Clinical trials: Male Sexual Dysfunction
Erectile Dysfunction
Stress Management Using an App to Improve Response With PDE5 Inhibitors in Men With Erectile Dysfunction.
The aim of this study is to determine if patients with ED taking PDE5 inhibitors (e.g. Viagra, CIalis, Levitra, Stendra) and experiencing performance anxiety will benefit using a user-friendly stress reducing phone app, Serenita.
- Trial name
- NCT02757807
- Testing
- Utilization of Serenita for Relaxation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eco Fusion
Erectile Dysfunctions
Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder Patients
The goal of this clinical trial is to evaluate whether daily dosing with tadalafil 5 mg combined with on-demand sildenafil 100 mg can improve erectile function in men with erectile dysfunction (ED) who do not respond to PDE5…
- Trial name
- NCT07391579
- Testing
- Tadalafil 5 mg & Sildenafil 100mg
- Where
- 11 sites in Egypt
- Volunteers
- 500 people
- Sponsor
- Mansoura University
Erectile Dysfunction, Sexual Dysfunction
BAY38-9456 - Supportive Trial for Spinal Injury
BAY 38-9456 10 mg and 20 mg can be given as safe and efficacious medications to patients with spinal cord injury suffering from erectile dysfunction, and that erectile dysfunction can be improved by uptitration to BAY 38-9456 20…
- Conditions
- Erectile Dysfunction, Sexual Dysfunction, Spinal Cord Injury
- Trial name
- NCT00652262
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 3 sites in Japan
- Volunteers
- 32 people
- Sponsor
- Bayer
Vulvovaginal Atrophy, Genital Disorder
Psychometric Validation of the Portuguese DIVAS-Q in Women With Vulvovaginal Atrophic Symptoms
To determine the reliability and validity of the Portuguese version of the DIVA questionnaire in Portuguese women. This validation will support its use both in research and in routine clinical practice in this population.
- Conditions
- Vulvovaginal Atrophy, Genital Disorder, PROMs
- Trial name
- DIVAS-Q (NCT07250490)
- Where
- Portugal
- Volunteers
- 300 people
- Sponsor
- Instituto Politécnico de Leiria
Erectile Dysfunction
Study Evaluating the Efficacy and Safety of Flexible-dose Vardenafil in Subjects With Erectile Dysfunction
Study to investigate the efficacy and safety of Vardenafil
- Trial name
- NCT00658177
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Volunteers
- 463 people
- Sponsor
- Bayer
Pain, Postoperative, Neural Therapy of Huneke
Evaluation of the Neural Therapy Effect on Long Term Postoperative Discomforts in Patients Who Undergo Bilateral Tubal Ligation
The aim of this study was to explore the effect of neural therapy on postoperative pain and discomfort such as abdominal swelling; and gynecologic symptoms such as dysmenorrhea, dyspareunia, amount of menstrual bleeding and…
- Conditions
- Pain, Postoperative, Neural Therapy of Huneke, Dysmenorrhea, Dyspareunia
- Trial name
- NCT03761862
- Testing
- Neural Therapy
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Vulvar Atrophy, Vulvovaginal Signs and Symptoms
Retrospective Cohort Study of Symptoms and Quality of Life in Women With Genitourinary Syndrome of Menopause.
The goal of this clinical trial is to retrospectively identify the most prevalent symptoms of genitourinary syndrome of menopause (GSM) among postmenopausal women and to evaluate their impact on quality of life.
- Conditions
- Vulvar Atrophy, Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause (GSM), Quality of Life
- Trial name
- NCT07737782
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Mucosa Innovations, S.L.
Urinary Incontinence, Fecal Incontinence
Perineal Massage and Pelvic Floor Exercise in the Antenatal Period
This study aimed to determine the effect of perineal massage and pelvic floor exercise in the antenatal period on sexuality and urinary and fecal incontinence in the postpartum period.
- Conditions
- Urinary Incontinence, Fecal Incontinence, Sexual Dysfunction, Sexuality
- Trial name
- NCT05624060
- Testing
- Pelvic Floor Dysfunction Prevention Training, Pelvic Floor Dysfunction Prevention Training and Perineal Massage, Pelvic Floor Dysfunction Prevention Training and Perineal Massage and Pelvic Floor Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bitlis Eren University
Premature Ejaculation, Ejaculation
Effect of Prostatic Urethra and Seminal Vesicle Morphometry on Ejaculation
The goal of this observational study is to learn whether the size and shape of the prostatic urethra and seminal vesicles - measured on multiparametric prostate MRI (mpMRI) - are related to premature ejaculation (PE) severity in…
- Trial name
- NCT07614854
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Erectile Dysfunction, Smoking
A Comparative Pharmacokinetic and Pharmacodynamic Study of Sildenafil in Adult Smokers and Non Smokers
Smokers are at higher risk of developing Erectile dysfunction (ED) independent of age and comorbidities. Sildenafil is a cytochrome p3A4 (CYP3A4) substrate used for enhancing the erectile function in males.
- Conditions
- Erectile Dysfunction, Smoking, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT04100759
- Testing
- Sildenafil 50 mg Oral Tablet
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Erectile Dysfunction
Satisfaction With Phosphodiesterase 5 Inhibitors Treatment In Patients With Cardiovascular Risk
Evaluate satisfaction in people treated with IPDE5 inhibitors over time
- Trial name
- TIERRA (NCT00874185)
- Volunteers
- 720 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Erectile Dysfunction
Drug Interaction Study of Avanafil and Enalapril or Amlodipine
The purpose of this study is to determine the change in the blood pressure and pulse rate, pharmacokinetics and the safety when avanafil is taken with either enalapril or amlodipine.
- Trial name
- NCT01117038
- Testing
- avanafil and enalapril, avanafil and amlodipine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Erectile Dysfunction
A Bioavailability Study of LY2452473 and Tadalafil
This study compares LY2452473 taken orally as a 5 milligram (mg) capsule at the same time as a 5 mg tadalafil tablet with three different combination tablets (LY900010) of 5 mg LY2452473 and 5 mg tadalafil taken orally.
- Trial name
- NCT01401543
- Testing
- LY2452473, Tadalafil, LY900010
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Transgender Men, Blood Pressure
Mechanisms of Blood Pressure Dysfunction in Transmen Receiving Testosterone
The purpose of this research is to explore the effects of chronic androgen exposure on sympathetic nervous system activity (SNSA) and baroreflex control of blood pressure responses in transgender men (trans men) taking gender…
- Conditions
- Transgender Men, Blood Pressure, Hyperandrogenism
- Trial name
- NCT04524325
- Testing
- Trans men
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Erectile Dysfunction
A Study of LY900010 in Erectile Dysfunction
The primary purpose of the study is to compare the efficacy of LY2452473 + tadalafil to tadalafil alone in improving the erectile function (EF) of men with erectile dysfunction (ED) who incompletely respond to tadalafil alone.
- Trial name
- NCT01160289
- Testing
- LY2452473, tadalafil
- Where
- 36 sites in United States
- Volunteers
- 410 people
- Sponsor
- Eli Lilly and Company
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Erectile Dysfunction
Pharmacokinetics of Sildenafil Following Administration of an Chewable Tablet of Sildenafil Relative to Viagra® Conventional Oral Tablet in Healthy Volunteers
This is a single dose open-label comparative pharmacokinetic study to assess the pharmacokinetic characteristics of sildenafil between HIP0908 (chewable tablet) and Viagra (tablet) in healthy male subjects.
- Trial name
- NCT01514903
- Testing
- HIP0908, viagra
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Erectile Dysfunction
TRIP-patch vs Duplex
To measure saturation and desaturation of the cavernosal tissue with a cutaneous placed penile sensor, before and during full rigidity.
- Trial name
- NCT06402097
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- St. Antonius Hospital
Erectile Dysfunction
The Effect of Low Intensity Shockwave Therapy for ED in Post Radical Prostatectomy Patients Who Didn't Respond to PDE5i
Low Intensity Shock Wave Therapy (LI-ESWT) was shown to have a beneficial effect on ED patients responding to PDE5i's. This study aimed to determine the capability of LI-ESWT to affect patients who underwent radical prostatectomy…
- Trial name
- LI-ESWT (NCT01274949)
- Testing
- LI-ESWT
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
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