imaging performance of Dual Energy and Digital Tomosynthesis (DE-DT) application against the commercially available predicate devices.
- Trial name
- NCT02531646
- Testing
- Radiation
- Volunteers
- 66 people
- Sponsor
- Carestream Health, Inc.
Lung Nodules, Lung Cancer
The Impact of Thoracic Paravertebral Nerve Block At Different Positions on Pain Relief in Patients Undergoing Single-Port Thoracoscopic Partial Lung Resection
Thoracic surgery is widely recognized as one of the most painful surgical procedures. Compared to open thoracotomy, video-assisted thoracoscopic surgery (VATS) offers similar therapeutic outcomes with less invasiveness…
- Trial name
- NCT06789276
- Testing
- Supine position, lateral decubitus position
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Tumor of Lung, Pulmonary Nodule
Prospective Study of Serum Marker LncRNA RP5-977B1 in Pulmonary Nodules
Based on previous studies, this project intends to use prospective studies to select patients identified by imaging as pulmonary nodules to explore the potential of RP5-977B1 in differentiating benign and malignant pulmonary…
- Trial name
- NCT06531850
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
IDEAL: Artificial Intelligence and Big Data for Early Lung Cancer Diagnosis Study
This study aims to test the use of novel CT image analysis techniques to enable a better characterisation of small pulmonary nodules.
- Conditions
- Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple, Lung Cancer
- Trial name
- IDEAL (NCT03753724)
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,293 people
- Sponsor
- University of Oxford
Lung Cancer, Precancerous Condition
Natural History of Lung Nodules Seen on CT Scans From Participants at High-Risk of Developing Lung Cancer
RATIONALE: Comparing lung CT scans from participants with lung nodules at high-risk for lung cancer may help doctors learn more about the disease and find better methods of treatment.
- Trial name
- NCT01540552
- Testing
- medical chart review, computed tomography, computer-aided detection/diagnosis
- Where
- Italy
- Volunteers
- 320 people
- Sponsor
- M.D. Anderson Cancer Center
Pulmonary Nodules, Early-Stage Lung Cancer
CT-Free Electromagnetic Navigation Percutaneous Localization for Pulmonary Nodules Undergoing Sublobar Resection
Pulmonary nodules, particularly small and non-palpable nodules, present challenges for accurate localization during sublobar lung resection.
- Trial name
- NCT07743775
- Where
- 3 sites in China
- Volunteers
- 153 people
- Sponsor
- Jianle Chen