Clinical trials: Male Fertility
Male Infertility, Low Sperm Quality
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Male Fertility
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the…
- Conditions
- Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy
- Trial name
- NCT07740161
- Testing
- WeNatal For Him Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Virtual Reality
Erotica by Virtual Reality on Sperm Donors
Objective To study whether erotica by virtual reality (VR) during masturbation influences the quality of sperm donor ejaculates. Hypothesis Erotica by virtual reality improves ejaculate quality.
- Trial name
- NCT05457764
- Testing
- Virtual reality headset
- Where
- 4 sites in Denmark
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cryos International
Infertility, Overweight and Obesity
Healthy Parents - Healthy Children. Weight Loss Before Fertility Treatment
The detrimental effect of overweight and obesity on fecundity has been well documented. The investigators wish to investigate the intervention program for weight loss before fertility treatment.
- Conditions
- Infertility, Overweight and Obesity, Weight Loss, Vaginal Flora Imbalance
- Trial name
- NCT04721938
- Testing
- Systematic weight loss intervention
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
DSD, 46,XY, DSD, Ovotesticular
Gonadal Tissue Cryopreservation for Fertility Preservation in Children With a Disorder of Sex Development
The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer).
- Conditions
- DSD, 46,XY, DSD, Ovotesticular, DSD, Sex Chromosome, Disorders of Sex Development
- Trial name
- DSD (NCT06692049)
- Testing
- Gonadectomy
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Erin Rowell
Male Infertility
Herbal Tonic Fertile Supplement(ZO2C5)
The purpose of this study is to determine whether the effect of mixed herbals drug (citrus, citrolus vol, lan, carrot seed, zingiber, onion, basil, cinnamon) administration on male infertility: oligospermia
- Trial name
- (ZO2C5) (NCT01895816)
- Testing
- coated tablet
- Where
- Iran
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Arash Khaki
Male Infertility, Hypogonadism, Male
The Impact of Sinopharm COVID-19 Vaccination on Male Fertility
The investigators shall study the effect of Sinopharm vaccination on semen parameters and serum testosterone
- Trial name
- NCT04946565
- Testing
- Semen analysis
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Male Infertility, Obesity
Investigating the Physiological Effects of Weight Loss on Male Fertility
The purpose of this study is to determine the physiological effects of weight loss on seminal parameters in male participants with reduced reproductive capacity.
- Conditions
- Male Infertility, Obesity, Weight Loss
- Trial name
- NCT03553927
- Testing
- Low Energy Diet, NHS advice on healthy eating
- Where
- United Kingdom
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Infertility, Female, Infertility, Male
Knowledge and Attitude Towards Fertility Among Emirati Infertile Patients
Infertility is on the rise worldwide due to multiple reasons. Proper and timely diagnosis makes the treatment easier and more acceptable by the couple.
- Trial name
- NCT06250231
- Testing
- No intervention
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Healthy
Assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects
The is an assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects.
- Trial name
- NCT01365000
- Testing
- NKTR118 Formulation 1, NKTR118 Formulation 2, NKTR118 Formulation 3
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Severe Oligoasthenoteratozoospermia, Sperm Quality
PRP Improves Blastocyst Formation in ICSI Cycles
The goal of this clinical trial is to learn if platelet rich plasma (PRP) works to improve embryo development rates and embryo quality in IVF cycles, involving male adult patients with severe sperm disorders.
- Conditions
- Severe Oligoasthenoteratozoospermia, Sperm Quality, Spermatazoa Disorders, Sperm Parameters in Fertile and Infertile Men
- Trial name
- PRP ICSI SOAT (NCT07579858)
- Testing
- Platelet Rich Plasma
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stella Maris Women and Children Hospital
Fertility, Male, Sub-Fertility, Male
Study of the Consumer Use of a New Home Test to Measure Sperm Concentration
The objective of the study is to evaluate the agreement in measurement of sperm concentration in human semen between lay users with TRAK and a recognized reference method.
- Trial name
- NCT02475395
- Testing
- TRAK device
- Where
- 3 sites in United States
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Sandstone Diagnostics
Infertility, Male
The Effect of a Multimodal Lifestyle Program on Male Fertility
A non-pharmacological study, which examines the effect of lifestyle intervention on sperm quality among men in fertility treatment.
- Trial name
- NCT04761250
- Testing
- Lifestyle
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Sperm DNA Fragmentation, Male Fertility
Impact of Telomere Biology and Sperm DNA Fragmentation on Embryonic Development
The proposed project we intend to assess the implication of the telomeric pathway in male infertility. To get this, several analyzes will be carried out: 1. Determination of the TL by means of two methods: Q-FISH and PCR. 2.
- Conditions
- Sperm DNA Fragmentation, Male Fertility, Telomeres, Sperm
- Trial name
- NCT05508217
- Where
- Spain
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Tolerability
Study to Investigate Single Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects
1. The main purpose of this study is to assess the safety and tolerability of AZD5213 after single oral doses. 2. Another purpose of this study is to evaluate the pharmacokinetics (also called PK - how the study drug enters and…
- Trial name
- NCT01121302
- Testing
- AZD5213
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Male Infertility
Home Semen Analysis Tests As a Screening Tool for Fertility Patients
Infertility, defined as the inability to conceive after 12 months of regular unprotected intercourse, is estimated to affect 1 in 7 heterosexual couples.
- Trial name
- NCT06188936
- Testing
- ExSeed®, Survey
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Azoospermia, Elasticity Imaging Techniques
Testicular Elastography for Microscopic Testicular Sperm Extraction
Before commencing our study, we obtained approval from the local ethics committee. The study focused on patients who visited our urology outpatient clinic for infertility between January 2020 and March 2021.
- Conditions
- Azoospermia, Elasticity Imaging Techniques, Fertility Preservation
- Trial name
- NCT06524258
- Testing
- testicular elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Uşak University
Infertility, Male
Male Reproduction COVID Sequelae Study (MARCOS).
The purpose of this study is to investigate the effects of COVID-19 Vaccination on semen parameters and to determine how long these possible changes may last following vaccination.
- Trial name
- NCT04665258
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Male Fertility
Efficacy Evaluation of a Novel Diagnostic Assay Which is the Basis for Seaforia Diagnostic System
Evaluation of specificity and sensitivity of Seaforia- an vitro diagnostic system for evaluating semen quality.
- Trial name
- NCT00734981
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lotus Bio Inc.
Healthy Volunteer
AZD2423 Single Ascending Dose Study in Healthy Japanese Subjects
This is a Phase I, single centre, randomised, double-blind, placebo-controlled, parallel group study to assess the safety, tolerability and pharmacokinetics of AZD2423 following single ascending dose administration to healthy…
- Trial name
- JSAD (NCT00970775)
- Testing
- AZD2423
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Infertility, Male
Single and Double DNA Strand Breaks in Males With Unexplained Infertility Attending Fertility Treatment
The aim of this study is to investigate the extent of double-stranded DNA damage in sperm in men with unexplained infertility.
- Trial name
- NCT05846256
- Testing
- Sperm DNA Fragmentation
- Where
- Denmark
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan