Clinical trials: Lymph Node
Cervical Cancer
TMTP1-ICG Mapping in Laparoscopic SLN Detection in Cervical Cancer
investigators aimed to determine the validity of our novel tumor targeted fluorescent TMTP1-ICG to increased accuracy of laparoscopic SLN mapping
- Trial name
- NCT03321448
- Testing
- TMTP1-ICG, ICG
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huazhong University of Science and Technology
Breast Cancer
Axillary Reverse Mapping
It has been hypothesized that the proximity of the anatomic locations of the arm lymphatic drainage system to the breast lymphatic system in the axilla put the arm lymphatics at risk for disruption during a sentinel lymph node…
- Trial name
- NCT01381315
- Testing
- Injection of isotope, Axillary lymph node dissection
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- University of Kansas Medical Center
Breast Cancer Female
Selective Axillary Dissection After Neoadjuvant Chemotherap Yin Patients With Lymphnode-positive Breast Cancer
The aim of this observational study is to collect data regarding the selective axillary dissection tecnique of lymphnode restaging after neoadjuvant chemotherapy in patients with Breast Cancer that is lymphonode positive at the…
- Trial name
- CLYP (NCT07828925)
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cardiovascular Diseases, Coronary Aneurysm
Prevention of Coronary Aneurysms in Kawasaki Syndrome
To test the efficacy of intravenous gamma globulin (IVGG) in preventing coronary artery aneurysms in children with Kawasaki Syndrome.
- Conditions
- Cardiovascular Diseases, Coronary Aneurysm, Heart Diseases, Mucocutaneous Lymph Node Syndrome
- Trial name
- NCT00000520
- Testing
- immunoglobulins, intravenous, aspirin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Colon Cancer, Laparoscopic Colon Surgery
Analysis of Surgical and Oncologic Outcomes After Complete Mesocolic Excision or Non-complete Mesocolic Excision for Right-Sided Colon Cancer
The goal of this observational study is to investigate the efficacy and safety of a modified D3 lymphadenectomy approach compared to Complete Mesocolic Excision (CME) in patients with right-sided colon cancer.
- Conditions
- Colon Cancer, Laparoscopic Colon Surgery, Lymph Node Dissection, Robotic Surgical Procedures
- Trial name
- NCT06684223
- Where
- South Korea
- Volunteers
- 3,787 people
- Sponsor
- Asan Medical Center
Thyroid Cancer
The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study.
Cytological examination of punctured lymph nodes is the gold standard for confirming metastatic lymph node spread of differentiated thyroid cancers.
- Trial name
- Tgcyto (NCT02602717)
- Testing
- lymph nodes cyto-punction
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Lymph Node Disease
Prediction Model of CP-EBUS in the Diagnosis of Lymph Nodes
Endobronchial ultrasound (EBUS) multimodal image including grey scale, blood flow doppler and elastography, can be used as non-invasive diagnosis and supplement the pathological result, which has important clinical application…
- Trial name
- NCT04328792
- Where
- China
- Volunteers
- 1,300 people
- Sponsor
- Shanghai Chest Hospital
Endometrial Cancer
27-Inch Versus 55-Inch Monitors in Women Undergoing Endometrial Cancer Surgery
This study will compare the use of 27-inch and 55-inch endoscopic imaging monitors during minimally invasive surgery for women with endometrial cancer. Participants will be randomly assigned to one of the two monitor groups.
- Trial name
- NCT07882277
- Testing
- 27-Inch Endoscopic Imaging Monitor, 55-Inch Endoscopic Imaging Monitor
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Metehan Uzundal
Breast Cancer
Prospective Pilot Study ANDPrecise
This study aims at providing first evidence that axillary clearance by using an operation technique including the precise LigaSure instrument and closure of dead space of the axilla will result in an operation were a drain is not…
- Trial name
- ANDPrecise (NCT02292407)
- Testing
- LigaSure Precise instrument
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- The Netherlands Cancer Institute
Breast Cancer
Evaluation of Needle Core Biopsy of Axillary Sentinel Lymph Node in Breast Cancer
The purpose of the study is to determine if it is possible to identify and perform a needle biopsy of the sentinel lymph node. The investigators hope to identify breast cancer cells in the lymph nodes under the arm without making…
- Trial name
- ENCASe (NCT02046057)
- Testing
- PNB of SLN
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Loma Linda University
Prostate Cancer
A Phase 2 Study With MIP-1404 in Men With High-Risk PC Scheduled for RP and EPLND Compared to Histopathology
This was a multicenter, multi-reader, open-label, Phase 2 study assessing the safety and performance characteristics of MIP 1404 imaging in the detection of prostate gland and pelvic lymph node cancer.
- Trial name
- NCT01667536
- Testing
- Drug: 99mTc-MIP-1404
- Where
- 35 sites in United States, Belgium and 6 more
- Volunteers
- 105 people
- Sponsor
- Molecular Insight Pharmaceuticals, Inc.
Papillary Thyroid Cancer, Lymph Node Metastases
Precision Thyroid Cancer Surgery With Molecular Fluorescent Guided Imaging
Almost 50 % of papillary thyroid cancer (PTC) patients have central lymph node metastases (CLNM), which are associated with a high risk of persistent or recurrent disease.
- Trial name
- TARGET (NCT03470259)
- Testing
- IV adminstration of EMI-137, Multispectral Fluorescence Reflectance Imaging, Spectroscopy
- Where
- 2 sites in Netherlands
- Volunteers
- 19 people
- Sponsor
- University Medical Center Groningen
Vaccine-Preventable Diseases
Fine Needle aSpiration of Lymph nodEs to Study vAccine-induced Immunity
Rationale Causing a wide range of infectious diseases, including pneumonia, otitis media and meningitis, S. pneumoniae represents an important global health problem.
- Trial name
- SEA (NCT06202703)
- Testing
- Pneumococcal Vaccine
- Where
- Netherlands
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Lung Cancer Metastatic
Clinical and Molecular Findings in Patients With Cervical/Supraclavicular Metastasis From Non-small-cell Lung Cancer (NSCLC)
Despite the availability of highly effective endoscopy-based and computed tomography (CT)-based biopsy procedures, up to 50% of patients with advanced lung cancer potentially eligible for targeted therapies or immunotherapy do…
- Trial name
- ProphetaPro (NCT05706883)
- Testing
- Needle or forceps biopsy of cervical and/or supraclavicular lymph nodes, Needle, forceps or surgical biopsy of any lesion other than cervical and/or supraclavicular lymph nodes
- Where
- Italy
- Volunteers
- 348 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lymph Node Metastases
Irreversible Electroporation(IRE) For Unresectable Lymph Node Metastases(Close to Nerve)
The purpose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for unresectable Lymph Node Metastases.
- Trial name
- IRE (NCT02430766)
- Testing
- Irreversible electroporation (IRE), NanoKnife
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fuda Cancer Hospital, Guangzhou
Breast Neoplasms
The Breast Surgery EnLight and LightPath Imaging System Study
This study will correlate the resection margin status of the breast cancer tumour (WLE specimen), cavity shavings (if any) and breast cavity, and the metastatic status of axillary lymph nodes as determined by EnLight, LightPath…
- Trial name
- NCT02151071
- Testing
- EnLight, LightPath
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Lightpoint Medical Limited
Cutaneous Squamous Cell Carcinoma (CSCC)
Testing Whether Skin Cancer Has Spread to Nearby Lymph Nodes
This study is about a type of skin cancer called high-risk cutaneous squamous cell carcinoma (HRcSCC). Although most people with this type of skin cancer are successfully treated, some patients have a higher chance that the…
- Trial name
- CECRE (NCT07746258)
- Testing
- Lymphadenectomy
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Germans Trias i Pujol Hospital
Locally Advanced Non-Small Cell Lung Cancer, Stage IIIb Non-small Cell Lung Cancer
Neoadjuvant SBRT Followed by Sintilimab Plus Chemotherapy for N3-Positive NSCLC
This is a Phase II clinical trial evaluating the efficacy and safety of a new treatment approach for patients with locally advanced non-small cell lung cancer (NSCLC) that has spread to lymph nodes on the opposite side of the…
- Conditions
- Locally Advanced Non-Small Cell Lung Cancer, Stage IIIb Non-small Cell Lung Cancer, Stage IIIC Non-Small Cell Lung Cancer
- Trial name
- SACTION 2501 (NCT07309952)
- Testing
- Sintilimab, Paclitaxel, Carboplatin (AUC 5)
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Yang Hong
Sentinel Lymph Node, Breast Cancer
A Clinical Feasibility Study of a Photoacoustic Finder
Determining the prognosis of breast cancer relies significantly on axillary staging by sentinel lymph node biopsy (SLNb). The SLNb is generally performed using radioisotopes, blue dyes, or both to improve the false negative rate.
- Trial name
- NCT06412211
- Testing
- Photoacoustic finder
- Where
- South Korea
- Volunteers
- 129 people
- Sponsor
- Seoul St. Mary's Hospital
Indocyanine Green, Gastric Cancer
Randomized Controlled Trial on Effect of Lymph Node Mapping by Indocyanine Green Via Submucosal or Subserosal Injection
The purpose of this study was to evaluate whether submucosal or subserous injection of indocyanine green during laparoscopic lymphadenectomy for patients with gastric cancer was different.
- Conditions
- Indocyanine Green, Gastric Cancer, Injection Site
- Trial name
- NCT04219332
- Testing
- Subserosa injection of indocyanine green, submucosal injection of indocyanine green
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Fujian Medical University
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