Clinical trials: Malignant Neoplasm of Abdomen
Malignant Neoplasm of Abdomen, Surgery
TAP Versus Thoracic Epidural in Major Abdominal Resections
The purpose of this study is to compare two standard methods of pain control management used at Spectrum Health for patients undergoing major surgery. The two methods being compared are the thoracic epidural and the TAP block.
- Trial name
- NCT02197988
- Testing
- Exparel 1.33% (20ml Volume), 0.125% bupivicaine with 2 mcg/ml Fentanyl.
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Corewell Health West
Pulmonary Cancer, Breast Neoplasms
18F-FSPG PET/CT Imaging in Patients With Cancers
This study aims to compare the diagnostic performance of 18F-FDG and 18F-FSPG PET/CT in lung, breast, and abdominal cancers before undergoing therapy.
- Conditions
- Pulmonary Cancer, Breast Neoplasms, Abdominal Cancer
- Trial name
- NCT03144622
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Malignant Peritoneal Neoplasm, Malignant Retroperitoneal Neoplasm
Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal Carcinomatosis
This phase Ib trial studies the side effects and best dose of nivolumab with or without ipilimumab in treating patients with female reproductive cancer that has come back (recurrent) or is high grade and has spread extensively…
- Conditions
- Malignant Peritoneal Neoplasm, Malignant Retroperitoneal Neoplasm, Metastatic Cervical Carcinoma, Metastatic Endometrial Carcinoma
- Trial name
- NCT03508570
- Testing
- Ipilimumab, Laboratory Biomarker Analysis, Nivolumab
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Mechanical Ventilation Complication
Effects of Growth Hormone on Difficult Ventilator Weaning Patients
Major abdominal surgeries may be followed by postoperative pulmonary complications (PPCs). These complications are common and can cause significant morbidity and mortality.
- Trial name
- NCT03717168
- Testing
- Recombinant human growth hormone, Control
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- National Cancer Institute, Egypt
Head and Neck Cancer, Thoracic Cancer
Evaluation of On-Couch CBCT Image Quality
This is a prospective, single-arm, single-site study designed to generate data describing the image quality and applicability/useability of a high-performance, on-couch CBCT imaging technology (HyperSight) in patients receiving…
- Conditions
- Head and Neck Cancer, Thoracic Cancer, Abdominal Cancer, Pelvic Cancer
- Trial name
- NCT06576908
- Testing
- HyperSight Imaging
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Varian, a Siemens Healthineers Company
Abdominal Cancer
Effectiveness of Pain Management Interventions in Patients With Abdominal and Pelvic Cancer
The goal of this prospective observational study is to observe the effectiveness of pain management interventions in patients with abdominal and pelvic cancer pain.
- Trial name
- NCT07357350
- Volunteers
- 100 people
- Sponsor
- Aga Khan University
Abdominal Cancer
Efficacy of Transverses Abdominis -Plane Block With Bupivacaine Versus Bupivacaine With Morphine Postoperatively
This study aims to compare the analgesic efficacy of transversus abdominis-plane block with bupivicaine versus bupivacaine with morphine in patients undergoing major abdominal cancer surgery.
- Trial name
- NCT02566096
- Testing
- transversus abdominis-plane block with local anesthetic 20 ml of bupivacaine 0.5% + 10 mg morphine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intrathecal Dexmedetomidine, Pediatric Cancer Surgery
Intrathecal Dexmedetomidine Versus Fentanyl With Bupivacaine in Children Undergoing Major Abdominal Cancer Surgery
In this study the investigators aim to determine the analgesic effect and side effects of intrathecal fentanyl and dexmedetomidine as adjuvant to local anesthetics in pediatric patients undergoing major abdominal cancer surgeries.
- Trial name
- NCT02861716
- Testing
- Bupivacaine, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Egypt Cancer Institute
Ovarian Cancer, Peritoneal Carcinomatosis
Olvi-Vec Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer
The purpose of this study is to determine if Olvi-Vec oncolytic immunotherapy is well tolerated with anti-tumor activity in patients diagnosed with recurrent or refractory ovarian cancer and peritoneal carcinomatosis.
- Conditions
- Ovarian Cancer, Peritoneal Carcinomatosis, Fallopian Tube Cancer
- Trial name
- NCT02759588
- Testing
- Olvi-Vec, Platinum-doublet with or without bevacizumab
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Genelux Corporation
Thyroid Neoplasm, Thyroid Carcinoma
Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer
Medullary thyroid carcinoma (MTC) is a rare tumor arising from C cells of the thyroid gland and belonging to the endocrine tumors.
- Conditions
- Thyroid Neoplasm, Thyroid Carcinoma, Medullary Carcinoma
- Trial name
- DOPMET (NCT00647140)
- Testing
- 18F-L-DOPA PET
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abdominal Cancer
Safety and Efficacy of Intrathecal Morphine in Children
Postoperative pain in pediatrics can usually be well controlled with a combination of analgesics including acetaminophen ( paracetamol) ,NSIADS, opioids , and local/regional anesthesia.The use of epidural and subarachnoid…
- Trial name
- NCT03120403
- Testing
- intrathecal morphine
- Volunteers
- 45 people
- Sponsor
- Alaa Ali Mohamed Elzohry
Ureteral Obstruction
Drainage of Malignant Extrinsic Ureteral Obstruction Using the Memokath Ureteral Stent
The purpose of this study is to evaluate the safety and efficacy of the Memokath 051 ureteral stent as a long-term temporary and minimally invasive means of providing ureteral drainage in the setting of malignant extrinsic…
- Trial name
- NCT00166361
- Testing
- Memokath 051 Ureteral Stent, JJ Stent
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Mayo Clinic
Metastatic Ovarian Carcinoma, Peritoneal Carcinomatosis
Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Associated With Systemic Chemotherapy in Women With Advanced Ovarian Cancer
Women with history of tumor response insufficient to allow complete cytoreductive surgery after three cycles of previous neoadjuvant systemic carboplatin-paclitaxel chemotherapy will be prospectively recruited in this trial.
- Conditions
- Metastatic Ovarian Carcinoma, Peritoneal Carcinomatosis, Stage III Ovarian Cancer, Stage III Fallopian Tube Cancer
- Trial name
- PIPACOVA (NCT04811703)
- Testing
- Combined PIPAC / IV chemotherapy treatment
- Where
- 6 sites in France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Abdominal Cancer, Thoracic Cancer
Validate the Safety and Feasibility of the CT-guided Interventional Robot in Percutaneous Biopsy Procedure.
This multicenter, randomized controlled trial aims to investigate whether the interventional robot can be well and safely used for percutaneous needle biopsy compared with the freehand needle biopsy method under CT guidance in…
- Trial name
- NCT06484764
- Testing
- CT-fluoroscopy guided robot-assisted biopsy of thoracic and abdominal lesions, Freehand CT-guided percutaneous needle biopsy of thoracic and abdominal lesions
- Where
- 3 sites in China
- Volunteers
- 166 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Malignant Mesothelioma
Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving the drugs directly into the tumor after surgery and combining them with radiation therapy may kill…
- Trial name
- NCT00024271
- Testing
- recombinant interferon gamma, cisplatin, doxorubicin hydrochloride
- Where
- United States
- Sponsor
- Herbert Irving Comprehensive Cancer Center
Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface, Malignant Peritoneal Mesothelioma
αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies
This trial is to determine the safest dose of a triple combination (chemokine modulatory regimen or CKM) of celecoxib, interferon alfa (IFN), and rintatolimod that can be given with a DC vaccine as treatment of peritoneal surface…
- Conditions
- Malignant Neoplasm of Pancreas Metastatic to Peritoneal Surface, Malignant Peritoneal Mesothelioma, Peritoneal Carcinomatosis
- Trial name
- NCT02151448
- Testing
- DC vaccine, Celecoxib, Interferon Alfa-2b
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- David Bartlett
Prehabilitation
Application of Ergogenic Aids to the Prehabilitation of Abdominal Cancer Patients Undergoing Cancer Surgery
The purpose of the proposed study is to measure surgical recovery, including the length of hospital stay, incidence of perioperative complications, and mortality at 90 days post-surgery, in surgical patients with abdominal…
- Trial name
- NCT04073381
- Testing
- Prehabilitation Program
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Texas at Austin
Cancer
Radiofrequency Splanchnic Denervation ,Neurolytic Retrocrural Celiac Plexus Block Chronic Upper Abdominal Cancer Pain
To compare between the efficacy of radiofrequency splanchnic denervation and neurolytic retrocrural celiac plexus block in chronic upper abdominal cancer pain
- Trial name
- NCT06678061
- Testing
- radiofrequency
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Abdominal Cancer
A Seven-day Preoperative Exercise Training Program in People With Abdominal Cancer
Background: Preoperative exercise training programs of long duration, that delay surgical resection of tumors, may not be feasible in the treatment of malignant disease.
- Trial name
- NCT04114422
- Testing
- Seven-day preoperative exercise training program
- Where
- Brazil
- Sponsor
- Universidade Cidade de Sao Paulo
Dexmedetomidine
Dexmedetomidine in Splanchnic Nerve Neurolysis
Malignancy related abdominal and pelvic pain can be debilitating and affects survival as well as quality of life. Pain from cancer and its treatments can result in anxiety, depression, fear, anger, helplessness, and hopelessness…
- Trial name
- NCT05291364
- Testing
- Group 1, Group 2
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University