Clinical trials: Lymphomas,
Hodgkin Lymphoma, Adult
Cardiopulmonary Function and Cerebral Blood Flow in Hodgkin Lymphoma Survivors
SURVIVORS Study participants are being asked to take part in this research study called HODNIRS because the participant is a survivor of Hodgkin Lymphoma (HL) treated with chest radiation and bleomycin at St.
- Trial name
- NCT06421987
- Testing
- Near Infrared Spectroscopy (NIRS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Relapsed or Refractory Lymphoma
HMPL-523 Food Effect and Proton Pump Inhibitor Study
A Phase 1, Open-label, 4-Period, Randomized 6-Sequence Study to Evaluate the Effect of Food and Rabeprazole, a Proton Pump Inhibitor, on the Pharmacokinetics of HMPL-523 in Healthy Volunteers
- Trial name
- NCT05571787
- Testing
- HMPL-523, Rabeprazole
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hutchmed
Diverticulitis
Diverticulitis: Antibiotics or Close Observation?
Rationale The prevalence of colonic diverticular disease is increasing in Western countries. Approximately 10 to 25% of patients with diverticular disease will eventually develop an episode of acute diverticulitis.
- Trial name
- DIABOLO (NCT01111253)
- Testing
- Amoxicillin-clavulanate
- Where
- 24 sites in Netherlands
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Dementia, Mild, Mild Cognitive Impairment
CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners
The purpose of this study is to test the adapted protocol, CAPABLE Family which builds upon the evidenced based CAPABLE program to address older adults with co-occurring physical disability and mild cognitive impairment or early…
- Conditions
- Dementia, Mild, Mild Cognitive Impairment, Disability Physical, Impairment, Cognitive
- Trial name
- NCT05187117
- Testing
- CAPABLE Family - Open Label Pilot, CAPABLE Family - Randomized Control Trial
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Psoriasis, Mycosis Fungoides
T Cell Repertoire Analysis of Immune Mediated Skin Diseases
This study is designed to identify the cells of the immune system that cause skin disease such as psoriasis and mycosis fungoides.
- Trial name
- NCT00368784
- Where
- United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Virtual Reality, Pediatric ALL
Virtual Reality in the Management of Pain in Pediatrics: a Multi-center Randomized Clinical Trial (RealPED)
The goal of this clinical trial is to test if the use of virtual reality glasses reduces the pain and anxiety that children feel when they perform a blood test.
- Conditions
- Virtual Reality, Pediatric ALL, Pain, Procedural
- Trial name
- RealPED (NCT05902585)
- Testing
- Virtual reality
- Where
- 6 sites in Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Acute Lymphoblastic Leukemia
Pharmacokinetics and Immunogenicity of the First Doses of PEG-Asparaginase -An ALLTogether Pilot Study
Acute lymphoblastic leukemia (ALL) is the most common malignant disease in childhood. Survival rates exceed 90% in children and 75% in adults (aged 18-45 years).
- Trial name
- NCT04843150
- Where
- 2 sites in Denmark
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Cognitive Deficits, Mild
Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin Combination
This randomized, double-blind, placebo-controlled trial will evaluate whether 12 weeks of supplementation with the probiotic Lactobacillus rhamnosus GG combined with colon-delivered riboflavin will improve cognitive performance…
- Trial name
- MENTOR (NCT07410052)
- Testing
- Experimental 1, Experimental 2
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Marasmus, Kwashiorkor
Mothers Understand And Can do it - Mid Upper Arm Circumference Screening for Malnutrition Performed by Mothers
PRIMARY OBJECTIVE : To determine whether mothers, given minimal group training, are capable of using a MUAC (mid-upper arm circumference) bracelet to screen their children for malnutrition and categorise them into one of three…
- Conditions
- Marasmus, Kwashiorkor, Malnutrition; Degree, Moderate, Malnutrition
- Trial name
- MUAC (NCT01790815)
- Where
- Niger
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alliance for International Medical Action
Cervix Cancer, Cervix Intraepithelial Neoplasia Grade 3
Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya
This study investigates the pharmacokinetics of Artesunate (AS) and dihydroartemisinin (DHA), the active metabolite of Artesunate, following intravaginal use at the dosing and frequency being studied for cervical precancer…
- Conditions
- Cervix Cancer, Cervix Intraepithelial Neoplasia Grade 3, Cervix; Intraepithelial Neoplasia, Grade I, Cervix; Intraepithelial Neoplasia, Grade II
- Trial name
- NCT06263582
- Testing
- Artesunate pessary, blood draws for pharmacokinetics of the study drug
- Where
- Kenya
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Hepatic Impairment
A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD2389
The purpose of this study is to examine the safety and tolerability of AZD2389 in participants with hepatic impairment and participants with normal hepatic function.
- Trial name
- CAMPOLINA (NCT06812780)
- Testing
- AZD2389
- Where
- 5 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
All
Amish/Mennonite Research Contact Registry
The purpose of this registry is to find members of the Plain Community who are interested in participating in future medical research studies.
- Trial name
- NCT02990572
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy, Adult ALL
Motion Capture as a Tool for the Assessment of Laparoscopic Performance
The goal of this study is to 1) identify motion capture variables that can be used to differentiate surgical experience level and 2) evaluate if these variables can be used in a surgical education setting to improve resident…
- Trial name
- NCT04646304
- Testing
- Objective Feedback (Motion Capture)
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Acute Myelocytic Leukemia, Acute Lymphocytic Leukemia
Studies on the Significance of CXCR4-CXCL12 on Leukemic Cells Passing Through"Marrow-Blood Barrier"
Bone marrow consists of a complex hematopoietic cellular component.When the blood progenitor cells differentiate to mature cells, they will exit unassisted to peripheral blood.
- Trial name
- NCT00155844
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Acute Lymphoid Leukemia, Acute Myeloid Leukemia in Children
Study of the Medullary Microenvironment in Acute Childhood Leukemia
Acute leukemia (AL) is the most common cancer in children. Despite the optimization of chemotherapy treatments and the development of supportive care, a certain number of LAs relapse and/or progress to death of the child.
- Trial name
- MILA (NCT05792007)
- Testing
- Biological sampling in patients, Biological sampling in control patients
- Where
- 3 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Leukemia
Genetic Study of Chronic Lymphocytic Leukemia Families
The goal of this research is to identify genes that may be related to the risk of developing CLL. Objectives: The objective of this study to investigate possible candidate susceptibility genes for familial chronic lymphocytic…
- Trial name
- NCT00503256
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Acute Lymphoblastic Leukemia
Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Eukaemia During Therapy With L - Asparaginase.
Haematological malignancies constitute the most common neoplastic disease in child population, with acute leukemia occupying the number one spot with a percentage of 32.8%.
- Trial name
- NCT04364451
- Testing
- Correlation of Polymorphisms of Lipoprotein Lipase (LpL) and Apolipoprotein E (Apo E) With Lipid Profile of Children With Acute Lymphoblastic Leukaemia During Therapy With L - Asparaginase
- Where
- Greece
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Pediatric ALL
Assessing Neurophysiological and Cognitive Function in School Children
This trial will investigate the feasibility of implementing our novel assessment battery in a neurodiverse pediatric population.
- Trial name
- WIS (NCT06209528)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Life University
Advanced Malignant Solid Neoplasm, Caregiver
Frequency of Cachexia in Ambulatory Cancer Patients and Psychological Burden in Patients and Their Primary Caregivers
This trial studies the frequency of cachexia in ambulatory cancer patients and the psychological burden in patients and their primary caregivers who are referred to an outpatient supportive care clinic.
- Conditions
- Advanced Malignant Solid Neoplasm, Caregiver, Metastatic Malignant Solid Neoplasm, Recurrent Leukemia
- Trial name
- NCT04090619
- Testing
- Questionnaire Administration
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Asthma
University of Wisconsin Severe Asthma Research Program III
The overall goal of this proposal is to better understand the basis of structural airway changes in severe asthma and how asthma exacerbations may contribute to their progression over time.
- Trial name
- NCT01760915
- Testing
- NC100182 Hyperpolarized 3He
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison