Clinical trials: MINOCA
MINOCA
Myocardial Infarction With Non-obstructive Coronary Arteries: Italian Study
Acute coronary syndromes have been extensively studied in recent decades, focusing mainly on myocardial infarctions with obstructive coronary artery disease and early revascularisation strategies.
- Trial name
- MINOCA-IT (NCT06511817)
- Testing
- No intervention will be performed
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Myocardial Infarction With Non-obstructive Coronary Arteries, Grow Stimulation Expressed Gene 2
Rapid Identification of MINOCA Based on Novel Biomarkers
Among the patients diagnosed as acute myocardial infarction by coronary angiography, 5%-25% of the patients did not find coronary artery obstructive lesions. These patients do not need PCI.
- Conditions
- Myocardial Infarction With Non-obstructive Coronary Arteries, Grow Stimulation Expressed Gene 2, Copeptin, Identification
- Trial name
- NCT04974320
- Testing
- blood biomarkers
- Where
- China
- Volunteers
- 2,616 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Coronary Syndrome, Myocardial Infarction
Cardiac Structure, Function, and Clinical Manifestations in MINOCA
The purpose of this study is to improve the differential diagnosis and clinical outcomes of acute coronary syndrome with non-obstructive coronary arteries, to investigate the relationship between the structural and functional…
- Trial name
- MINOCA (NCT03572023)
- Testing
- Integrative characterization of MINOCA patients, Characterization of MI patients with coronary obstruction
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Spontaneous Coronary Artery Dissection, SCAD
Canadian SCAD Study
Natural history multicenter, prospective, observational registry with 10-year follow-up
- Conditions
- Spontaneous Coronary Artery Dissection, SCAD, Fibromuscular Dysplasia
- Trial name
- NCT04906356
- Testing
- Genetic sub-study
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- Cardiology Research UBC
Acute Myocardial Infarction, Non-Obstructive Coronary Atherosclerosis
Myocardial Infarction With Non-Obstructive Coronary Arteries in the Greek Population
The MINOCA-GR registry will be the first nationwide study aiming to obtain data regarding prevalence, demographics, clinical profile, previous anginal status, presence of cardiovascular risk factors, management and outcomes in…
- Conditions
- Acute Myocardial Infarction, Non-Obstructive Coronary Atherosclerosis, Ischemic Heart Disease, Angina Pectoris
- Trial name
- MINOCA-GR (NCT04186676)
- Testing
- MINOCA registry, CCTA Phenotypes
- Where
- 3 sites in Greece
- Volunteers
- 60 people
- Sponsor
- AHEPA University Hospital
Acute Coronary Syndromes (ACS), Chronic Coronary Syndrome
Starring Optical Coherence Tomography During Percutaneous Coronary Intervention Guidance
The starring optical coherence tomography during percutaneous coronary intervention guidance (OCT-AGEM) registry aims to evaluate the clinical impact of intra-procedural optical coherence tomography (OCT) in coronary…
- Conditions
- Acute Coronary Syndromes (ACS), Chronic Coronary Syndrome, MINOCA, INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
- Trial name
- OCT-AGEM (NCT07182799)
- Testing
- Plaque vulnerability assessment, Stent implantation optimization
- Where
- Italy
- Volunteers
- 3,200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Myocardial Infarction, Gender
Barts-MINOCA Registry
The last 15 years the introduction of primary angioplasty has radically improved outcomes for acute myocardial infarction (AMI).
- Conditions
- Myocardial Infarction, Gender, Coronary Microvascular Disease
- Trial name
- NCT04440761
- Testing
- Observation only
- Where
- United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- Queen Mary University of London
Myocardial Infarction With Non-obstructive Coronary Arteries
Randomized Evaluation of Beta Blocker and ACEI/ARB Treatment in MINOCA Patients - MINOCA-BAT
Myocardial infarction with non-obstructive coronary arteries" (MINOCA) occurs in 5-10% of all patients with AMI. There are neither any randomized clinical trials in MINOCA patients evaluating effects of secondary preventive…
- Trial name
- MINOCA-BAT (NCT03686696)
- Testing
- Beta blocker, ACEI, ARB
- Where
- 32 sites in Australia, New Zealand and 3 more
- Volunteers
- 198 people
- Sponsor
- Uppsala University
Myocardial Infarction With Non-Obstructive Coronary Artery, Ischemia With Non-Obstructive Coronary Artery
Intracoronary Provocative Test With Acetylcholine in Patients With INOCA and MINOCA
Coronary vasomotor disorders, occurring both at microvascular and epicardial level, have been demonstrated as responsible for myocardial ischemia in a sizeable group of patients undergoing coronary angiography (CAG), with…
- Trial name
- Provoke (NCT05714319)
- Testing
- Data collection, Clinical follow-up
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
MINOCA
Plaque Burden and Ischemia in MINOCA
The goal of this clinical trial is to assess coronary artery plaque burden, perivascular inflammation and extent of myocardial ischemia in patients presenting with acute myocardial infarction and non-obstructive coronary artery…
- Trial name
- NCT05681858
- Testing
- CT coronary angiography and [12N] NH3 PET-MR
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Bergen
Platelet Indices, White Blood Cell
Beyond Platelet Indices, WBC-to-MPV Ratio in Myocardial Infarction With Non-Obstructive Coronary Arteries (MINOCA) Correlate With Short-Term Rather Than In-Hospital Outcomes
This study aims to evaluate the role of platelet indices and the [White blood cell (WBC) /mean platelet volume (MPV)] ratio in correlation with angiographic profiles of patients diagnosed with myocardial infarction with…
- Conditions
- Platelet Indices, White Blood Cell, Mean Platelet Volume, Myocardial Infarction
- Trial name
- NCT07076732
- Testing
- Coronary Angiography, SYNTAX Score
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University
MINOCA
Prognostic Significance of CMR-Confirmed Infarct in MINOCA Patients from Sweden and Australia
Myocardial Infarction (MI) with Non-Obstructive Coronary Arteries (MINOCA), occurring in 6-8% of MIs, refers to patients who experience a heart attack without obstructive coronary artery disease (CAD) or significant…
- Trial name
- SWEET (NCT06889428)
- Testing
- CMR
- Where
- Australia
- Volunteers
- 1,000 people
- Sponsor
- University of Adelaide