Clinical trials: MINS
Head and Neck Surgery, Maxillofacial Surgery
Impact of Nociception Level (NOL)-Guided Remifentanil Infusion on Intraoperative Arterial Pressure and Vasopressor Necessity
The aim of this study is to determine if Nociception Level (NOL)-guided Remifentanil analgesia, combined with Entropy-guided Propofol anesthesia, has a significant beneficial effect on the incidence of intraoperative hypotension…
- Trial name
- NCT04963036
- Testing
- Entropy and NOL-Guided Goal Directed Anesthesia, Standard of Care Group (Entropy and blinded NOL)
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Frailty, Esmolol
Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail Patients
This topic will focus on the following questions: 1. Part one: To clarify the relationship between preoperative frailty and myocardial injury (cTnT ≥0.03) after non-cardiac surgery in elderly patients; To further explore the…
- Conditions
- Frailty, Esmolol, Myocardial Injury
- Trial name
- NCT05635877
- Testing
- Esmolol
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Yongtao Sun
Perioperative Care
Validation of B-type Natriuretic Peptide With N-terminal Pro B-type Natriuretic Peptide in Perioperative Risk Assessment
This is a single-centre, prospective study to determine the correlation and comparative thresholds between N-terminal pro-brain natriuretic peptide (NT ProBNP, Roche) and brain natriuretic peptide (BNP, Abbott) tests.
- Trial name
- NCT05352698
- Testing
- NT ProBNP (Roche)
- Where
- Canada
- Volunteers
- 466 people
- Sponsor
- Jordan Leitch
Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance
Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery
The goal of this clinical trial is to learn whether physicians can associate evidence of myocardial injury after surgery with findings obtained from submaximal cardiopulmonary exercise testing.
- Conditions
- Myocardial Injury After Non-cardiac Surgery, Submaximal Exercise Performance, Preoperative Period
- Trial name
- EnhanceMINS (NCT06474754)
- Testing
- High-sensitivity troponin, serum, Submaximal Cardiopulmonary Exercise Testing, Duke Activity Status Index
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Myocardial Ischemia, Diabetes Complication
Evaluation of Perioperative Myocardial Injury in Patients Undergoing Below-Knee Lower Extremity Surgery
The aim of this observational study was to detect myocardial damage by monitoring high-sensitive troponin I levels in patients undergoing below-knee extremity surgery with peripheral nerve block.
- Trial name
- NCT07241572
- Testing
- high sensitive Troponin I
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Myocardial Injury After Noncardiac Surgery (MINS)
Myocardial Injury After Transurethral Resection
This prospective observational study aims to determine the incidence of myocardial injury after noncardiac surgery (MINS) in adult patients undergoing elective transurethral resection of the prostate (TURP) or transurethral…
- Trial name
- TUR-MINS (NCT07900035)
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people
- Sponsor
- Haseki Training and Research Hospital
Myocardial Ischemia, Myocardial Injury
Perioperative Myocardial Ischemia: Troponin Monitoring,Cost-effectiveness, Insights Into Pathophysiology
Background: Despite preoperative screening, technical improvements and increased patient monitoring, perioperative myocardial infarction (PMI) remains the first cause of morbidity and mortality within 30 days after surgery.
- Conditions
- Myocardial Ischemia, Myocardial Injury, Morality
- Trial name
- PMI (NCT03438448)
- Testing
- High sensitive Troponin T monitoring
- Where
- Spain
- Volunteers
- 1,510 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Risk
Remembering Risk Using Visual Risk Display of MINS to Obtain Informed Consent to Undergo Elective Surgery
Disclosure of anticipated risks to individuals considering undergoing an elective operative procedure is an important aspect of informed consent process.
- Trial name
- NCT05098535
- Testing
- Visual Aid, Scripted Risk Discussion
- Where
- Canada
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Queen's University
Myocardial Injury After Noncardiac Surgery (MINS)
Management of Myocardial Injury After Noncardiac Surgery Trial
Patients who have myocardial injury after noncardiac surgery are at a higher risk of dying than those who do not. One in 10 patients with myocardial injury will die within 30 days of surgery.
- Trial name
- MANAGE (NCT01661101)
- Testing
- Dabigatran, Omeprazole
- Where
- 82 sites in United States, Argentina and 17 more
- Volunteers
- 1,754 people
- Sponsor
- Population Health Research Institute
MINS
PeriOperative Medicine - Metabolic Inflexibility as a Mechanism for Myocardial Injury After Non-Cardiac Surgery
The goal of this observational study is to learn whether metabolic inflexibility, which means reduced ability of the body to switch between using fats and sugars for energy, is associated with myocardial injury after non-cardiac…
- Trial name
- POM-MIMICS (NCT07694453)
- Testing
- Pre-operative Metabolic Inflexibility
- Volunteers
- 300 people
- Sponsor
- University College, London
Myocardial Infarction
Predicting Myocardial Infarction After Abdominal Surgery: Clinical Scores & Biomarkers
All patients undergoing non-cardiac surgery who met the inclusion criteria underwent a preoperative evaluation using specific assessment tools.
- Trial name
- NCT06767943
- Testing
- 12-lead electrocardiography
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Vascular Surgery
Association of PeriOPerative Aspirin-ResisTance and CardioVascular Outcome
The aim of our study is to investigate the association between perioperative aspirin resistance and Myocardial Injury after Non-cardiac Surgery (MINS) in patients undergoing vascular surgery.
- Trial name
- POPART-CVO (NCT04053894)
- Where
- Germany
- Volunteers
- 220 people
- Sponsor
- University Hospital Heidelberg
Myocardial Injury After Non-cardiac Surgery
Preoperative BNP and MINS in AAA Open Repair
The aim of this study was to investigate whether preoperative B-type natriuretic peptides serves as an independent predictor of myocardial injury after non-cardiac surgery (MINS) in abdominal aortic aneurysm open repair.
- Trial name
- NCT06088641
- Testing
- preoperative BNP value
- Where
- South Korea
- Volunteers
- 198 people
- Sponsor
- Gangnam Severance Hospital
Postoperative Cardiac Complication
VitamIn and oXygen Interventions and Cardiovascular Events
This study examines the risks and benefits of antioxidants and normal versus high inspiratory oxygen fraction during anaesthesia.
- Trial name
- VIXIE (NCT03494387)
- Testing
- Oxygen, Antioxidants
- Where
- 4 sites in Denmark
- Volunteers
- 600 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Breast Cancer, Myocardial Injury After Noncardiac Surgery (MINS)
Impact of Propranolol Strategies on Myocardial Injury After Breast Cancer Surgery
This study aims to evaluate the impact of using propranolol, a non-selective beta-blocker, on preventing myocardial injury after non-cardiac surgery (MINS) in breast cancer patients who also have hypertension or angina.
- Trial name
- B-BIT (NCT07583134)
- Testing
- propranolol, Usual Care
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Chang-Ik Yoon
Hip Fractures
Hypobaric Lateral Spinal Anesthesia Versus General Anesthesia for the Hip Fracture Surgery
Hip fracture is a frequent pathology, involving elderly patients with many co-morbidities ; therefore, post-operative morbidity and mortality is high.
- Trial name
- RACHYP (NCT03373864)
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Hospices Civils de Lyon
Perioperative/Postoperative Complications, Outcome
Evaluation of BIomarkers for POstoperative Complications in Non-cardiac Surgery Patients
Aim of this study is to evaluate whether the periopertive course is able to predict postoperative complications. Several approaches will be choosed to optimize perioperative risk stratification predicting postoperative…
- Trial name
- NCT03765372
- Where
- Germany
- Volunteers
- 1,598 people
- Sponsor
- Technical University of Munich
Risk
Remembering Risk: Using Visual Risk Display of MINS to Obtain Informed Consent to Undergo Elective Surgery
Disclosure of anticipated risks to individuals considering undergoing an operative procedure is an important aspect of informed consent process.
- Trial name
- NCT04247841
- Testing
- Visual Aid, Scripted Risk Discussion
- Where
- Canada
- Volunteers
- 456 people
- Sponsor
- Dr. Michael McMullen
MYOCARD INFARCTUS, Non Cardiac Surgery
Myocardial Injury After Noncardiac Surgery (MINS) in Lumbar Surgery Patients
The aim of this study is to evaluate the incidence of myocardial injury after noncardiac surgery (MINS) in patients undergoing lumbar surgery, and to investigate the associated risk factors.
- Conditions
- MYOCARD INFARCTUS, Non Cardiac Surgery, Lumbar Surgery, Anesthesia
- Trial name
- NCT07081009
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
MYOCARD INFARCTUS, Non Cardiac Surgery
Myocardial Injury After Noncardiac Surgery (MINS) in Patients Undergoing Knee and Hip Arthroplasty
The aim of this study is to determine the incidence of myocardial injury after noncardiac surgery (MINS) in patients undergoing elective total knee or hip arthroplasty, and to identify the demographic, clinical, laboratory, and…
- Conditions
- MYOCARD INFARCTUS, Non Cardiac Surgery, ARTHROPLASTY, REPLACEMENT; ANESTHESIA
- Trial name
- MINS (NCT07098468)
- Where
- Turkey (Türkiye)
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent