Clinical trials: Lymphatic Edema
Breast Cancer, Lymphedema
Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Have Undergone Radiation Therapy for Cancer
RATIONALE: Hyperbaric oxygen therapy may be effective in repairing damaged tissue and reducing lymphedema caused by radiation therapy for cancer.
- Conditions
- Breast Cancer, Lymphedema, Perioperative/Postoperative Complications, Radiation Fibrosis
- Trial name
- NCT00077090
- Testing
- hyperbaric oxygen
- Where
- 5 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Breast Cancer, Lymphedema
Trial of Decongestive Lymphatic Therapy for Lymphedema in Women With Breast Cancer "DELTA STUDY"
The purpose of this study is to evaluate the efficacy, safety and impact on quality of life of decongestive lymphatic therapy (DLT) in women who have completed treatment for breast cancer and present with lymphedema.
- Trial name
- NCT00201890
- Testing
- Lymphatic Massage (Decongestive Lymphatic Therapy) (Arm 1)
- Where
- 9 sites in Canada
- Volunteers
- 103 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer, Lymphedema
Effect of Upper Limb Posture on Limb Volume as Expressed in Circumference Measurement in Healthy Women and in Women With Breast Cancer Related Lymphedema
Lymphedema is one side effect of breast cancer treatment. Measuring the edematous limb enables monitoring changes in the lymphedema and the effect of treatment.
- Trial name
- NCT01672125
- Testing
- circumferential measurements in different upper limb positions.
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Filarial; Infestation
Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection
Diethylcarbamazine (DEC) essentially a micro-filaricidal drug is given for 12 days as standard treatment for the clearance of W. bancrofti infection.
- Trial name
- NCT02005653
- Testing
- Diethylcarbamazine, Albendazole, Doxycycline
- Where
- India
- Volunteers
- 146 people
- Sponsor
- Indian Council of Medical Research
Lymphedema
Treatment of Lymphedema: Application of the Kinesio Taping
There are 2 parts to this study. First part: Reliability of water displacement, circumference, tonometer. Effect of taping: lifting effect measured with sonography Effect of taping: peripheral circulation measured with DRT4…
- Trial name
- NCT00155220
- Testing
- Low Stretch Bandage and Kinesio Tape
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Lymphedema
The Women In Steady Exercise Research (WISER) Survivor Trial
WISER Survivor is a one year weight loss and exercise study for sedentary breast cancer survivors who are overweight or obese with breast cancer related lymphedema.
- Trial name
- WISER Survivor (NCT01515124)
- Testing
- Exercise Intervention, Weight Loss Intervention
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Female Genital Diseases, Ovarian Cancer
Prospective Evaluation of Lymphoedema Among Patients With Gynaecological Cancer
This project will conduct a prospective, longitudinal, observational cohort study to assess the onset and incidence of lymphoedema, as well as investigate factors associated with its development among women newly diagnosed with…
- Conditions
- Female Genital Diseases, Ovarian Cancer, Cervical Cancer, Endometrial Cancer
- Trial name
- LEGS (NCT00604994)
- Where
- 6 sites in Australia
- Volunteers
- 761 people
- Sponsor
- Queensland Centre for Gynaecological Cancer
Lymphedema, Secondary Lymphedema
Feasibility of Lymph Edema-induced Reticulation Subtraction Based on Computerized Tomography
Development of lympho-proliferation reticulation quantification using CT.
- Conditions
- Lymphedema, Secondary Lymphedema, CT
- Trial name
- NCT03523494
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Ulsan University Hospital
Breast Cancer Lymphedema
Does Immediate Lymphatic Reconstruction Decrease the Risk of Lymphedema After Axillary Lymph Node Dissection
The researchers are doing this study to see if having immediate lymphatic reconstruction after axillary lymph node dissection (ALND) can decrease the development of lymphedema, a side effect of ALND.
- Trial name
- NCT04241341
- Testing
- Axillary Lymph Node Dissection with Immediate Lymphatic Reconstruction, Axillary Lymph Node Dissection without Immediate Lymphatic Reconstruction, quality-of-life questionnaires
- Where
- 7 sites in United States
- Volunteers
- 180 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer Related Lymphedema
Effects of Core-Focused Exercise Training and Kinesiology Taping in Women With Breast Cancer-Related Lymphedema
The aim of the present study is to investigate the effects of trunk- focused exercise training and kinesiology taping, in addition to standard lymphedema treatment (complex decongestive therapy-CDT) on posture, pain…
- Trial name
- NCT07673939
- Testing
- Complex Decongestive Therapy, Trunk Focused exercises, Kinesiology taping
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Breast Cancer, Pain, Chronic
The Sequelae of Mastectomy and Quadrantectomy Respect to the Reaching Movement in Breast Cancer Survivors
The hypothesis behind our study was that patients after BC surgery, who underwent quadrantectomy or mastectomy, may present a different disability respect to the upper limb on the operated side.
