Clinical trials: Lymph Node
Squamous Cell Carcinoma of Oral Cavity
Maintenance Tegafur-uracil in Resected Oral Cavity Cancer With ECS+
Primary Objective: To determine the 2-year distant failure rate of maintenance tegafur-uracil in patients with squamous cell carcinoma of oral cavity with extracapsular spreading of lymph nodes.
- Trial name
- NCT03121313
- Testing
- tegafur-uracil
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Chang Gung Memorial Hospital
Head and Neck Cancer
Detection of Cervical Lymph Node Metastases With a High-Resolution Positron Emission Tomography (PET) Imaging System
The goal of this clinical research study is to learn if using the PEMFlex Solo II, a high-resolution camera for PET scan imaging, on an area of the body that has, or is suspected to have cancer will give researchers the same or…
- Trial name
- NCT01030497
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Cervical Cancer
Usefulness of FDG-PET for Advanced Cervical Cancer
The objective of this study is to determinate whether the adding of FDG-PET is helpful in the treatment of advanced cervical cancer with concurrent chemoradiation.
- Trial name
- NCT00146458
- Testing
- 18F-fluorodeoxyglucose positron emission tomography
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Chang Gung Memorial Hospital
Alzheimer's Disease
Clinical Study on Deep Cervical Lymphatic Trunk Decompression Combined With Mid-Cervical Deep Lymph Node-External Jugular Vein Anastomosis for Alzheimer's Disease Treatment
The aim of this study is to evaluate the feasibility, safety, and efficacy of bilateral deep cervical lymphatic trunk decompression combined with mid and deep cervical lymph node-extracervical vein anastomosis in the treatment of…
- Trial name
- NCT06936514
- Testing
- Bilateral Cervical Deep Lymphatic Trunk Decompression Combined with Mid-Cervical Deep Lymph Node-External Jugular Vein Anastomosis for Alzheimer's Disease
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Oriental Neurosurgery Evidence-Based-Study Team
Nasopharyngeal Cancinoma (NPC), Lymph Node Metastasis
A Deep Learning Model for Diagnosing Lymph Node Metastasis in Nasopharyngeal Carcinoma(NPC)
(I) AI Model for Diagnosing Lymph Node Metastasis We developed an AI model to help diagnose whether a single lymph node in nasopharyngeal cancer has spread. The model uses MRI images of the lymph node and the area around it.
- Trial name
- NPC (NCT06829147)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Sun Yat-sen University
Virtual Staining, Lymph Node Metastasis
Evaluation of Axillary Lymph Node Metastasis Status of Breast Cancer Based on Pathological Images and Virtual Staining
The goal of this observational study is to develop an artificial intelligence model to transform unstained lymph node tissue slice images directly into stained images.
- Conditions
- Virtual Staining, Lymph Node Metastasis, Breast Cancer, Digital Pathology
- Trial name
- NCT06486155
- Volunteers
- 2,200 people
- Sponsor
- Yunnan Cancer Hospital
Esophageal Squamous Cell Carcinoma
Immunotherapy Plus Anlotinib After Surgery for Esophageal Squamous Cell Cancer With Residual Tumor and Positive Lymph Nodes
The goal of this clinical trial is to learn whether postoperative immunotherapy combined with anlotinib can help prevent or delay cancer recurrence in adults aged 18 to 75 years with locally advanced esophageal squamous cell…
- Trial name
- NCT07830355
- Testing
- Anlotinib, Anti-PD-1 Monoclonal Antibody
- Volunteers
- 75 people
- Sponsor
- Shanghai Chest Hospital
Right Hemicolectomy
Fluorescence Lymph Node Mapping for Colon Cancer Surgery
Fluorescence-guided surgery using indocyanine green can visualize the complex and diverse lymph node drainage structures for each patient and help determine the extent of dissection of the D3 lymph node tailored to the patient.
- Trial name
- CONSTELLARE (NCT07060443)
- Testing
- Indocyanine green (ICG) injection for intraoperative lymph node imaging, Standard Right Hemicolectomy (Non-ICG)
- Where
- 13 sites in South Korea
- Volunteers
- 186 people
- Sponsor
- Pusan National University Yangsan Hospital
Melanoma, Surgery
Perioperative Examination of Inflammatory Markers in Relation to Sentinel Lymph Node Biopsy in Patients With Melanoma; a Pilot Study
We want to test if an association between sentinel lymph node biopsy (SLBN) and a systemic inflammatory response can be made.
- Trial name
- NCT05817149
- Testing
- Blood samples
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Aalborg University Hospital
Breast Cancer
Docetaxel in Node Positive Adjuvant Breast Cancer
The purpose of this study was to compare disease-free survival after treatment with docetaxel in combination with doxorubicin and cyclophosphamide to 5-fluorouracil in combination with doxorubicin and cyclophosphamide in operable…
- Trial name
- TAX316 (NCT00688740)
- Testing
- Docetaxel, 5-fluorouracil, Doxorubicin
- Where
- 20 sites in United States, Argentina and 18 more
- Volunteers
- 1,491 people
- Sponsor
- Sanofi
Pancreatic Neoplasm
Core Biopsy Endo Sonography Study Evaluation of the Significance of the Pro-core® Needle
The study is designed to evaluate the diagnostic accuracy of a new designed endoscopic ultrasonography (EUS) Core biopsy aspiration needle in comparison to a conventional EUS aspiration needle in GI-tumors.
