Clinical trials: Macular Thickness
Cataract
No Drop Post-Op Cataract Surgery
This study evaluates the effect of Intraocular Phenylephrine/Ketorolac Infusion on Retinal Thickness and Macular Edema in Cataract Surgery.
- Trial name
- NCT03864133
- Testing
- Omidria
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Retinopathy, Clinically Significant Macular Edema
Reduction of Foveal Sensitivity in Eyes With Diabetic Macular Edema
Clinically significant macular edema (CSME) is a thickening of the macula associated with the risk of visual loss, which increases its centre is involved.
- Trial name
- NCT01824862
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Juarez de Mexico
Macular Holes
Full-Thickness Macular Hole Surgery: A Comparison of Ten Techniques
This study compares ten modern vitreoretinal surgical techniques for full-thickness macular hole repair. Participants will be randomly assigned to one of the surgical approaches during pars plana vitrectomy, using stratified…
- Trial name
- FTMH-10 (NCT07606404)
- Testing
- Pars Plana Vitrectomy (PPV)-Based Macular Hole Surgery, Autologous Platelet-Rich Plasma (PRP), Human Amniotic Membrane (hAM) Graft
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Kazakh Eye Research Institute
Macular Holes
Inverted ILM Repositioning as Treatment for Full Thickness Macular Holes
The purpose of this study is to evaluate the efficacy and safety of surgical treatment of FTMH using an inverted ILM repositioning to improve anatomical and functional outcomes in patients with a macular hole.
- Trial name
- NCT01228188
- Testing
- Inverted ILM Repositioning
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Military Institute od Medicine National Research Institute
Diabetic Macular Edema, Diabetic Retinopathy
Early Anatomical, Physiological, and Clinical Changes in Diabetic Macular Edema After Intravitreal Aflibercept Injection
This is a one month pre post intervention study. Subjects with diabetic macular edema were given intravitreal anti VEGF (Aflibercept) injection.
- Conditions
- Diabetic Macular Edema, Diabetic Retinopathy, Clinically Significant Macular Edema
- Trial name
- NCT03453281
- Testing
- Aflibercept Injection [Eylea]
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Universitas Indonesia
Age Related Cataracts, Cystoid Macular Edema
Evaluation of Central Macular Thickness in Femtosecond Laser-assisted Cataract Surgery
The investigational device is an approved femtosecond laser (FSL) device with an integrated imaging system to perform certain steps of the cataract procedure.
- Trial name
- FLAME (NCT03465124)
- Testing
- Femtosecond Laser, Manual Cataract Surgery
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Diabetic Retinopathy
A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin)
This study will provide preliminary data on the dose and dose interval related effects of intravitreally administered Avastin on retinal thickness and visual acuity in subjects with Diabetic Macular Edema (DME) to aid in planning…
- Trial name
- Bevacizumab (NCT00336323)
- Testing
- Laser Photocoagulation, Bevacizumab
- Where
- 34 sites in United States
- Volunteers
- 121 people
- Sponsor
- Jaeb Center for Health Research
Diabete Type 2, Cataract
Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.
The investigators aim in this study to investigate the effect of intravitreal triamcinolone acetonide injection on the development of macular edema and the progression of diabetic retinopathy.
- Conditions
- Diabete Type 2, Cataract, Triamcinolone Acetonide, Intravitreal Injection
- Trial name
- NCT05413330
- Testing
- Triamcinolone Acetonide
- Where
- Syria
- Volunteers
- 73 people
- Sponsor
- Damascus University
Diabetic Retinopathy, Macular Edema
Visual Function, Center Point Thickness and Macular Volume After Photocoagulation
The purpose of this study is to correlate changes of visual function three weeks after photocoagulation for macular edema, with changes of center point thickness and macular volume.
- Trial name
- NCT00906659
- Where
- Mexico
- Volunteers
- 89 people
- Sponsor
- Hospital Juarez de Mexico
Exudative Age Related Macular Degeneration
The Spectralis-Cirrus Study
Retinal thickness measurement is one of the most important examinations in the follow up of exudative age-related macular degeneration.
- Trial name
- NCT00927303
- Testing
- Cirrus-Spectralis, Spectralis-Cirrus
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- The Ludwig Boltzmann Institute of Retinology and Biomicroscopic Laser Surgery
Diabetic Retinopathy, Macular Edema
Topic Antiinflammatory Therapy Added to Selective Photocoagulation in Macular Edema
The purpose of this study is to determine the efficacy of ocular topic antiinflammatory therapy (sodic nepafenac at 0.1% or ketorolac at 0.5%) to treat center point thickness secondary to selective photocoagulation in diabetics…
- Trial name
- NCT00900887
- Testing
- Ketorolac, Nepafenac, Polietilenglicol 400, propilenglicol
- Where
- Mexico
- Volunteers
- 84 people
- Sponsor
- Hospital Juarez de Mexico
Macular Holes, High Myopia
Effects of Macular Buckle Versus Vitrectomy on Macular Hole and Macular Detachment in Highly Myopic Eyes
Full-thickness macular Hole associated with macular detachment is a one of the maculopathies of high myopia. There is controversy in the primary treatment for this situation.
- Conditions
- Macular Holes, High Myopia, Macular Detachment
- Trial name
- NCT03433547
- Testing
- Buckle, Vitrectomy, Limbal paracentesis
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Retinal Pathology
Prospective Comparison of Cirrus Versus Stratus Ocular Coherence Tomography for Different Retinal Pathology.
Ocular Coherence Tomography (OCT) is a non-invasive ophthalmologic test that uses reflected, unheated, non-concentrated visible light in order to scan and provide a 2-dimensional topographic analysis of the retina and optic…
- Trial name
- NCT00731458
- Testing
- Optical coherance tomography ( Cirrus; Stratus)
- Volunteers
- 60 people
- Sponsor
- University of Chicago
Asherman Syndrome
Pre-clinical Endometrial Tissular Renovation Study
The endometrium is a tissue with high capacity of renewal ("self-renewal"). This process is regulated by stem cells. Recent studies have shown that bone marrow-derived stem cells (BMDSCs) contribute to tissues and organs…
- Trial name
- PreENTIRE (NCT03665649)
- Testing
- CD133+ cells isolation
- Where
- Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Igenomix
Full Thickness Macular Hole
Protocol for RCT of Posturing in Phacovitrectomy for Full Thickness Macular Hole (FTMH)
The purpose of this study is to determine the effect of postoperative posturing on the outcome of macular hole surgery. Current practice is divided; some individuals are advised to posture face-down for 10 days and others are…
- Trial name
- NCT01020760
- Testing
- Face down posture
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- NHS Greater Glasgow and Clyde