- Conditions
- Breast Cancer, Pain, Chronic, Pain, Postoperative, Mastectomy; Lymphedema
- Trial name
- NCT04145739
- Testing
- Rehabilitation protocol
- Where
- Italy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Primary Lymphedema
Out-of Pocket Payments in Patients With Lymphedema
Primary lymphedema is a chronic condition posing a high burden on patients. Clinical guidelines emphasize the role of compression therapy by prescription medical devices.
- Trial name
- Lymphorac2 (NCT02988479)
- Testing
- Out of pocket payments in patients
- Where
- France
- Volunteers
- 108 people
- Sponsor
- University Hospital, Montpellier
Lymphedema
Safety Study of Bevacizumab to Treat Women With a History of Breast Cancer and Suffering From Upper Extremity Lymphedema
The purpose of this study is to determine the safety and side effects of bevacizumab in subjects with lymphedema who will initially receive bevacizumab alone and then in combination with standard manual lymphatic drainage (MLD)…
- Trial name
- NCT00318513
- Testing
- Bevacizumab
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Premiere Oncology of Arizona
Lymphedema of Limb, Malignant Skin Neoplasm
Prophylactic LYMphatic Reconstruction (LYMbR) to Prevent Lymphedema After Node Dissection for Cutaneous Malignancies
Background: Lymphedema following lymph node dissection is a chronic condition that can limit physical, occupational, and social participation, impact self-image, and result in financial burden.
- Trial name
- LYMbR (NCT05136079)
- Testing
- Prophylactic lymphaticonvenous anastomosis
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Alberta Health Services, Calgary
Lymphedema, Lymphedema Arm
The Robot-LVA Study: Robot-assisted Microsurgical Lymphaticovenous Anastomosis in Breast Cancer-related Lymphedema
This study assesses the performance of robot-assisted microsurgery. Lymphaticovenous anastomosis (LVA) is the most difficult procedure in microsurgery at this moment.
- Conditions
- Lymphedema, Lymphedema Arm, Lymphedema of Upper Arm, Lymphedema of Upper Limb
- Trial name
- NCT06532955
- Testing
- Lymphaticovenous anastomosis using Microsure Motion Stabilizer, Lymphaticovenous anastomosis (manual)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Lymphedema
Study of Lymphatic Dysfunction in Primary and Secondary Lymphedema
Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose…
- Trial name
- LYMPHODYS (NCT05629026)
- Testing
- Micro-biopsies
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
Breast Neoplasms, Radiotherapy
Hypofractionated LocoRegional Radiotherapy in Breast Cancer
The primary objective of this study is to determine if hypofractionated RT delivered over 1 week to the breast or chest wall and regional nodes (26Gy in 5 daily fractions) following BCS or mastectomy, is non-inferior to…
- Conditions
- Breast Neoplasms, Radiotherapy, Lymphedema
- Trial name
- RHEAL (NCT04228991)
- Testing
- Locoregional radiation treatment - Conventional fractionation, Locoregional radiation treatment - Hypofractionation
- Where
- 20 sites in Canada
- Volunteers
- 588 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Lymphedema
Low Level Laser Treatment and Breast Cancer Related Lymphedema
Manual Lymphatic Drainage (massage therapy) with compression (wearing a tight sleeve on the arm) is the current standard of treatment for breast cancer related lymphedema (arm swelling).
- Trial name
- NCT00852930
- Testing
- laser and MLD combined, laser alone, manual lymphatic drainage
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vanderbilt University
Turner Syndrome, Peripheral Angiopathy
AVAST Anomalies Vasculaires Associées au Syndrome de Turner (Vascular Abnormalities Associated With Turner Syndrome)
Turner syndrome is a genetic condition, rare, due to the total or partial absence of one X chromosome, affecting 1/2500 newborn female. It combines almost constantly short stature and ovarian failure with infertility.
- Conditions
- Turner Syndrome, Peripheral Angiopathy, Vascular Malformation, Lymphedema
- Trial name
- AVAST (NCT02250456)
- Testing
- Echo doppler
- Where
- 6 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Strasbourg, France
Carcinoma of the Endometrium, Hysterectomy
Lymphedema After Primary Surgery for Endometrial Cancer
The purposes of this study are to determine the prevalence, size and impact on quality of life of lymphedema of the lower extremities after primary radical surgery with hysterectomy +/- pelvic - and paraaortic lymphadenectomy in…
- Conditions
- Carcinoma of the Endometrium, Hysterectomy, Lymphadenectomy
- Trial name
- LASEC (NCT02115477)
- Testing
- Lymphadenectomy
- Where
- 16 sites in Sweden
- Volunteers
- 262 people
- Sponsor
- Preben Kjolhede, MD, professor