- Trial name
- COS (NCT02181140)
- Testing
- EUS guided FNA and fine needle punction
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Colon Cancer, Sentinel Lymph Node
Minimally INvasive Colon Cancer Surgery Through IMmunomics and Optical Mapping of the Sentinel Lymph Node.
The project investigates the feasibility of laparoscopic fluorescent imaging for the intraoperative detection of the sentinel lymph node (SLN) in colon cancer patients.
- Trial name
- MINIMAL (NCT03779009)
- Testing
- ICG-nanocoll (indocyanine green coupled to the human albumin colloidal particle nanocoll)
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- University Hospital, Ghent
Thyroid Cancer, Thyroid Carcinoma, Papillary
Near-infrared Fluorescence With Indocyanine Green for Identification of Sentinels and Parathyroids During Thyroidectomy
Indocyanine green (ICG) is a water-soluble organic dye that is cleared totally through the hepatobiliary system. It has a half-life of 3-4 mins, which allows repeated applications.
- Conditions
- Thyroid Cancer, Thyroid Carcinoma, Papillary, Thyroid Metastases, Thyroid Neoplasms
- Trial name
- NCT04424485
- Testing
- Total thyroidectomy (TT), Central lymph node dissection (CLND), Sentinel lymph node (SLN) bopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Umraniye Education and Research Hospital
Toxicity Due to Radiotherapy, Nasopharyngeal Carcinoma
Clincal Study of Reduced Target Radiotherapy in Nasopharyngeal Carcinoma
To determine whether subtractive radiotherapy can significantly reduce the acute side effects of radiotherapy and improve the quality of life of patients on the basis of ensuring the existing curative effect.
- Trial name
- NCT05741008
- Testing
- Target range
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Esophageal Cancer, Salvage Radiotherapy
Simultaneous Integrated Boost for Mediastinal Lymph Node Recurrence After Radical Surgery of Esophageal Cancer
Esophageal cancer (EC) ranks the seventh most diagnosed malignant tumor (572,000 new cases) and the sixth cancer-related mortality (509,000 deaths) worldwide in 2018.
- Conditions
- Esophageal Cancer, Salvage Radiotherapy, Dose-escalation, Mediastinal Lymph Node Recurrence
- Trial name
- NCT03990532
- Testing
- treatment group(phase I), treatment group (phase II)
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Ruijin Hospital
The Aim of This Study is to Determine the Influence of BMI and Lymph Node Status on OS in CRC Patients in the Long Term
BMI and Lymph Node Count in Colorectal Cancer
Background and aim: Colorectal Cancer (CRC) is one of the most frequent cancer entities in the western world. It is known that obesity is one of the major risk factors for CRC.
- Trial name
- NCT06334926
- Testing
- no intervention, retrospective data analysis
- Where
- Austria
- Volunteers
- 1,192 people
- Sponsor
- Klinikum Floridsdorf
Breast Cancer
Magnetic Tracer in the Sentinel Node Procedure in Breast Cancer: the Non-radioactive Alternative for Radio-isotopes
Rationale: In breast cancer, a sentinel node procedure is performed to investigate whether malignant cells have spread to the axillary lymph nodes.
- Trial name
- MagTrace (NCT05122585)
- Testing
- MagSeed and MagTrace in breast cancer patiënts
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Zuyderland Medisch Centrum
Rectal Cancer, Lymph Node Cancer Metastatic
Indocyanine Green-guided Lymphadenectomy in Laparoscopic Total Mesorectal Excision for Low Rectal Cancer After Neoadjuvant Chemoradiotherapy
The goal of this clinical trial is to assess the number of harvested locoregional lymph nodes in rectal cancer patients undergoing laparoscopic total mesorectal excision and indocyanine green (ICG)-guided lymphoadenectomy after…
- Trial name
- (GreenEye-CRC) (NCT05873621)
- Testing
- ICG-guided lymphadenectomy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Prostate Cancer
Trial of Modifications to Radical Prostatectomy
This trial will evaluate whether the following aspect of surgical technique influence outcome: Lymph node dissection. In some patients, scans taken before surgery show that a lymph node has cancer.
- Trial name
- NCT01407263
- Testing
- Lymph node template, Transverse versus vertical closure, antibiotic prophylaxis
- Where
- 5 sites in United States
- Volunteers
- 3,204 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Testicular Cancer
Study on the Quality of Life and Functional/Oncological Outcome of Testicular Cancer Patients
The research aims to collect data in order to report the main problems related to the testicular cancer; To reach this aim, this study proposes to create a database of the testicular cancer condition.
- Trial name
- NCT06389409
- Testing
- Observation of testicular cancer patients
- Where
- Italy
- Volunteers
- 3,000 people
- Sponsor
- IRCCS San Raffaele
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