Clinical trials: Maintenance
Smoking Cessation, Harm Reduction
Adaptive Use of Nicotine Substitution to Maintain Smoking Reduction/Abstinence in Nicotine Responders
To determine whether smokers who initially respond (within 2 weeks) to nicotine products (including nicotine replacement therapy, e-cigarettes, nicotine pouches) by reducing their smoking by ≥50% can be successfully maintained on…
- Trial name
- NCT06554873
- Testing
- Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Insomnia Disorder, Insomnia
Cultural Adaptation of CBTi for the Arab World
The goal of this clinical trial is to learn whether culturally adapted versions of Cognitive Behavioral Therapy for insomnia (CBTi) can reduce insomnia severity and improve sleep and mood outcomes in Arab adults with insomnia.
- Conditions
- Insomnia Disorder, Insomnia, Cultural Adaptation
- Trial name
- NCT07337369
- Testing
- Surface+deep level adaptations, Surface level adaptation
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Laval University
Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis
Hypoxemia in Maintenance Hemodialysis Patients
Previous research has shown that many patients with kidney failure undergoing chronic hemodialysis (HD) have a very low venous oxygen concentration, which may further decrease during dialysis treatments.
- Conditions
- Oxygen Saturation and the Relationship to Other Cardiac Variables, Maintenance Hemodialysis, Kidney Failure, Chronic
- Trial name
- NCT03045796
- Testing
- Oxygen Saturation measured by WristOx
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Crohn Disease
Biologics and Partial Enteral Nutrition Study
Crohn's disease (CD) is a chronic, incurable condition associated with inflammation in the gut lining. It causes diarrhoea, severe abdominal pain, poor nutrition and adversely affects the quality of life of sufferers.
- Trial name
- BIOPIC (NCT04859088)
- Testing
- Partial Enteral Nutrition
- Where
- 4 sites in United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Sleep Quality, Pain
The Effect of Chair-Supported Yoga on Sleep Quality and Pain Level in Elderly Individuals Living in Nursing Homes
This study was designed to evaluate the effect of chair-supported yoga on sleep quality and pain levels in individuals aged 65 and over living in nursing homes.
- Trial name
- NCT07768033
- Testing
- Chair-Supported Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Rüveyda Berk
Insomnia
Nurse-led BBTI for Improving Insomnia Severity
Brief behavioral treatment for insomnia (BBTI) is a new treatment direction for primary and comorbid insomnia; however, its treatment model has not been established in Taiwan.
- Trial name
- NCT05310136
- Testing
- BBTi
- Where
- Taiwan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Healthy Subjects
Gamma-delta Tocotrienol as Potential Maintenance Treatment in Women With Metastatic Breast Cancer
Twelve healthy volunteers who fit the inclusion and exclusion criteria and provide written informed consent to participate in the trial will be recruited to compare the rate and extent of absorption and pharmacokinetics of the…
- Trial name
- GEMM1a (NCT01571921)
- Testing
- Gamma-Delta Tocotrienol and Tocotrienol Rich Fraction
- Where
- Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Normal Weight
Impact of the Timing of Pasta Consumption on Health
To date, the optimal timing for pasta consumption remains uncertain. Based on recent evidence in the field of chrono-nutrition, it is speculated that eating pasta at dinner may have a negative impact on cardio-metabolic health.
- Trial name
- NCT06185634
- Testing
- Dietary intervention - Pasta at dinner, Dietary intervention - Pasta at lunch
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Obstructive Sleep Apnea, Insomnia
Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISA
The comorbidity between obstructive sleep apnea (OSA) and insomnia (COMISA) is common, and associated with poorer sleep quality. CPAP adherence among COMISA patients is worst than among those with OSA only.
- Trial name
- NCT06017921
- Testing
- Eszopiclone 3 mg
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Child Development, Sensory Processing
Development, Sensory Profile, and Sleep Quality in Preschool Children Across Different Caregiving Models
This observational study aims to examine developmental status, sensory processing, and sleep quality in preschool children aged 3 to 6 years across different caregiving models.
- Conditions
- Child Development, Sensory Processing, Sleep Quality, Caregiving Models
- Trial name
- NCT07511465
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Stigma, Social, Drug Abuse Illicit
Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT)
The purpose of this study is to reduce HIV transmission risk among people who inject drugs (PWID) through a multilevel intervention known as LIFT.
- Conditions
- Stigma, Social, Drug Abuse Illicit, HIV (Human Immunodeficiency Virus)
- Trial name
- LIFT (NCT07541131)
- Testing
- LIFT for People Who Use Drugs, LIFT for MMT Providers
- Where
- Kyrgyzstan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Overactive Bladder
Percutaneous Tibial Nerve Stimulation Maintenance: Monthly Therapy or Per Patient Requested Need
The overall objective of this study is to compare the efficacy of the standard monthly maintenance therapy for percutaneous tibial nerve stimulation (PTNS), to sessions as the patient needs (prn) between 2 weeks and 12 weeks…
- Trial name
- NCT03136601
- Testing
- PTNS maintenance
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Weight Loss, Weight Gain
Eating Mindfully to Prevent Weight Regain
The overall objective of this study is to evaluate the efficacy of a mindfulness-based intervention to prevent weight regain in weight-reduced adults.
- Conditions
- Weight Loss, Weight Gain, Eating Behavior, Obesity
- Trial name
- EMPWR (NCT04847843)
- Testing
- Mindfulness Orientated Recovery Enhancement, Control Intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Utah
Primary Insomnia
Safety and Efficacy of Chronic Hypnotic Use
The purpose of the study is to determine how safe and effective it is for people with insomnia to use zolpidem on a nightly basis for one year.
- Trial name
- NCT01006525
- Testing
- zolpidem
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Primary Insomnia
Enhancing Sleep Onset: the Power of Tactile Breath Pacer in Cognitive Behavioral Therapy for Insomnia
The purpose of the study is to evaluate the effectiveness of technology-assisted breathing exercises combined with Cognitive Behavioral Therapy for Insomnia (CBT-I) in primary insomnia patients to investigate.
- Trial name
- MOONBIRD (NCT06475378)
- Testing
- Moonbird, Cognitive Behavioral Therapy for Insomnia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Sleep Quality, Mood Disorders
Effect of the Nintendo Ring Fit Adventure Exergame on Running Completion Time
The coronavirus disease 2019 (COVID-19) outbreak has not only changed the lifestyles of people globally but has also resulted in other challenges, such as the requirement of self-isolation and distance learning.
- Trial name
- NCT05227040
- Testing
- Nintendo Ring Fit Adventure Exergame
- Where
- Taiwan
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Chronic Insomnia, CBT
Mindfulness and Compassive Acceptance for Chronic Insomnia in Comparison With CBT
The main aim of this study is to test the efficacy of a Compassive Acceptance Intervention protocol (developed by the research team) for Chronic Insomnia in comparison with the standard treatment (CBT-I).
- Trial name
- ACTCOM-I (NCT05555108)
- Testing
- ACTCOM-I Intervention, Standard CBT-I Intervention
- Where
- Portugal
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Sleep, Alzheimer Disease
Sleep Trial to Prevent Alzheimer's Disease
The purpose of this study is to determine if treatment with the sleep aid suvorexant can decrease the rate of amyloid-β (Aβ) accumulation in the brain.
- Trial name
- SToP-AD (NCT04629547)
- Testing
- Suvorexant 20 mg
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Insomnia
The Sleepless Brain: Neuroimaging Support for a Differential Diagnosis of Insomnia
One-tenth of the population suffers from insomnia, increasing their risk on other health problems such as depression. Self-reported sleep quality only was historically leading for insomnia diagnosis, but more recently a state of…
- Trial name
- SOMNET (NCT02821234)
- Testing
- MRI
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Quality of Life, Antidepressive Agents
Study of the Effects of Plx on Bioparametric Measurements.
The main objective is to study the effects of the intake of a nutraceutical on health indicators, focused on sleep and stress, as well as cardiovascular (blood pressure...), circulating (cortisol) and body composition parameters…
- Conditions
- Quality of Life, Antidepressive Agents, Depression, Anxiety, Sleep Initiation and Maintenance Disorders
- Trial name
- NCT05128812
- Testing
- PLX
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alicante
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