Clinical trials: Magnetism
Rectal Cancer, Head and Neck Cancer
Feasibility of Online MR-guided Radiotherapy on a 1.5T MR-Linac
This study investigates the feasibility of imaging and treatment on a novel 1.5 T MR-Linac radiotherapy hybrid device.
- Conditions
- Rectal Cancer, Head and Neck Cancer, Liver Cancer, Breast Cancer
- Trial name
- NCT04172753
- Testing
- Radiotherapy on the MR-Linac, Imaging on the MR Linac
- Where
- Germany
- Volunteers
- 472 people
- Sponsor
- University Hospital Tuebingen
Epilepsy
Herpes Virus-6 and Epilepsy
This study will explore whether the human herpes virus-6 is associated with epileptic seizures. The virus may be involved in brain scarring, called mesial temporal sclerosis, which is seen in some epilepsy patients.
- Trial name
- NCT00085683
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Autism
Brain Plasticity of Autism in Response to Early Behavioral Intervention: A Multimodal MRI Study
Autism is a well-recognized neurodevelopmental disorder severely affecting the health of children. While the unclear neurobiological basis of autism and the lack of effective medication, the most commonly used approach for…
- Trial name
- NCT02807766
- Testing
- Behavior modification, Behavior modification and sensory integration training, Behavior modification and applied behavioral analysis
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET
FAPI PET/CT Imaging in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (FAPI-ARVC))
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease associated with fibrofatty myocardial replacement, ventricular arrhythmias, and an increased risk of sudden cardiac death.
- Conditions
- Arrhythmogenic Right Ventricular Cardiomyopathy, FAPI PET, Cardiac Magnetic Resonance Imaging
- Trial name
- FAPI-ARVC (NCT07563660)
- Testing
- 68Ga-DOTA-SA-FAPI PET/CT
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul University - Cerrahpasa
Muscle Injury, Muscle Atrophy
Ultrasound Measurements Hamstring Muscles Thickness
No previous studies have compared the association between muscle thickness (MT) and muscle cross-sectional area (CSA) in healthy volunteers.
- Trial name
- NCT02958254
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Valencia
Prostate Cancer Screening
Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.
The purpose of this study is to compare whether the FDA and Health Canada approved microUS is as effective as the currently used option (MRI) for imaging the prostate gland.
- Trial name
- MUSIC-Screen (NCT06626022)
- Testing
- MRI, ExactVu
- Where
- 9 sites in United States, Canada and 3 more
- Volunteers
- 1,284 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cannabis
Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users
The growing legalization of cannabis across the U.S. is associated with increases in cannabis use, and accordingly, an increase in the number of individuals with cannabis use problems, including cannabis use disorder (CUD).
- Trial name
- iCURE (NCT05401929)
- Testing
- iTBS
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Duke University
Myeloma
Machine Learning in Myeloma Response
Diffusion-weighted Whole Body Magnetic Resonance Imaging (WB-MRI) is a new technique that builds on existing Magnetic Resonance Imaging (MRI) technology.
- Trial name
- MALIMAR (NCT03574454)
- Testing
- Machine Learning (ML)
- Where
- 3 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Psychosis, Schizophrenia
State Representation in Early Psychosis - Project 4
The purpose of this study is to examine state representation in individuals aged 15-45 who have been diagnosed with a psychotic illness, as well as young adults who do not have a psychiatric diagnosis.
- Conditions
- Psychosis, Schizophrenia, Schizophrenia Spectrum and Other Psychotic Disorders, Schizoaffective Disorder
- Trial name
- STEP (P4) (NCT05664594)
- Testing
- Computerized Cognitive Training
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke, Hemiplegia
Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) Over the Brain on the Neurotransmitter Binding
The purpose of this study is to determine whether repetitive transcranial magnetic stimulation (rTMS) over the brain can modulate the binding of neurotransmitter (GABA in this study) to its receptor using the special PET study.
- Trial name
- NCT01819675
- Testing
- Low frequency rTMS, High frequency rTMS
- Where
- South Korea
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Ischemic Stroke, Transient Ischemic Attack
Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular Stroke
This prospective observational study aims to compare the diagnostic performance of non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography in the evaluation of carotid artery disease among…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Carotid Artery Stenosis (Symptomatic and Asymptomatic)
- Trial name
- NCT07756775
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Lipid Metabolism
Physiologic Plasticity of Intramyocardial Lipid Storage
The main goal of the present study was to provide a technical basis for future studies assessing the role of cardiac lipids. More specifically, non-invasive MR-Spectroscopy (MRS) techniques will be used in this study to: 1.
- Trial name
- NCT01921075
- Testing
- normal dietary behavior, Magnetic resonance spectroscopy
- Where
- Switzerland
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Pain
IPRP Repeated Transcranial Magnetic Stimulation (rTMS)
Severe chronic pain is defined as pain persisting for three months or more that significantly impacts daily functioning. It is highly prevalent, occurring in 100,000 to 160,000 youth.
- Trial name
- NCT04561401
- Testing
- Repeated Transcranial Magnetic Stimulation (rTMS), Intensive Pain Rehabilitation Program (IPRP)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Calgary
Diabetes
Effects of Electromagnetic Therapy Versus Laser Therapy on Peripheral Diabetic Neuropathy
This study are to: Evaluate effect of magnetic therapy on peripheral neuropathy in diabetic patients. Evaluate effect of laser therapy on peripheral neuropathy in diabetic patients.
- Trial name
- NCT03049605
- Testing
- Magnetic therapy, laser therapy, Only medical treatment
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Coronary Artery Disease (CAD)
Prognostic Value of High Dose Dobutamine Stress Magnetic Resonance Imaging
High-dose dobutamine/atropine stress cardiac magnetic resonance imaging (DS-MRI) has been incorporated in daily clinical practice for the detection of ischemic heart disease.
- Trial name
- DS-Prognosis (NCT00837005)
- Where
- Germany
- Volunteers
- 2,500 people
- Sponsor
- Heidelberg University
Stroke, Aortic Valve Stenosis
INTERvention With Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation (INTERCEPTavi)
The study aims to evaluate the processes of a pilot single-centre randomised controlled trial (RCT) of carbon-dioxide flushing of transcatheter aortic valves (TAVI-CO2) versus standard saline flushing of valves (TAVI-S) and…
- Conditions
- Stroke, Aortic Valve Stenosis, Silent Cerebral Infarct, Vascular Brain Injury
- Trial name
- INTERCEPTavi (NCT05146037)
- Testing
- CO2 and saline flushing, Saline flushing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Alcohol Use Disorder, Depression
aTBS for Treatment of Depression in AUD
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for improvement of depressive symptoms and drinking behavior in individuals with alcohol dependence.
- Trial name
- NCT03981185
- Testing
- Accelerated theta burst treatment
- Sponsor
- Stanford University
Normal and Abnormal Cardiovascular Physiology
Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) Imaging
Background: Magnetic resonance imaging (MRI) is an important non-invasive tool to study and diagnose cardiovascular disease. MRI scanners use strong magnetic fields and radio waves to create pictures of body organs.
- Trial name
- NCT03581318
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy Volunteers
Development of Hardware and Software for Pulmonary Magnetic Resonance Imaging Using Inhaled Tracer Gases
This is a single centre study. The overarching hypothesis of this study is that MRI with inhaled tracer gases can provide high quality images of lung function to complement conventional 1H MRI.
- Trial name
- NCT04726618
- Testing
- Hyperpolarized 129-xenon gas and Perfluoropropane gas
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Prostate Cancer
MR-guided Focused Ultrasound Treatment of Prostate Cancer: Focal Therapy for Locally Non-Advanced Disease
Since prostate specific antigen (PSA) was introduced as a clinical screening tool for prostate cancer, more men are diagnosed with small foci of cancers instead of the advanced disease.
- Trial name
- NCT01522118
- Testing
- ExAblate 2100; InSightec
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- University of Roma La Sapienza
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