Clinical trials: Magnetic Resonance Imaging (MRI)
Ankylosing Spondylitis
Etanercept (Enbrel) in Ankylosing Spondylitis
The study has the aim to investigate the efficacy and safety of etanercept in patients with active ankylosing spondylitis (AS) over 520 weeks.
- Trial name
- Enbrel_AS-2 (NCT01289743)
- Testing
- Etanercept
- Where
- 2 sites in Germany
- Volunteers
- 24 people
- Sponsor
- Charite University, Berlin, Germany
Positron Emission Tomography-Magnetic Resonance (PET-MR)
Enhancing SUV Accuracy of PET/MR for Clinical Trial Qualification
Standardized Uptake Values (SUVs), normalized activity concentration, measured using PET/MR have inaccuracies ≥ 20% which exceeds National Cancer Institute / American College of Radiology Imaging Network (NCI/ACRIN), Radiological…
- Trial name
- NCT03603925
- Testing
- Positron Emission Test / Magnetic Resonance (PET/MR), Positron Emission Test / Computed Tomography (PET/CT)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Case Comprehensive Cancer Center
Hypoxic Ischemic Encephalopathy
Whole Body Cooling Using Phase Changing Material
A prospective randomized control trial to examine safety and effectiveness of whole body cooling to a rectal temperature of 33.5 C using phase changing material in neonatal encephalopathy.
- Trial name
- NCT01138176
- Testing
- Cooling
- Where
- India
- Volunteers
- 35 people
- Sponsor
- Robertson, Nicola, M.D.
Breast Cancer
Assessing Breast Density's Value in Imaging - A Comparative Effectiveness Study
This Breast Cancer Surveillance Consortium (BCSC) ADVANCE study is a large, observational pragmatic comparative effectiveness research study using high-quality, prospectively collected data from BCSC registries to generate…
- Trial name
- BCSC-ADVANCE (NCT02980848)
- Testing
- Screening digital mammography, Screening digital breast tomosynthesis, Screening breast magnetic resonance imaging
- Where
- 7 sites in United States
- Volunteers
- 1,341,172 people
- Sponsor
- University of California, Davis
Healthy
Use of Transcranial Magnetic Stimulation (TMS) and Magnetic Resonance Imaging (MRI) to Study Visual Attention
The purpose of this study is to learn more about how the brain allows people to focus on important objects and filter out unimportant ones when looking at visual images.
- Trial name
- NCT00006285
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Acute Stroke
CT or MRI in Work up for i.v. Thrombolysis: a Single-centre Study
Acute stroke occurs in approximately 13.000 persons every year in Denmark, 10 - 15 % now receives intervenous thrombolytic therapy, which remains the most important acute treatment in ischaemic stroke.
- Trial name
- NCT02780843
- Testing
- Computerized Tomography, Magnetic Resonance Imaging
- Where
- Denmark
- Volunteers
- 499 people
- Sponsor
- Bispebjerg Hospital
Focus of Study is MRI
Non-Enhanced Magnetic Resonance Angiography With the t-SLIP Technique
The purpose of the study is to create MR images using an investigative technique called pulse sequences with new computer software programs. The sequence will allow us to image vessels without injecting contrast agents.
- Trial name
- MRAtSLIP (NCT02032940)
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Miami Cardiac and Vascular Institute
Heart Transplant Rejection
Cardiac Magnetic Resonance Imaging (CMRI) for Detection of Cardiac Transplant Rejection
To find a non-invasive alternative (with using cardiac MRI) to invasive endomyocardial biopsies for serial detection (EMB) and follow-up of cellular rejection in heart transplant in childhood.
- Trial name
- NCT01136135
- Testing
- CARDIAC MRI
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
Tracking Inflammatory Cells Using Superparamagnetic Particles of Iron Oxide (SPIO) and Magnetic Resonance Imaging (MRI)
Treatment of a wide range of diseases using stem cells and other types of cell appears promising. Following administration of cells it is often not clear where exactly the cells have gone and how many of them have reached the…
- Trial name
- NCT01169935
- Testing
- Administration of intra-dermal Endorem, Mantoux test, Autologous Endorem-labelled mononuclear cells
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Breast Neoplasms, Cardiovascular Diseases
Acute and Long-term Cardiovascular Toxicity After Modern Radiotherapy for Breast Cancer
In Europe, breast cancer is by far the most common form of cancer diagnosed in women today, accounting for 29% of all cases. The 5-year survival rate is approximately 90%.
- Trial name
- NCT02541435
- Where
- 2 sites in Norway
- Volunteers
- 1,600 people
- Sponsor
- St. Olavs Hospital
Invasive Breast Cancer
Adding Preoperative Radiotherapy Based on Early Treatment Response in Breast Cancer
RAPID-NeoBC is a prospective, multicentre, response-adapted study with a randomized component for adults with operable, nonmetastatic invasive breast cancer receiving guideline-recommended neoadjuvant systemic therapy.
- Trial name
- RAPID-NeoBC (NCT07892508)
- Testing
- Response-adapted preoperative radiotherapy, Guideline-recommended neoadjuvant systemic therapy, Serial contrast-enhanced breast MRI and breast-specific gamma imaging
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Osteoarthritis, Knee
MR Imaging of Knee Osteoarthritis and Acute Knee Injuries
The purpose of this study is to use better magnetic resonance imaging (MRI) techniques to examine the knee and the bony and soft tissue changes so as to better predict the progression of osteoarthritis and acute knee injuries.
- Trial name
- NCT00504114
- Testing
- ACL Reconstruction Surgery, Cartilage Resurfacing Surgery, Total Knee Replacement
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Schizophrenia, Transcranial Magnetic Stimulation
Personalized iTBS in Real-World Clinical Settings for Schizophrenia
This study is designed to determine whether neuronavigation-guided, personalized Intermittent Theta-Burst Stimulation (iTBS) can produce clinically benefits for patients with schizophrenia when delivered in real-world treatment…
- Trial name
- EPSREAL-SC (NCT07176468)
- Testing
- Neuronavigation-guided individualized iTBS
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Heart Failure
Age Gender Left Ventricular Mass and Cardiac Troponin T
The purpose of this study is to determine the influence of functional or anatomic cardiac parameters, age and gender on high sensitivity cTnT (TnThs) levels in healthy individuals.
- Trial name
- NCT01100710
- Where
- Germany
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Multiple Sclerosis
Correlation Between PET and Advanced MRI in Multiple Sclerosis
Traditional Magnetic Resonance Imaging (MRI) in Multiple Sclerosis (MS) has enabled clinicians to measure disease activity but there are inherent limitations.
- Trial name
- NCT02869360
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Magnetic Resonance Imaging, Vascular Complications
Qualitative and Quantitative Evaluation of Vascular Flows of Radial, Ulnar and Interdigital Arterial Trees Under Normal and Pathological Conditions by 3 Tesla MRI
Allotransplants of vascularized composite tissues are subject to chronic vascular rejection, which can lead to graft loss. Currently, no imaging technique allows a reproducible quantitative exploration of the arterial trees of…
- Conditions
- Magnetic Resonance Imaging, Vascular Complications, Transplantation, Radial Artery
- Trial name
- FLOWHAND (NCT04257747)
- Testing
- MRI acquisitions, Doppler ultrasound procedure
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Renal Tumor, Kidney Neoplasm
An MRI-Based Study of Intelligent Pathological Subtyping and Grading of Renal Tumors
This retrospective + prospective, non-interventional study aims to develop and evaluate artificial intelligence methods for the detection, pathological subtyping, and histological grading of renal tumors using magnetic resonance…
- Trial name
- NCT07743749
- Testing
- MRI-Based Artificial Intelligence Analysis
- Where
- China
- Volunteers
- 900 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Cocaine Dependence
Neuropsychological Rehabilitation on Cocaine/Crack Dependents
Cocaine/Crack Dependence has been associated with neuropsychological impairments mainly in executive functions and decision-making, which are predominantly managed by the prefrontal cortex (PFC) in the brain.
- Trial name
- NCT01914835
- Testing
- Motivational Chess
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo General Hospital
Insomnia, Cognitive Impairment
RESET-BRAIN: REhabilitation of SleEp and CogniTive Impairment in BReast Cancer Survivors Using an App-based Intervention
The goal of the study is to investigate whether treating insomnia using app-based cognitive behavioral therapy for insomnia (CBT-I) can improve cognitive impairment in breast cancer survivors compared to an active control group…
- Conditions
- Insomnia, Cognitive Impairment, Breast Cancer
- Trial name
- RESET-BRAIN (NCT06553235)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep hygiene education
- Where
- Denmark
- Volunteers
- 84 people
- Sponsor
- Aarhus University Hospital
Diabetes Mellitus, Type 2, Nicotine Dependence, Cigarettes
Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients
Diabetes has become an increasingly serious global health issue. In 2024, approximately 537 million adults were living with diabetes, and this number is projected to rise to 783 million by 2045, representing a 46% increase.
- Trial name
- NCT06924697
- Testing
- Application of GLP-1RAs drugs, DPP-4i group
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Shanghai East Hospital
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