Clinical trials: MARS
Current Smoker, Tobacco Smoking
Project MARS: Mobile-Assistance for Regulating Smoking
This study aims to investigate approaches to capitalize on states of vulnerability and receptivity to deliver real-time self-regulation prompts among smokers.
- Trial name
- MARS (NCT04376489)
- Testing
- Messages recommending low effort strategies (participants experiencing negative affect & cigarettes are available), Messages recommending low effort strategies (participants not experiencing negative affect & cigarettes are available), Messages recommending low effort strategies (participants experiencing negative affect & cigarettes are not available)
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Utah
Muscular Atrophy
Biological and Functional Markers for Precision Astronautical Biomedicine
In the current study the investigators will study early biomarkers of human degradation. In 10-day horizontal bed rest the investigators will enroll 10 healthy male subjects (18-30years, BMI 20-28kg/m2).
- Trial name
- MARS-PRE (NCT04081467)
- Testing
- Bed rest
- Where
- Slovenia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper
Obesity
Microvascular Flow Assessment Repeatability Study: The MARS Study
The purpose of this study is to test a method of imaging (taking a picture) of the abdomen (belly), neck, thigh and calf (lower leg) areas of the body, using ultrasound along with a drug which makes the pictures look clearer.
- Trial name
- MARS (NCT01242020)
- Testing
- Perflutren Lipid Microsphere Injectable Suspension
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Polyuria-polydipsia Syndrome, Arginine Vasopressin Deficiency
Mannitol-induced Release of Copeptin in Healthy Adults and Patients With Polyuria-Polydipsia Syndrome (MARS Study)
The aims of this study are to investigate whether mannitol stimulates copeptin (part 1: proof-of-concept) and whether the copeptin levels upon mannitol infusion differ in primary polydipsia and arginine vasopressin deficiency…
- Conditions
- Polyuria-polydipsia Syndrome, Arginine Vasopressin Deficiency, Primary Polydipsia
- Trial name
- MARS (NCT06542198)
- Testing
- Mannitol Infusion (blinded), Mannitol Infusion (open label)
- Where
- Switzerland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Stroke
Monitoring Arm Recovery After Stroke (MARS)
People who have a stroke often find it hard to do the things they did before. This can be caused by problems with arm movement. One in five people do not get any arm movement back after a stroke.
- Trial name
- MARS (NCT07016295)
- Testing
- Biomechanical analysis of arm movement, Pose estimation of arm movement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Placenta Diseases
MARS: Magnetic Resonance Study: A Novel Assessment of Placental Function
The objective of this study is to evaluate functional MRI as a tool to study placental transfer of oxygen and nutrients during the third trimester of pregnancy in obese women, women with pregestational diabetes and healthy low…
- Trial name
- NCT03764878
- Testing
- functional MRI
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Sleep, Alertness
Operational Evaluation of a Photic Countermeasure to Improve Alertness, Performance, and Mood During Nightshift Work on a 105-day Simulated Human Exploration Mission to Mars
The success of human expedition missions critically depend on the ability of the crew to be alert and maintain high levels of cognitive function while operating complex, technical equipment.
- Conditions
- Sleep, Alertness, Fatigue
- Trial name
- Mars 105 (NCT01169233)
- Testing
- Bright Light Box
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Instructional Virtual Realities, Weightlessness Simulation
VR-MARS Virtual Reality, Medical Assistance and Rescue for Space
VRMARS is a medical simulation study in microgravity. Healthy volunteers (n=18) test in microgravity the functionnality of an augmented reality headset in which a medical assistance is displayed.
- Conditions
- Instructional Virtual Realities, Weightlessness Simulation, Space Simulation, Patient Simulation
- Trial name
- VR-MARS (NCT06144658)
- Testing
- Augmented Reality Headset / Hololens 2 or Varjo XR3
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier de Bretagne Sud
Extraterrestrial Habitation Systems, Lunar Surface Habitation
A Multiphase Operational and Environmental Assessment of Lunar Surface Habitation, Lunar Gateway Transit Systems, and Acceleration Pathways for Sustained Human Habitation of the Martian Surface
This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the…
- Conditions
- Extraterrestrial Habitation Systems, Lunar Surface Habitation, Lunar Water-Ice Resource Assessment, In-Situ Resource Utilization (ISRU)
- Trial name
- LUMEN-HAB (NCT07546461)
- Testing
- Habitat Systems Evaluation, Water-Ice Resource Utilization Assessment, EVA and Mobility Operations
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Oxidative Stress
Monitoring Antioxidant/Redox Status at Concordia (MARS-C)
The European Space Agency (ESA) runs a research centre in Antarctica as an earth-based model for long duration deep-space missions.
- Trial name
- MARS-C (NCT04197193)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Acute Pain, Emergencies
Machine Learning for Risk Stratification in the Emergency Department (MARS-ED)
Rationale Identifying emergency department (ED) patients at high and low risk shortly after admission could help decision-making regarding patient care.
- Trial name
- MARS-ED (NCT05497830)
- Testing
- RISK-INDEX
- Where
- Netherlands
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cognitive Function
Mars Flavanol Exercise and Cognitive Function Study
This is a randomized controlled trial to test the impact of a flavonol containing food product and aerobic exercise on cognitive function and brain structure.
- Trial name
- NCT01180127
- Testing
- Flavanol containing food product, Aerobic training, Food product lacking flavanol
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute