Clinical trials: Major Surgery Under General Anesthesia
Chronic Kidney Diseases, General Anesthesia
Effect of N-acetylcysteine on Renal Functioning of Chronic Kidney Diseases(CKD) Patients After General Anesthesia
Acute kidney injury (AKI) is one of the most serious and frequent complication of general anesthesia. Patients suffer from chronic kidney diseases (CKD) predispose to develop AKI.
- Trial name
- NCT01251029
- Testing
- N-acetylcysteine, Siran (N-acetylcysteine)
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
Anesthesia, General, Major Abdominal Surgeries
The Impact of Multimodal Brain Monitoring on Postoperative Outcomes in Elderly Patients Undergoing Major Abdominal Surgery
The purpose of this clinical trial is to investigate the effect of multimodal brain monitoring under general anesthesia on postoperative outcomes in elderly patients undergoing abdominal surgery.The research hypothesis is that…
- Trial name
- NCT07713355
- Testing
- Multimodal brain monitoring guided anesthesia, Bispectral Index(BIS) monitoring guided anesthesia
- Where
- 4 sites in China
- Volunteers
- 368 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Kidney Injury, Major Surgery Under General Anesthesia
Risk Factors of Postoperative Acute Kidney Injury and Mortality Among Hospitalized Patients Undergoing Major Surgery
The goal of this retrospective observational study is to learn about the intervenable risk factors of postoperative acute kidney injury (AKI) and in-hospital mortality among adult patients undergoing major surgery.
- Conditions
- Acute Kidney Injury, Major Surgery Under General Anesthesia, Mortality, Postoperative Complication
- Trial name
- NCT07136194
- Where
- China
- Volunteers
- 21,533 people
- Sponsor
- Peking University First Hospital
Total Fluid Volume Decreased
Preoperative Ultrasound Guided Evaluation of SVC-CI and IVC -CI as Predictors of Hypotension After Induction of Anaesthesia in Major Onco-surgery
Patients undergoing major Oncosurgeries are fluid deficit due to preoperative fasting , inadequate intake due to disease hence prone to development of hypotension after induction of general anaesthesia owing to vasodilatory…
- Trial name
- SVC IVC CI (NCT05548920)
- Testing
- Ultrasound guided Superior Vena Cava Collapsibility Index, Inferior Vena Cava Collapsibility Index
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Delirium, Cognitive Impairment
Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
The purpose of this study is to determine what percentage of patients have cognitive problems (for example, memory or concentration difficulties) after surgery and anesthesia, what the characteristics of these problems are, and…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Decline, Cognitive Change
- Trial name
- NCT03337282
- Testing
- Protocolized general anesthesia
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Major Surgery Under General Anesthesia
The Effects of Ambient Temperature and Forced-air Warming on Intraoperative Core Temperature
The purpose of this study is to determine: 1. the effect of ambient temperature on the rate of core temperature change from 1 to 3 hours after induction of anesthesia (linear phase of the hypothermia curve) in major operations…
- Trial name
- NCT02715076
- Testing
- Ambient Temperature 19°C, Ambient Temperature 21°C, Ambient Temperature 23°C
- Where
- China
- Volunteers
- 292 people
- Sponsor
- Peking Union Medical College Hospital
Major Abdominal Surgery, General Anesthesia
Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation
In this study, the investigators propose to explore the hemodynamic variations induced by vasopressin and its influence on cardiac output, mean systemic pressure, and venous return resistance measured through cardiopulmonary…
- Conditions
- Major Abdominal Surgery, General Anesthesia, Mechanical Ventilation, Vasopressin Infusion
- Trial name
- CORVaso (NCT04935814)
- Testing
- Vasopressin, Arginine
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Preoperative Warming, Prewarming
Preoperative Patient Warming for Prevention of Perioperative Hypothermia in Major Abdominal Surgery
The study should evaluate how long patients undergoing major abdominal surgery under combined general/epidural anaesthesia have to be actively warmed preoperatively to prevent perioperative hypothermia and postoperative…
- Conditions
- Preoperative Warming, Prewarming, Perioperative Hypothermia, General Anaesthesia
- Trial name
- THER-6 (NCT01795482)
- Testing
- Forced-air warming
- Where
- 2 sites in Germany
- Volunteers
- 99 people
- Sponsor
- University Hospital Schleswig-Holstein
Major Surgery Under General Anesthesia
Perioperative Accuracy of the Raiing Wireless Axillary Thermometer
A new wireless axillary thermometer from Raiing Medical uses a proprietary system, iThermonitor (WT701), to provide better estimates of core temperature than a conventional axillary probe.
- Trial name
- NCT02756910
- Testing
- iThermonitor (WT701)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking Union Medical College Hospital
Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder
The Role of Neuroinflammation on Neurocognitive Outcome in Cardiac Surgery
RATIONALE: Postoperative cognitive changes are common after cardiac surgery and can be categorised into three main types: postoperative delirium (POD), delayed neurocognitive recovery (DNCR) and postoperative neurocognitive…
- Conditions
- Postoperative Neurocognitive Dysfunction, Postoperative Neurocognitive Disorder, Cardiac Surgery, Major Surgery Under General Anesthesia
- Trial name
- INOCS (NCT07200726)
- Testing
- Observational study design - no intervention
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Ziekenhuis Oost-Limburg