Clinical trials: Magnetism
Heroin Dependence, Opioid Dependence
Biomarkers of Injectable Extended Release Naltrexone Treatment
This study evaluates the biological markers of treatment of opioid dependent individuals with an extended release formulation of the opioid antagonist naltrexone.
- Trial name
- NCT02324725
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pennsylvania
Rectal Adenocarcinoma
Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems
feasibility of using a diffusion sequence of a MRgRT system as an early marker of treatment response during nRCT of rectal adenocarcinoma.
- Trial name
- DWI_RECT_MRGRT (NCT03961776)
- Testing
- MRI-guided radiotherapy by on-board DWI sequences
- Where
- 2 sites in United States, France
- Volunteers
- 39 people
- Sponsor
- Institut Paoli-Calmettes
Vaginal Cancer
Vagina-View Safety and Imaging Feasibility
This prospective, single-arm feasibility study evaluates the use of the Vagina-View (VV) device to guide the placement of a multichannel applicator (MCA) during vaginal brachytherapy.
- Trial name
- Vagina-View (NCT07818850)
- Testing
- Vagina-View (VV) device
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University Health Network, Toronto
Healthy Volunteers, General Anaesthesia
Neuroplasticity Induced by General Anaesthesia
The aim of this study is to use magnetic resonance imaging to explore and compare possible de novo neuroplastic changes induced by the isolated effects of the hypnotic agents sevoflurane and propofol, respectively.
- Conditions
- Healthy Volunteers, General Anaesthesia, Neuroplasticity
- Trial name
- DANA1 (NCT04125121)
- Testing
- Sevoflurane-propofol
- Where
- 2 sites in Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Signe Sloth Madsen
Osteosarcoma
Development of Indices Predicting Response to Pre-operative Chemotherapy in Osteosarcoma Patients
The purpose of this study is to develop indices predicting response to pre-operative chemotherapy in osteosarcoma patients. Histologic response to pre-operative chemotherapy is very important for the ultimate outcome of…
- Trial name
- NCT00686738
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- National Cancer Center, Korea
Parkinson's Disease
Neuroimaging Studies of Depression in Parkinson's Disease
The purpose of this study is to investigate similarities and differences in the neural pathways of depressed Parkinson's patients, non-depressed Parkinson's patients, and healthy controls using magnetic resonance imaging (MRI) of…
- Trial name
- NCT00518258
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lee Blonder
Stroke
Effectiveness of Augmented Reality and Repetitive Transcranial Magnetic Stimulation
This study is to investigate the combined effects of repetitive Transcranial Magnetic Stimulation (rTMS) and Augmented Reality (AR) intervention on cortical excitability, balance, gait, activity in individuals with stroke.
- Trial name
- NCT03750526
- Testing
- rTMS and AR, AR, Conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Medical University Hospital
Alzheimer Disease, Early Onset
Effects of Transcranial Magnetic Stimulation (TMS) and Cognitive Training for Alzheimer Patients
Current diagnosis of Alzheimer disease is made by clinical, neuropsychological, and neuroimaging assessments. Routine structural neuroimaging evaluation is based on nonspecific features, such as atrophy, which is a late feature…
- Trial name
- NCT00909285
- Testing
- TMS stimulation, Cognitive training
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf-Harofeh Medical Center
Glioblastoma, Esophageal Cancer
Serial MRI Scans During Radiation Therapy
This is a phase 1 study to determine the feasibility and utility of using serial magnetic resonance imaging (MRI) to assess treatment response during and after radiation therapy (standard of care cancer treatment) for…
- Conditions
- Glioblastoma, Esophageal Cancer, Radiotherapy, Magnetic Resonance Imaging
- Trial name
- RELAY (NCT04188535)
- Testing
- MRI IMAGING
- Where
- 2 sites in United States
- Volunteers
- 149 people
- Sponsor
- Dana-Farber Cancer Institute
Urinary Incontinence Episodes After the Magnetic Stimulation in Men With Radical Prostatectomy
Pelvic Floor Magnetic Stimulation in Men With Radical Prostatectomy
MS is a technology developed to non-invasively stimulate the central and peripheral nervous system, is applied in the treatment of UI.
- Trial name
- NCT04644614
- Testing
- Magnetic Stimulation - Armchair type
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Pamukkale University
Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
Motor Asymmetry in Progressive Multiple Sclerosis Patients
Project Rational A better understanding of the causes of physical disability is an important unmet need in progressive Multiple Sclerosis patients.
- Trial name
- MAP-MS (NCT04918225)
- Testing
- Magnetic Resonance Imaging, Neurological examination, Multiple Sclerosis Functional Composite
- Where
- France
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Multiple Sclerosis
Study of the Safety and Efficacy of MLN1202 in Patients in Multiple Sclerosis
This was a phase 2a study of MLN1202 to determine safety, tolerability and initial efficacy in patients with relapsing-remitting multiple sclerosis (RRMS). It was conducted in 2 dose cohorts enrolling a total of 50 patients.
- Trial name
- NCT01199640
- Testing
- MLN1202
- Volunteers
- 50 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Multiple Sclerosis, Depression - Major Depressive Disorder
Transcranial Magnetic Stimulation for Depression in Multiple Sclerosis
Canada has one of the highest rates of multiple sclerosis (MS). MS patients experience disabling motor, visual, and sensory symptoms, and a high risk of comorbid major depressive disorder (MDD) and severe fatigue.
- Conditions
- Multiple Sclerosis, Depression - Major Depressive Disorder, Fatigue
- Trial name
- NCT07562074
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Major Depressive Disorder (MDD), Treatment Resistant Depression (TRD)
Ketogenic Diet and Neuromodulation in Treatment Resistant Depression
The goal of this clinical trial is to learn if combining a ketogenic diet with a personalized, accelerated brain stimulation treatment (iTBS) works better than iTBS with a standard healthy diet to reduce depression symptoms in…
- Trial name
- ALIGN (NCT07376018)
- Testing
- Accelerated Intermittent Theta Burst Stimulation (iTBS), Ketogenic Diet, Canadian Food Guide-Aligned Diet
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke
Effect of Transcranial Magnetic Stimulation on Recovery of Upper Limb Among Stroke Survivors
Approximately two thirds of stroke survivors have profoundly impaired function of the upper limb. Currently the main stay of the treatment for upper limb motor function is rehabilitation therapy focusing on repetitive and…
- Trial name
- NCT01938690
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
Breast Cancer, Magnetic Resonance Imaging
Artificial Intelligence Analysis for Magnetic Resonance Imaging in Screening Breast Cancer in High-risk Women
Use Convolutional Neural Networks Analysis for Classification of Contrast-enhancing Lesions at Multiparametric Breast MRI. Build an abbreviated protocal, and investigate whether an abbreviated protocol was suitable for breast…
- Trial name
- NCT04996615
- Testing
- no intervention
- Where
- 2 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Peking University People's Hospital
Rectal Cancer
Prediction of the Response to Neoadjuvant Radiation Chemotherapy Through Texture Analysis Derived From Medical Imaging
In patient with complete pathological response, surgery could be omitted without compromising progression-free or overall survival. A powerful prediction model is needed to guide management of this population.
- Trial name
- RECTOMICS (NCT04920435)
- Where
- 3 sites in France
- Volunteers
- 124 people
- Sponsor
- University Hospital, Brest
Ventricular Tachycardia
Stereotaxis Idiopathic Ventricular Tachycardia (VT) Study
This study will assess the outcomes of using magnetic navigation to treat ventricular tachycardia (VT) or premature ventricular contractions (PVCs) that occur for unknown reasons and are not related to structural heart disease.
- Trial name
- NCT01401608
- Testing
- RF Ablation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Stereotaxis
Alzheimer's Disease - MCI
Noninvasive Brain Stimulation for pAD
Episodic memory refers to the conscious recalling of a personal experience and includes information of an event and the context in which the event took place.
- Trial name
- pADmemory (NCT05468268)
- Testing
- 20 Hz rTMS
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Trento
Congenital Urine Flow Impairment
Change of Urinary Metabolic Profile Secondary to a Congenital Urine Flow Impairment (UFI) by Nuclear Magnetic Resonance (NMR) and Metabolomics Analysis
For the new-born, diagnosis and prognosis of congenital urine flow impairment (UFI) are difficult to confirm only with morphological examination (ultrasonography, intravenous pyelography) and functional examination (dynamic renal…
- Trial name
- ACEU (NCT02792348)
- Testing
- Laboratory biomarker analysis on urine sample
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
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